Term
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Definition
| Enzymes that catalyze the same rxn but have a different amino acid sequence |
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Term
| The 3 markers for a myocardial infarction and their half lives |
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Definition
| CK (early, 18hrs), AST (late, 1 day for cytosolic) and LDH (late, 5 days) |
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Term
| The 3 isozymes of Creatine Kinase |
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Definition
| CK-BB (CK-1), CK-BM (CK-2), CK-MM (CK-3) |
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Term
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Definition
| Known as CK-1, is present in the brain and intestinal smooth muscle, and does not accumulate in the serum |
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Term
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Definition
| Known as CK-2, comprises ~30% of CK myocardium, accounts for the 5% elevation in blood after an MI |
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Term
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Definition
| Known as CK-3, found mainly in skeletal muscle (~98% isozyme), Muscular dystrophy and Rhabdomyolosis lead to ~5% elevated serum levels of isozyme |
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Term
| 24hrs after an MI, which CK isozymes are elevated in serum |
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Definition
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Term
| Determining the severity of an MI |
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Definition
| The percentage of CK-MB of total CK |
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Term
| This value is indicative of an MI |
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Definition
| A 5% serum increase in CK-MB indicates this |
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Term
| Three proteins that increase in serum hours after an MI |
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Definition
| cTroponin-I, cTroponin-T, Myoglobin (nonspecific) |
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Term
| These proteins can be measured in the serum even days after an MI |
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Definition
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Term
| Which markers can be used to show an MI days after the incident |
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Definition
| cTroponin-I, cTroponin-T and LDH |
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Term
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Definition
| H & M are the subunits of this enzyme |
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Term
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Definition
| LDH-1 (H4), LDH-2 (H3M), LDH-3 (H2M2), LDH-4 (HM3), LDH-5 (M4) |
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Term
| The LDH isozymes that can be used as MI markers |
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Definition
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Term
| The LDH isozymes that can be used as hepatitis markers |
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Definition
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Term
| This is very important to pay attention to when using LDH markers for MIs |
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Definition
| The ratio between LDH-1:LDH-2 |
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Term
| The normal serum ratio show for LDH isozymes |
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Definition
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Term
| Liver fxn tests measure this |
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Definition
| Biliary-excretory ability is meaured by this test |
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Term
4 markers for liver damage |
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Definition
1. Alanine aminotransferase (ALT),
2. Aspartate aminotransferase (AST),
3. Alkaline phosphatase (ALP),
4. γ-glutamyltranspeptidase (GGT) |
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