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Temperature Regulation and Exercise Physiology
Test 3
133
Physiology
Graduate
07/22/2011

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Term
These generate their own internal body heat and do not rely on the energy of sunlight in this regard.
Definition
Endotherms
Term
These are capable of maintaining body temp within narrow limits despite wide fluctuations in ambient temps. Humans fall into this category.
Definition
Homeotherms
Term
Large core temperature elevations can cause what 2 things?
Definition
Nerve malfunction
Protein denaturation
Term
The absolute limit for survival
Definition
106 degrees F
(21 degrees C)
Term
Core body temperature remains very constant, within 1 degree F, except when a person develops a febrile illness. A nude person can be exposed to dry air temps from _ to _ and still maintain an almost contant body temp
Definition
55 to 130 degrees F
Term
Oral temperature normal values
Definition
97-99.5 degrees F
.5 - 1 C less than rectal
Term
An estimate of internal temperature (core body temp): 98-98.6 degrees F
Definition
Rectal Temperature
Term
Internal temperature varies several degrees in response to what 2 things?
Definition
Activity patterns
Changes in external temps
Term
Circadian fluctuation of about 1 degree C, _ during the night and _ during the day
Definition
Lowest
Highest
Term
Women experience a higher body temp during when?
Definition
2nd half of menstrual cycle due to effects of progesterone
Term
Heat loss =
Definition
heat production
Term
When the rate of heat production in the body is greater than the rate at which heat is being lost, heat builds up in the body and body temperature __
Definition
Rises
Term
When heat loss is greater than the rate of heat production in the body, body temperature __
Definition
Decreases
Term
The process by which surfaces of all objects constantly emit heat in the form of electromagnetic waves.
Definition
Radiation
Term
The rate of emission is determined by teperature of the radiating surface; if body is warmer than various surfaces in the environment, net heat is lost from the body.
Definition
Radiation
Term
The rate of emission is dependent upon temperature difference. The body can gain heat by absorbing electromagnetic energy emitted by the sun.
Definition
Radiation
Term
A loss of gain of heat by transfer of thermal energy during collisions between adjacent molecules. Body surface loses or gains heat by __ through direct contact with cooler or warmer substances, including air and water.
Definition
Conduction
Term
__ is a better conductor than air so more heat is lost from the body in _ than air.
Definition
Water (for both)
Term
__ is not a perfect insulator so temperature is between the external environment and core.
Definition
Skin
Term
Functions as a variable regulator of heat exchange in blood flow. The more blood reaches it from the core, the more closely it's temperature approaches that of the core. Blood vessels can carry heat to it to be lost to the external environment.
Definition
Skin
Term
Name 3 behavioral mechanisms for altering heat loss
Definition
1. Changes in surface area
2. Changes in clothing
3. Choice of surroundings
Term
The amount of energy it takes to change temperature
Definition
Specific heat
Term
Conductive heat loss or gain is aided by movement of the air or water next to the body
Definition
Convection
Term
Give an example of convection
Definition
Air next to the body is heated by conduction
Term
Warm air is less dense, rises, heat is carried away from the body, cool air replaces it, follows the same pattern
Definition
Convection
Term
Aids conduction by continuously maintaining cool air
Definition
Convection
Term
Explain the cooling effect of wind
Definition
When body is exposed o wind, the layer of air immediately next to the skin is replaced by new air more rapidly than normal and heat loss by convection increases accordingly
Term
Water has a specific heat __ than air
Definition
Greater
Term
Water adjacent to skin can absorb __ quantities of heat than air
Definition
Greater
Term
__ __ in water is greater than air so it is impossible for the body to heat a thin layer of water next to the body to form an "insulator zone" as occurs in the air.
Definition
Heat conductivity
Term
Rate of heat loss to water is usually many times greater than the rate of heat loss to __
Definition
Air
Term
Clothing entraps air next to skin in the weave of cloth, thereby increasing thickness of __ __ of air adjacent to skin and also decreasing he flow of convection air currents; rate of heat loss from the body is greatly depressed.
Definition
Private Zone
Term
The effectiveness of clothing is almost completely lost when it becomes wet because the high conductivity of water increases the rate of heat transmission thru cloth __ fold or more
Definition
20
Term
__ of water from skin and membranes lining respiratory tract causes loss of body heat
Definition
Evaporation
Term
As long as skin temperature is greater than the temperature of the surroundings, heat can be lost by what 2 mechanisms?
Definition
Radiation
Conduction
Term
When the temperature of the surroundings becomes greater than that of the skin, the only means by which the body can rid itself of heat is by __
Definition
evaporation
Term
__ is required to transform water from liquid to gas, the heat required is conducted from surface and cools it
Definition
Energy
Term
Insensible water loss: Passive water loss occurs in 2 ways.
