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Table 7-11
Paraneoplastic Syndomes
15
Medical
12th Grade
09/17/2011

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Term
Cushing syndrome
Definition
ENDOCRINOPATHIES

Small-cell carcinoma of lung
Pancreatic carcinoma
Neural tumors

ACTH or ACTH-like substance
Term
Syndrome of inappropriate antidiuretic hormone secretion
Definition
ENDOCRINOPATHIES

Small-cell carcinoma of lung; intracranial neoplasms

Antidiuretic hormone or atrial natriuretic hormones
Term
Hypercalcemia
Definition
ENDOCRINOPATHIES

Squamous cell carcinoma of lung
Breast carcinoma
Renal carcinoma
Adult T-cell leukemia/lymphoma

Parathyroid hormone–related protein (PTHRP), TGF-α, TNF, IL-1
Term
Hypoglycemia
Definition
ENDOCRINOPATHIES

Ovarian carcinoma
Fibrosarcoma
Other mesenchymal sarcomas

Insulin or insulin-like substance
Term
Carcinoid syndrome
Definition
ENDOCRINOPATHIES

Hepatocellular carcinoma
Bronchial adenoma (carcinoid)
Pancreatic carcinoma

Serotonin, bradykinin
Term
Polycythemia
Definition
ENDOCRINOPATHIES

Gastric carcinoma
Renal carcinoma
Cerebellar hemangioma
Hepatocellular carcinoma

Erythropoietin
Term
Myasthenia
Definition
NERVE AND MUSCLE SYNDROMES

Bronchogenic carcinoma

Immunological
Term
Disorders of the central and peripheral nervous system
Definition
NERVE AND MUSCLE SYNDROMES

Breast carcinoma
Term
Acanthosis nigricans
Definition
DERMATOLOGIC DISORDERS

Gastric carcinoma
Lung carcinoma
Uterine carcinoma

Immunological; secretion of epidermal growth factor
Term
Dermatomyositis
Definition
DERMATOLOGIC DISORDERS

Bronchogenic, breast carcinoma

Immunological
Term
Hypertrophic osteoarthropathy and clubbing of the fingers
Definition
OSSEOUS, ARTICULAR, AND SOFT-TISSUE CHANGES

Bronchogenic carcinoma

Unknown
Term
Venous thrombosis (Trousseau phenomenon)
Definition
VASCULAR AND HEMATOLOGIC CHANGES

Pancreatic carcinoma
Bronchogenic carcinoma
Other cancers

Tumor products (mucins that activate clotting)
Term
Nonbacterial thrombotic endocarditis
Definition
VASCULAR AND HEMATOLOGIC CHANGES

Advanced cancers

Hypercoagulability
Term
Red cell aplasia
Definition
VASCULAR AND HEMATOLOGIC CHANGES

Thymic neoplasms

Unknown
Term
Nephrotic syndrome
Definition
OTHERS

Various cancers

Tumor antigens, immune complexes
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