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Taylor
Skin diagnoses
95
Health Care
Undergraduate 1
01/31/2011

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Term
Erosion
Definition
loss of superficial epidermis
Depressed, moist, glistening
Follows rupture of vesicle or bulla
Heals without scarring
Term
Ulcer
Definition
deeper loss of both epidermis and even into dermis
Concave
Varies in size
Decubitus bed sore, stasis ulcers
Term
Fissure
Definition
Linear or vertical crack/split in the epidermis to the dermis
Moist or dry
Athlete’s foot, corner of the mouth
Term
Crust
Definition
Dried serum (yellow/brown), blood (black/red), purulent (yellow, yellow-green) exudates
Various sizes
Brown, red, black, tan, straw-colored
scab of sore
Term
Scale
Definition
Heaped-up keratinized cells
Flacky skin
Irregular
Thick or thin
Varies in size
Term
Excoriation
Definition
Linear erosion (hollowing out) of epidermis
Crusted
Abrasion or scratch
Scabies
Term
Scar
Definition
Thin to thick fibrous tissue that replaces normal skin following injury or laceration to the dermis
Collection of new fibrous connective tissue
Term
Keloid
Definition
Irregular-shaped, elevated, progressively enlarging scar
Grows beyond boundaries of the wound
Caused by extensive collagen formation during healing
Term
Lichenfication
Definition
Rough, thickened epidermis 2° persistent rubbing, itching, skin irritation
Often involves flexor surfaces of extremities
Term
Hyperkeratosis
Definition
Abnormal skin thickening of the superficial layer of the epidermis
Term
Striae
Definition
Thinning of the skin surface and loss of skin margins
Skin becomes translucent and paper-like
Atrophy
Stretch marks
Term
Erythema
Definition
Redness
Indicates inflammation 2° to increased blood flow to area
cellulitis, rosacea
Term
Violaceous
Definition
Purplish color
Purpura, Kaposi’s Sarcoma
Term
Pallor
Definition
decreased redness due to lack of oxyhemoglobin
Best seen where the horny layer of the epidermis is the thinnest
Fingernails
Lips
mucosal membranes
palpebral conjunctiva
Assoiated with
Anemia
arterial insufficiciency\
h/o fainting
Term
Cyanosis
Definition
Bluish skin/mucous membranes
consistent with decreased oxygenation of blood
Central:
severe lung disease, heart disease
Peripheral:
venous obstruction
Term
Yellowing
Definition
Jaundice/Icterus
sclera affected first, palpebral conjunctiva, under tongue
**Liver disease
Carotonemia
Involves palms, soles, face but spares sclera
Term
Hyperpigmentation
Definition
Skin is darker than normal
tan, melasma, post-inflammatory change from light to dark
Term
Hypopigmentation
Definition
Skin is lighter than normal
post-inflammatory change from dark to light
Term
Depigmentation
Definition
Absence of any pigment
vitiligo, albino
Term
Annular
Definition
Ring-Shaped
Term
arcuate
Definition
Partial rings
Syphillis
Term
Bizarre
Definition
Irregular or geographic
Factitial dermatits
Term
Circinate
Definition
Circular
Term
Confluent
Definition
Lesions run together
Term
Discoid
Definition
disc shaped
Term
eczematoid
Definition
inflammatory with a tendecy to vesiculate and crust
Term
Skin exam what to look at
Definition
Texture- rough/smooth
Thickness- atrophy, aging, thinning
Temperature- warm of cool
Mobility and turgor- elastic, ease of moving lesion
Term
Patterns of Arrangement
Definition
Grouped and disseminated
Linear, Gyrate, Annular, Arcuate, Serpiginous, Reticulated, Discrete, confluent, nunmular/discoid, bull's-eye, dermatoma
Term
Serpiginous
Definition
Snakelike
Term
reticular
Definition
Fine or lace-like pattern
Term
Coalesced
Definition
in a cluster of group
herpes simplex
Term
Nynmular
Definition
Circular or coin shaped
Exzema
Term
Target/Iris Bull's eye
Definition
Rings wit central duskiness
Erythema multiforme
Term
Dermatomal
Definition
Follows distribution of a nerve
Herpetiform or zosteriform
Term
Patterns of distribution
Definition
Truncal (torso/back)
Dermatitis, Tinea
Acne
Cancer
Extensor (knee/elbow)
psoriasis
Flexor
atopic dermatitis
Photodistributed (sun-exposed)
cancer
Extremities
ulcers, cancer
