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systems pharm
phase 1 reactions
5
Agriculture
11th Grade
10/23/2011

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Term
FMO
Definition
-catalyze oxygenation of N, P, S
-many isoforms
-requires O2, NADPH, FAD
-in liver and lungs
Term
MAO
Definition
-mitochondrial enzyme
-adds O to monoamine
-endogenous substrates are neurotransmitters
Term
DAO
Definition
-adds O to diamine
-substrates include histamine and polyamines
Term
XO
Definition
-substrates are purines
-hypoxanthine to xanthine, to uric acid
-adds O to purines
Term
alcohol and aldehyde dehydrogenase
Definition
-non-specific enzymes in soluble fraction of liver
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