Definition
1. Loss of water by diffusion thru skin, even in absence of sweating
2. Loss from the respiratry lining during expiration
Term
Requires active secretion of fluid by sweat glands and its extrusion into ducts that carry it to the skin surface
Definition
Sweating
Term
Production of sweat stimulated by sympathetic nerves to glands. Sweat must evaporate in order to exert its cooling effect. Evaporation rate determined by the water vapor concentration of the air which is known as __
Definition
Humidity
Term
If you increase humidity, then you __ evaporation of sweat
Definition
Decrease
Term
The principle by-product of metabolism
Definition
heat
Term
Name 5 factors that determine the rate of heat production
Definition
1. Basal rate of metabolism of all the cells of the body
2. Extra rate of metabolism caused by ms activity, including ms contractions caused by shivering
3. Extra metabolism caused by the effect of thyroxine on the cells, epinephrine, NE, and symp stimulation of cells
4. Extra metabolism needed for digestion, absorption, and food storage
5. Extra metabolism caused by increased chemical activity in the cells themselves
Term
Rate of heat loss is determined by what 2 things?
Definition
1. How rapidly heat can be conducted from where it is produced in the body core to the skin
2. How rapidly heat can be transferred from the skin to the surroundings
Term
Continuously disrupted by metabolic rate or changes in the external environment
Definition
Body temp
Term
Body temperature is almost entirely regulated by what?
Definition
Nervous feedback mechanisms
Term
Almost all nervous feedback mechanisms operate thru temperature-regulating centers located where?
Definition
Hypothalamus
Term
Detect change and initiate reflexes that restore temp to normal.
Definition
Thermoreceptors
Term
Provided by sympathetic nerves to the sweat glands, skin arterioles, adrenal medulla, and motor neurons to skeletal muscles.
Definition
Output to reflexes initiated by thermoreceptors
Term
Found in the skin and provide feedforward information
Definition
Peripheral Thermoreceptors
Term
__ receptors in the skin respond to cold or warmth
Definition
Sensory
Term
There are __X cold receptors as their are warmth receptors. Therefore, peripheral detection of temperature mainly concerns the detection of cool or cold temps instead of warm
Definition
10
Term
When skin is chilled, immediate reflex effects are invoked and begin to increase body temp in what 3 ways?
Definition
1. Providing strong stimulus to begin shivering
2. Inhibiting the process of sweating if already occurring
3. Promoting skin vasoconstriction to diminish loss of heat thru the skin
Term
Shivering _ heat production
Definition
Increases
Term
Sweating and skin vasoconstriction __ heat loss
Definition
Decreases
Term
Provides essential feedback component of the reflexes.
Definition
Central Thermoreceptors
Term
Primarily found in the spinal cord, abdominal viscera, and the great veins of upper abdomen and thorax
Definition
Deep body temp receptors
Term
Exposed to core body temp, not surface temp
Definition
Central Thermoreceptors
Term
The primary integrator of reflexes for body temp
Definition
Hypothalamus
Term
Both skin and deep receptors are likely most concerned with preventing what?
Definition
Hypothermia
Term
"heat sensing" and "cold sensing" neurons are located in the ___ area and function as temperature sensors.
Definition
Pre-optic
Term
Both types of neurons (heat and cold sensing) increase their __ __ when the core temp changes - either increase temp (heat sensing)or decrease temp (cold sensing)
Definition
Firing Rate
Term
When the __ area is heated, skin all over the body breaks out in sweat, whereas the skin blood vessels dilate. This is an immediate reaction and excess body heat is inhibited.
Definition
Preoptic
Term
The mediator for the temp-sensing neurons
Definition
Posterior Hypothalamus
Term
Integrates the central and peripheral temperature sensory signals from thermoreceptors
Definition
Posterior hypothalamus
Term
Sensory signals from thermoreceptors and the anterior preoptic area stimulate the posterior hypothalamus at the level of the what?
Definition
Mammillary bodies
Term
At the level of the __ __, the signals are combined and processed to control heat-conserving and heat-producing reactions in the body.
Definition
Mamillary bodies
Term
Can increase heat loss or decrease heat production
Definition
Temp-decreasing mechanism
Term
Vasodilation of skin blood vessels in most areas of the body are caused by what?
Definition
Inhibition of sympathetic centers in the posterior hypothalamus that cause vasoconstriction
Term
Name 3 temp-decreasing mechanisms
Definition
1. Vasodilation
2. Sweating
3. Decrease in heat production
Term
Can decrease heat loss or increase heat production
Definition
Temp incrasing mechanism
Term
Caused by stimulation of the posterior hypothalamic sympathetic centers
Definition
Skin vasoconstriction throughout the body
Term
Sympathetic stimulation causes the arrector pili muscles attached to hair follicles to contract, bringing the hair upright. This allows them to trap a thick layer of "insulator air" next to the skin, so transfer of heat is depressed.
