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Teratogens
Teratogens and their effects on the fetus
20
Medical
Graduate
06/02/2012

Additional Medical Flashcards

 


 

Cards

Term
ACE Inhibitors
Definition
Renal Damage
Term
Alkylating Agents
Definition
Absence of digits, multiple anomalies
Term
Aminoglycosides
Definition

CN VIII toxicity

 

(A mean guy hit the baby in the ear)

Term
Carbamazepine
Definition

Neural tube defects, craniofacial defects,

Fingernail hypoplasia,

developmental delay, IUGR

 

Inhibits folate absorption

Term

Diethystilbestrol

(DES)

Definition
Vaginal clear cell adenocarcinoma
Term

Folate Antagonists 

(Methotrexate)

Definition
Neural Tube defects
Term
Lithium
Definition

Ebstein's Anomaly - Tricuspid Leaflets are displaced into right ventricle, hypoplastic right ventricle, tricuspid regurg or stenosis, patent foramen ovale (80%), Dilated Right Atrium, Widely split S2

 

Term
Phenytoin
Definition
Fetal Hydantoin syndrome: Microcephaly, dysmorphic craniofacial features, hypoplastic nails and distal phalanges, cardiac defects, IUGR, mental retardation
Term
Tetracyclines
Definition
Discolored Teeth
Term
Thalidomide
Definition
Limb defects "flipper" Limbs
Term
Valproate
Definition
Inhinition of maternal folate absorption - neural tube defects
Term

Warfarin

 

Do not wage Warfare on the baby; keep it heppy with heparin (does not cross the placenta)

Definition
Bone deformities, fetal hemorrhage, abortion, ophthalmologic abnormalities
Term
Alcohol
Definition
Leading cause of birth defects and mental retardation
Term
Cocaine
Definition
Abnormal fetal deelopment and fetal addiction, placental abruption
Term
Smoking
Definition
Preterm labor, placental problems, IUGR, ADHD
Term
Iodide (lack or excess)
Definition
Congenital goiter or hypothroidism
Term
Maternal Diabetes
Definition
Caudal regression syndrome (anal atresia to sirenomelia), congenital heart defects, neural tube defects, macrosomia, Hypoglycemia, transposition of great vessels, failure to progress
Term
Vitamin A excess
Definition
Extremely high risk for spontaneous abortions a nd birth defects (cleft palate, cardiac abnormalities), Alters HOX genes
Term
X-rays
Definition
Microcephaly, mental retardation
Term
Phenobarbital (antiepleptic)
Definition
Pegnancy category D and should only be used in emergency situations when no other options are available
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