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Test 1
dental, preanesthetic, anesthetic agents
39
Veterinary Medicine
Undergraduate 1
02/01/2011

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Term
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Definition
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Term
tranquilize
Definition
alteration of behavior. quiets and calms the patient.
awake, no analgesia, calm. implies calm, not sleepy like sedation.
Term
sedation
Definition
patient is awake, but is slightly depressed and sleepy.
decreased activity and excitement. implies sleepier than tranquilized.
Term
anesthesia
Definition
an/esthesia. without feeling or sensation. patient is
asleep, cannot be awakened (until drug wears off), has amnesia and loss
of reflexes
Term
analgesia
Definition
relief of pain without loss of consciousness
Term
amnesia
Definition
loss of memory - patient does not remember procedure
Term
ataxia
Definition
incoordination - stumbling gait, falling to side, etc
Term
hypnosis
Definition
greater depression than sedation. patient is asleep but can
be awakened.
Term
narcosis
Definition
patient is asleep, can be awakened but goes back to sleep.
implies good analgesia
Term
preanesthesia
Definition
period immediately preceding the induction of
anesthesia
Term
pre-anesthetic medication
Definition
“pre-op” - any drug given within 1 hour
before anesthesia
Term
anesthetist
Definition
a person, such as a nurse or technician, trained in the
administration of anesthetics – LVT
Term
anesthesiologist
Definition
a physician or veterinarian specializing in
anesthesiology – DVM
Term
informed consent
Definition
a. explain procedure, anesthesia, and risks to owner.
b. release form - and get owner to sign a release form.
Term
Features of General Anesthesia
Definition
-unconsciousness
-analgesia
-amnesia
-muscle relaxation
-loss of reflexes
Term
Regional Anesthesia
Definition
-patient is awake
-requires restraint
-blocks feeling from large area of body
ex: epidural
-used more in humans, LA
Term
Local Anesthesia
Definition
-local analgesia
-patient is awake
-requires restraint
-blocks feeling from small area of body
-usually injectable
-local infiltration
-may be in spray form or otherwise
applied topically
Term
Local Anesthesia
Definition
-less stressful than general anesthesia
-names of most drugs used for this
purpose end in “-ocaine”
-lidocaine
Term
Other Uses for Diazepam
Definition
-treat seizure in progress
-appetite stimulant in cats
-small dose IV
-behavior modification in dogs, cats, and people
Term
Preanesthetic Agents
Definition
-drugs given before the general anesthetic drugs
so the animal is already under their effects when anesthesia begins
Term
Reasons for Use of Preanesthetic Drugs
Definition
-tranquilize patient…
-reduce side effects…
salivation
bradycardia
arrhythmias
vomiting

-balanced anesthesia…
-analgesia
Term
Balanced Anesthesia
Definition
using several drugs in order to reduce dose of each
benefits - less side effects, earlier recovery
Term
Analgesia
Definition
some, not all, pre-op drugs are analgesic
help with catheterization
may provide post-op relief for short procedures
Term
Classes of Preanesthetic Drugs
Definition
-anticholinergics…
-tranquilizers and sedatives
-phenothiazines…
-benzodiazepines…
-thiazine derivatives
Term
Anticholinergics
Definition
-parasympatholytics
-main examples
-atropine
-glycopyrrolate
Term
Anticholinergics
Definition
-mode of action…
-sympathetic effects…
-review of autonomic NS…
-parasympathetic receptors…
-action…
method of use…

atropine…
glycopyrrolate
Term
Anticholinergics Sympathetic Effects
Definition
anticholinergics have sympathetic effects
anti - against
cholinergic - acetylcholine
parasympathetic neurotransmitter
Term
Sympathetic NS
Definition
“fight or flight”
increase HR, RR, BP
decrease GI function
epinephrine, norepinephrine
Term
Parasympathetic NS
Definition
“rest and restore”
decrease HR, RR, BP
increase GI function
acetylcholine - Ach
Term
Parasympathetic Receptors
Definition
nicotinic receptors…
muscarinic receptors
Term
Nicotinic Receptors
Definition
in neural ganglia
groups of nerve cell bodies
between spinal cord and peripheral nerves
located in both sympathetic and parasympathetic neurons
also found at neuromuscular junction of skeletal muscle cells

stimulation shows a wide variety of clinical signs
Term
Muscarinic Receptors
Definition
at final terminals - at ends of nerves
on heart, GIT, bronchi, iris, salivary and tear glands, etc
typically located in neurons associated with parasympathetic nervous system
stimulation produces parasympathetic signs
slow HR, miosis, increased GI activity, etc
Term
Action - anticholinergic drugs
Definition
block acetylcholine at muscarinic receptors of parasympathetic NS
do not affect nicotinic receptors
Term
Method of Use of Anticholinergics (administration)
Definition
SQ - onset 20 minutes
IM - more rapid onset
IV - almost immediate onset - use with care
may mix with ace, ketamine, butorphanol
do not mix with diazepam
duration 60-90 minutes
Term
Atropine
(method, dose)
Definition
from European deadly nightshade plant Belladonna atropa
SA 0.5 mg / ml
LA 2.2 mg / ml
Term
Effects of Atropine
Definition
blocks stimulation of vagus nerve…
reduces salivation…
reduces GI activity
mydriasis…
reduces tear secretions…
bronchodilation…
no analgesia
Term
Atropine blocks stimulation of the ________________ nerv
Definition
vagus
Term
Procedures that Stimulate the Vagus Nerve
Definition
intubation
handling viscera
certain anesthetics
inhalation agents, xylazine, some opioids
Term
Effects of Vagus Nerve Stimulation
Definition
bradycardia
reduced cardiac output (CO)
other increases in parasympathetic activity
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