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Systems 3
Pituitary hypothalamic drugs
13
Biology
Graduate
02/06/2013

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Cards

Term
oxytocin
Definition
-induces labor
-SE antiduiretic, uterine spasm, arrhythmia,
-SE (fetus) CNS damage/sz
-IV
Term
conivaptan
Definition
-mixed V1 and V2 vasopressin receptor antagonist
-tx SIADH
-IV
Term
tolvaptan
Definition
-V2 vasopressin receptor antagonist
-tx SIADH and HF too
-PO
Term
demeclocycline
Definition
-tx SIADH
-tetracycline antibiotic
-SE diabetes insipidus
Term
Li
Definition
-tx SIADH
-reduces aquaporin-2 expression
-SE diabetes insipidus
-rare
Term
desmopressin
Definition
-tx diabetes insipidus
-stimulates V2
-IV,SQ,IN,PO,SL
Term
somatropin
Definition
-recombinant HGH
-tx confirmed GH def
-SE intracranial HTN, neoplasam, pancreatitis
-IM, SQ
Term
mecasermin
Definition
tx GH def-recombinant IGF-1 -SE hypoglycemia, sz, slipped upper femoral epiphysis, intracranial HTN -SQ
Term
octreotide
Definition
-tx GH excess
-SRL (more potent and longer t1/2 than somatostatin)
-SE-glucose regulation changes, arrhythmia, bradycardia, gallstones
-LAR-IM/IV (monthly), SQ
Term
pasireotide
Definition
-investigational SRL
-inc specificity
Term
bromocroptine
Definition
-tx excess GH
-DA agonist
-PO
Term
pegvisomant
Definition
-tx excess GH
-GH receptor antagonist
-SE inc LFTs
-long half life
-SQ
-expensive
Term
cabergoline
Definition
-tx high PRL
-DA agonist
-SE arrythmia, MI, HF, pulmonary fibrosis
-PO
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