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Systemic Disease Endocrine Disease
OPTOM 215
32
Science
Professional
10/23/2012

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Term
intracrine
Definition
hormone acts WITHIN the cell type that produced it
Term
Which structure produces tropic hormones?
Definition
Pituitary Gland
Term
What is a congenital cause of Hypopituitarism?
Definition
Bardet-Biedl Syndrome - Congenital, AR inheritance (higher risk if parents related)
Term
This cause of hypopituitarism features polydactly, obesity, hypogonads, Nephropathy, nyctalopia, retinitis pigmentosa
Definition
Bardt Biedl Syndrome
Term
What is the optometrists role in Bardt Biedl sydrome?
Definition
Refer them to a nephrolgist and a retinal specialist.
Term
This slow growing tumor can cause Hypopituitarism
Definition
Craniopharyngioma
Term
This infiltrative disease can cause Hypopituitarism
Definition
Hemochromatosis
Term
This disease is more common in men and includes signs of skin color change, bronze diabetes, cirrhosis (excess iron absorption)
Definition
Hemochromatosis
Term
Name two Acidophilic Pituitary Adenomas and what do they cause?
Definition
Gigantism and Acromegaly cause Hyperpituitarism
Term
Struma
Definition
Another word for goiter- enlargement of thyroid
Term
90% of cases of hyperthyroidism are this autoimmune disease
Definition
Graves Disease
Term
This disease is the most common cause of proptosis in adults
Definition
Graves Disease
Term
Dalrymple Sign
Definition
Wide palpebral fissure (wide open eye) as seen in Graves Disease
Term
Stellwag Sign
Definition
Unblinking stare - as seen in Graves disease
Term
VonGraefe Sign
Definition
Eyelid lag with downward gaze
Term
What is NO SPECS and what is this describing?
Definition
No other signs/symptoms except Only lid retraction, Soft tissue involvement, Proptosis, EOM involvement, Corneal involvement, Sight loss from ON neuropathy

This is Graves Disease
Term
This cause of hypothyroidism may feature puffy eyelids and madarosis
Definition
Hashimoto's thyroidosis
Term
Cretinism
Definition
Congenital cause of hypothyroidism in children
Term
Myxedema
Definition
Hypothyroidism in adults
Term
What does PTH do.
Definition
Parathyroid Hormone - increase free blood calcium via 1) increase small intenstine absorption of Ca, 2) decrease renal excretion of Ca, 3) increase osteoclast activity
Term
What type of endocrine gland problem can cause hypocalcemia
Definition
Hypoparathyroidism
Term
Chvostek sign
Definition
Facial nerve induced twitch in Hypocalcemia / hypoparathyroidism
Term
Trousseaus Phenomenon
Definition
Carpel spasm with bp cuff put on (in hypocalcemia / hypoparthyroidism
Term
What is the main ocular effect of hypocalcemia? (Hypparathyroidism)
Definition
Posterior cataract
Term
What is Cushing's SYndrome
Definition
Benign pituitary adenoma causes Hypercotricolism
Term
What syndrome features moon face, obese upper body, weak skin, and secondary diabetes?
Definition
Hypercorticolism/ Cushing's Syndrome
Term
What is the majority of Pheochromocytma caused by?
Definition
Benign tumor in adrenal medulla (90%)
Term
Hypertensive retinopathy, OHN swelling (NOT papilledema) cotton wool spots, hard exudates are features of what adrenal issue?
Definition
Pheochromocytoma
Term
Name 3 causes of hypopituitarism - one congenital, one tumor, and one infiltrative
Definition
Bardt Beidl Syndrome, Craniopharyngioma, Hemachromatosis
Term
What does "Bones Stones Abdominal Grones, Psychic Moans, Fatigue Overtones" Refer to
Definition
Hypercalcemia / hyperparathyroidism
Term
Osteoporosis is a significant feature of this parathyroid issue
Definition
hypercalcemia/ hyperparthyroidism
Term
What are two Adrenal gland malfunctions?
Definition
Cushing's SYndrome (hypercorticolism), Pheochromocytoma (benign tumor in adrenal medulla)
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