Intertriginous (skin folds)
Candida, hidradinitis
Mucosal (eyes/mouth)
Face cancer, acne
Palms/soles fungal/tinea , warts
Term
Classification of lesions
Definition
Type of Lesion
Color
Location/distribution
Arrangement/ shape/pattern
Texture
Size
Term
Evaluation of Nails
Definition
Shape
Color
Surface irregularities
Abnormalities of specific structures
Term
Clubbing Nails
Definition
Increased angulation, curvature of the nail, and floating nail root
Idiopathic
COPD
Lung DZ
Malabsorption
Cirrhosis
Term
Spoon Nails (Koilnychia)
Definition
Spoon-shaped deformity
Normal in infants; resolves after first few years of life
Results from
Trauma
Recurrent exposure to petroleum-based solvents
Raynaud's Disease or Lupus
Iron Deficiency / Hemochromatosis
Term
Onycholyis
Definition
Literally means “loosening of the nail” in Greek
Separation of nail plate from nail bed
Begins at free edge and proceeds proximally
Causes include:
Trauma
Onychomycosis
Psoriasis
Thyrotoxicosis (Plummer’s nails)
Term
Nail Pitting
Definition
Nails are pocked by multiple tiny depressions
May eventually cause the nail to crumble
Psoriasis, Chronic Dermatitis
Term
Anonychia
Definition
Absence of nail or nails
Often traumatic
If multiple can be genetic
Term
Reddy Nails
Definition
Longitudinal ridging
Can be a normal variant in patient >50 years old
Term
Psoriasis
Definition
Alopecia areata
Vitiligo
Atopic dermatitis
Term
Beau's Lines
Definition
Transverse grooves on the fingernails of patient recovering from a serious illness
Due to arrested growth of matrix
Term
Terry's Nails
Definition
Characterized by whitening of proximal 80% of nail
Older patients
Heart failure
Cirrhosis
DM
2 ° Subungual edema
Term
Mee's Lines
Definition
Transverse white lines distal to the cuticle
Cause include:
General illness
Poisonings
Term
Lindsay's Nails
Definition
Half-and-half nails
Proximal half = White
Distal half = Pink
Chronic Renal Failure
2° subungual edema
Term
Spliner Hemorrhages
Definition
Tiny and linear red hemorrhage
Extend from free margin of nail proximally
Trauma
Endocarditis
Term
Onychomyocosis
Definition
Tinea unguium(fungal nail infection)
Characterized by
Hypertropy of the nail plate
Onycholysis
Dystrophic changes: yellowing of the nails
Term
Paranychia
Definition
Inflammation of perionychium
Redness
Edema
Painful / tenderness
Term
Aids for dermatologic Diagnosis
Definition
Skin exposure
Good lighting
Magnification
KOH prep
Tzanck Smear
Gram’s stain
Scabies prep
Skin biopsy
Term
KOH prep
Definition
Used for microscopic eval of scrapings
Used to detect fungal hyphae
KOH dissolves stratum corneum
Add scrapings & KOH and heat (if necessary
Term
Diascopy
Definition
A test for assessing blanchability of cutaneous lesion
Performed by simply applying pressure with a finger or glass slide and observing color changes to determine if redness is due to:
Erythema (capillary dilation)

Vasculitis (extravasation of blood)
areas of blood extravasation will not blanch
Term
Tzanck Smear
Definition
Standard used to detect Herpes Simplex and
Herpes Zoster
Base of vesicle scraped and smeared on glass slide
Stained with Wright’s stain or Methylene blue
Diagnostic: the presence of multinucleated giant cells
Term
Wood's Lamp Exam
Definition
Ultraviolet black light
Used to detect fungal infections
In a darkened room, it reveals fungal infections as sharply marginated patches of bright blue-green
Term
Wound Cultures
Definition
Can be bacterial, viral, or fungal
Fungal is nail or skin scrapings placed in culture medium
Term
Punch Biopsy
Definition
rapid technique
Some are disposable
Circular
size specific
neat scar
+/- suture
Term
Shave Biopsy
Definition
scalpel or razor blade
Term
Excisional Biopsy
Definition
removes entire lesion
Term
Incisional Biopsy
Definition
does not remove entire lesion; provide entry to an area
Term
SkinFunction
Definition
Mechanical barrier between the body and outside world
Protects the body from infection & injury and from UV rays
Body temperature regulation
Sensory organ providing sensation for
Touch
Pressure
Pain
Temperature
Term
Stratum Corneum
Definition