Definition
Piloerection
Term
Name 3 ways to increase thermogenesis
Definition
1. Hypothalamic Stimulation of shivering
2. Sympathetic "chemical excitation of heat production"
3. Increased thyroxine output
Term
An area called the __ __ center controls shivering
Definition
Primary Motor
Term
Normally inhibited by signals of heat from the anterior pre-optic area, but is excited by cold signals from the skin and spinal cord.
Definition
Shivering
Term
Caused by increased tone of skeletal muscle throughout the body by facilitating activity of ventral motor neurons. When the tone rises above a certain threshold, shaking of the muscle begins
Definition
Shivering
Term
During shivering, efferent motor nerves to skeletal muscle are influenced by the hypothalamus, no external work is performed, virtually all the energy liberated by the metabolic machinery appears as internal heat.This process is called what?
Definition
Shivering Thermogenesis
Term
An increase in metabolic activity caused by an increased adrenal secretion of epi and increase sympathetic activity to adipose tissue, some contribution by thyroid hormone. Minimal, rarely present in adults. Occurs in infants whose shivering mechanism less efficient; product is heat.
Definition
Nonshivering Thermogenesis
Term
Seen in newborn infants. Tissue is responsive to thyroid hormone, epi and SNS; contains large amounts of uncoupling proteins. Proteins uncouple oxidation from phosphorylation and make metabolism less efficient; product is heat.
Definition
Brown Adipose Tissue
Term
Cooling of anterior pre-optic area also increased production of what?
Definition
Thyrotropin Releasing Hormone (TRH)
Term
Where is TRH released from?
Definition
Hypothalamus
Term
TRH stimulates the release of what from the anterior pituitary gland?
Definition
TSH (Thyroid Stimulating Hormone)
Term
TSH stimulates the release of what by the thyroid gland?
Definition
Thyroxine
Term
What increases the rate of cellular metabolism throughout the body
Definition
Thyroxine
Term
An overactive thyroid gland, increses cellular metabolism and __ weight
Definition
Lose
Term
Is thyroxine output an immediate effect?
Definition
No, it requires several weeks of exposure to cold temps to make the thyroid gland hypertrophy and reach its new level of thyroxine secretion
Term
__ mechanisms regulating temp is a graded, progressive increase or decrease in activity
Definition
Effector
Term
Range of environmental temp (25-30 C) that blood flow alone can regulate. A person's ability to tolerate such temps above and below is determined by the humidity and by his or her maximal sweating rate.
Definition
Thermoneutral Zone
Term
Changes in sweating onset, volume, and composition determine the ability to adapt to chronic high temps.
Definition
Temp Acclimatization
Term
An important change in the composition of sweat with temp acclimatization, namely, a significant reduction in salt concentration due to incresed secretion of aldosterone.
Definition
Temp Acclimatization
Term
Body temp that is above normal range. Can be caused by abnormalities in the brain itself or by toxic substances that affect the temp-regulating centers
Definition
Fever
Term
Name 3 main causes of fever.
Definition
1. Temp regulation seriously impaired (106-114 F)
2. Heat stroke, brain lesion (105-116 F)
3. Febrile disease and hard exercise (99-104 F)
Term
Proteins, protein products, and other substances released from bacterial cell membranes can cause the set-point of the hypothalamic thermostat to rise
Definition
Pyrogens
Term
When set-point of hypothalamic temp-regulating center becomes __ than normal, all mechanisms for raising body emp are brought into play, within a few hours, the body temp approached the new level
Definition
Higher
Term
__ released from bacteria pyrogens increase temp-regulating set-point.
Definition
Endotoxins
Term
Leukocytes, macrophages, and lymphocytes digest bacteria and release what?
Definition
Cytokines
Term
Interleukin-1 is a cytokine released and immediately activates the processes to produce fever when it reaches the hypothalamus; it can increase in ___ minutes
Definition
8-10
Term
Can a hypothalamic tumor cause sever fever?
Definition
Yes
Term
When set-point of hypothalamic temp-control center is suddenly increased, body temp usually takes several hours to reach what?
Definition
The new temp set-point
Term
When the blood temp is less than the set-point which causes usual response to __ body temp
Definition
Elevate
Term
Duing the period when blood temp is less than set-point, the person experiences ___ and feels extremely cold even thogh his body temp may already be above normal.
Definition
Chills
Term
When a person has chills, their skin becomes cold because of __ and shivering occurs.
