Term
|
Definition
-tx hypothyroidism
-SE hypersensitivity, osteopenia, pseudotumor cerebri, sz, CV events
-metabolism in liver and target tissues
-half life 6-10 days
-IM IV PO
-adequate gastric acidity required (PO) |
|
|
Term
|
Definition
-tx hypothyroidism (myxedema coma)
-t3
-half life 2.5 days |
|
|
Term
|
Definition
-perchlorate
-thiocyanate
-pertechnetate |
|
|
Term
|
Definition
-tx hyperthyroidism
-thioamine
-only inhibits thyroid peroxidase
-SE itchy rash, arthralgia, less prothrombin, inc bleeding
-rare agranulocytosis, hepatotox,, vasculitis
-hepatic metabolism
-half life 4-6 hrs (once daily dose) |
|
|
Term
|
Definition
-prototype thioamine
-also inhibits t4 to t3
-TID |
|
|