Non-living, horny layer
Stratified layers of Keratincytes
Not found in mucous membranes
The Major Barrier
Term
Stratum Granulosum
Definition
Keratohyalin granules
Term
Stratum Basale
Definition
Contains keratin-forming cells
Melanocytes
Langerhans’ cells – found throughout epidermis
Merkel’s cells
Term
Contents of Dermis
Definition
Connective Tissue
Collagen fibers
Reticulin fibers
Elastin fibers
Cellular Elements
Fibroblasts – form collagen
Mast cells – contain histamine
Macrophages, Lymphocytes
Ground Substance
Amorphous matrix of proteins
Term
Subcutaneous
Definition
Fat layer
Contains:
Large blood vessels
Nerves
Lymphatics
Base of
hair follicles
sweat glands
Sebaceous glands
Serves as:
Insulation for retaining heat
Shock absorber
Term
Vellus Hair
Definition
Thin
Inconspicuous
relatively unpigmented
Term
Terminal Hair
Definition
Scalp, brow, extremities, pubic, axillae
coarser thicker
more conspicuous
typically pigmented
Term
Anagen Phase
Definition
Growing phase
x 2-5 yrs
85-90% of scalp hair
↓ with age/male pattern baldness
Term
Catagen Phase
Definition
Short transitional phase
Term
Telogen Phase
Definition
Resting phase
~ x 3 mos
Term
Primary Lesions
Definition
initial lesion, beginning of most skin diseases
Term
Secondary Lesions
Definition
subsequent lesions that develop during the evolutionary process of skin disease or are created by scratching or infection
Maybe the only type of lesion present
Term
Flat, non palpable lesions
Definition
Macule < 1 cm
Patch > 1 cm
Term
Macule
Definition
< 1 cm area of skin or mucous membrane
may have non-palpable, fine scale
i.e. freckle
Term
Patch
Definition
> 1 cm area of skin or mucous membranes
different color from surrounding tissue
May have non-palpable, fine scale
Term
Nodule
Definition
1 – 2 cm
Circumscribed, elevated, solid
Dermal or subdermal
Term
Papule
Definition
<1cm
discrete, solid, elevated, firm
circumscribed
Wart or elevated moles
Term
Tumor
Definition
>2cm
Larger version of nodule
Benign or malignant
Term
Plaque
Definition
>1cm
Elevated, firm, rough lesions
with flat top surface
**Surface area > height
Psoriasis, Seborrheic/actinic
keratoses
Term
Wheal
Definition
No size
Elevated, irregular-shaped
area of cutaneous edema
Solid, transient, variable diameter
Hives or whelts
Insect bites
PPD
Term
Vesicle
Definition
< 1 cm
Elevated, circumscribed
Superficial, not into dermis
Filled with serous fluid
Varicella
Herpes Zoster
Term
Postule
Definition
< 1 cm
Elevated, superficial
Vesicle filled with
purulent material (pus)
Acne
Impetigo
Term
Bullae
Definition
Vesicle that is > 1 cm
Blister
Pemphigous vulagaris
Term
Cyst
Definition
No size
Elevated, circumscribed, encapsulated lesion
Filled with liquid (purulent)
or semisolid substance that is surrounded by a membranous sac
Sebaceous cyst
Cystic acne
Term
Telengectasias
Definition
Visible, persistent, dilation of small
superficial cutaneous blood vessels
Rosacea Acne
Term
Spider Angioma
Definition
Bright red
Blanch with pressure to central area
faintly pulsatile
consists of a
central arteriole with slender projections resembling spider legs
Liver failure
Term
Capillary Hemangioma
Definition
Most commonly found on the
Face
Scalp
Back
chest
Usually gone by age ten
Term
Venous Spider
Definition
A.k.a. “SPIDER VEINS”
A dilated veins that form a spider like pattern
Larger and darker than spider angiomas (less red and more violaceous and blue)
2° to increased venous pressure
Term
Cherry Angioma
Definition
Bright red papule
1-3 mm in size
Sometimes surrounded by a pale halo
Usually found on trunk
Term
Ecchymoses
Definition
Discoloration of the skin or mucous membranes (bruise)
2°extravasation of blood with color change over time
characteristic transition of color ranging from blue-black, brown-yellow, or green
Term
Petechiae
Definition
Small 1-2 mm
non-blanchable purpuric macules
2° tiny hemorrhages
Term
Palpable Purpura
Definition
Raised/palpable
Red/violaceous
Skin or mucous membranes
Due to vascular inflammation in skin & extravasation of red blood cells
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