Definition
Vasoconstriction
Term
__ continues until the body temp reaches the hypothalamic set-point, the person no longer feels cold or hot.
Definition
Chills
Term
The factor that is causing the high temp it removed, set point of hypothalamic temp controller will be reduced
Definition
Crisis or "Flush"
Term
Body temp is still high but the hypothalamus is attempting to regulate the temp to 98.6 F. This causes intense sweating and sudden development of hot skin becasue of vasodilation everywhere.
Definition
Crisis or "flush"
Term
The upper limit of air temp that one can stand depends to a great extent on whether the air is dry to wet. If dry and sufficient, convection air currents are flowing to promote rapid evaporation from body, a person can withstand several hours of air temp at 130 F. If air is 100% humidified or if the body is in water, body temp rises whenever the environmental temp rises above 94 F.
Definition
Heatstroke
Term
When the body temperature rises into range of 105-108 F, person develops __
Definition
Heatstroke
Term
What are the symptoms of heatstroke?
Definition
Dizziness
Abdominal Distress
Vomiting
Delirium
Loss of consciousness
Term
Symptoms of a heatstroke often exacerbate by a degree of __ __ from fluid and electrolyte loss in sweat.
Definition
Circulatory Shock
Term
Abnormally high fever. Itself it is also damaging to body tissues, especially brain. Even a few minutes of very high body temp can be fatal. Immediate treatment of heatstroke by placing person in cold water bath is recommended.
Definition
Hyperpyrexia
Term
A person exposed to ice water for 20-30 minutes ordinarily dies because of heart standstill or fibrillation. Internal body temp will fall to about __F. If warmed rapidly by external heat, can be saved.
Definition
77
Term
Once body temp falls below __F, hypothalamus losses abililty to regulate temp; it is greatly impaired even at __F.
Definition
85
94
Term
__ heat production in each cell is depressed almost 2-fold for each 10degrees F decrease in body temp; sleepiness and coma can develop which depresses acivity of CNS heat control mechanisms and shivering.
Definition
Chemical
Term
Freezing of body surfaces
Definition
Frostbite
Term
Can cause extensive formation of ice crystals in the cells resulting in permanent circulatory damage.
Definition
Freezing
Term
Upon thawing __ can occurs and amputation may be necessary.
Definition
Gangrene
Term
Temp close to freezing paralyzes smooth ms in vascular wall and sudden __ occurs.
Definition
Vasoconstriction
Term
Can help prevent frostbite by delivering warm blood to the skin, mechanism not developed well in humans.
Definition
Paralysis of smooth ms and sudden vasodilation
Term
Administration of strong sedative to depress reactivity of hypothalamic temp controller and then cooling the person with ice or cooling blankets until the temp falls
Definition
Artificial Hypothermia
Term
Can be maintained below 90F for days to weeks. Used during heart surgery so the heart can be stopped artificially for many minutes at a time, will greatly depress cell metabolism so the cells can survive 30 minutes to more than 1 hour without blood flow during the surgical procedure.
Definition
Artificial Hypothermia
Term
Almost all energy released by metabolism of nutrients is eventually converted into body heat during:
Definition
Conversion of nutrient energy to ms work
Term
3 ways in which you can have conversion of nutrient energy into ms work.
Definition
1. Overcoming viscous resistance to the movement of ms and joints
2. Ovecoming friction of the blood flowing thru the vessels
3. Other effects which convert ms contractile energy into heat
Term
__ consumption by the body can increase in a well-trained athelete
Definition
O2
Term
The amount of heat liberated in the body is almost exactly proportional to what?
Definition
O2 consumption
Term
Tremendous amounts of heat injected into internal body tissues when performing endurance athletic events. During a hot and humid day a __ can easily develop in the athlete.
Definition
heatstroke
Term
In 1 hour of exercise as much as __ lbs of weight loss can occur due to sweat
Definition
5-10
Term
A __% decrease in body weight decreases performance and __% decrease in body weight can cause muscle cramps and nausea. It is essential to replace the fluids lost
Definition
3%
5-10%
Term
Name 3 things that sweat contains
Definition
Na
Cl
K
Term
If a person acclimates to the heat by progressiv increase in athletic exposure over a period of 1-2 weeks, what other 2 things acclimate?
Definition
Sweat glands
Salt Loss
Term
__ __ acclimation is due to increased aldosterone secretion by the arenal cortex. Aldosterone increases reabsoption of sodium chloride from the sweat before it is secreted onto the skin.
Definition
Sweat Gland
Term
__ loss results from increased secretion of aldosterone during heat acclimatization, which increases loss of potassium in the urine
Definition
K
Term
Supplemental fluids contain properly proportioned amount of what 2 things?
Definition
K
Na
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