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Structure and Function of Plasma Membrane
Cell biology: characteristics of the Plasma membrane in depth
17
Biology
Undergraduate 4
09/24/2009

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Term
What does the mitochondiral membrane have a high ratio of in comparison to RBCs
Definition
protein/lipid ratio
Term
What are 7 membrane functions
Definition
1. compartmentalization
2. scaffold for biochemical activites
3. Providing A selectivily permeable barrier
4. transporting solutes
5. Responding to external solutes
6. Intercellular interacino
7. Energy transduction
Term
What are the 3 types of membrane lipids
Definition
1. phosphoglycerides
2. Sphinolipids
3. cholesterol
Term
Phosphoglycerides
Definition
lipd with phosphate built on a glycerol backbone
Term
ARe phosphoglycerides triglycerides or diglycerides?
Definition
diglycerides
Term
What are the hydroxul groups of a phosphglyceride esterfied to?
Definition
2 to fatty acids
1. to a hydrophilic phosphate group which is linked to an additional group(PC, PE, PS, PI)
Term
what are the 4 main types of membrane phosphoglycerides?
Definition
1. phsophatidylcholine(PC)
2. phosphatidylehtanolamine(PE)
3. Phosphatidylserine(PS)
phosphatidyl inositol(PI)
Term
What is the head group on a phosphyglyceride?
Definition
the side groups(PE,PS,PI,PC) and the negativly charge phosphate its attached to= h20 soluble portion
Term
What are the charges of the head groups at physiological pH?
Definition
PS/PI= neg.
PC/PE= neutral
Term
What are teh characteristics of eh fatty acyl chains on the phosphoglycerides?
Definition
hydrophobic and 16-22 Cin lnegth. usually in a phosphoglyceride one FA chain is unsaturated and one saturated
Term
Whichi s more healthier? Saturated or unsaturated? where can it be found in our diet?
Definition
2 unstaurated FA are healier and in fish oil. Ex. EPA and DHA- incorporated into PE and PC(brain and retina)...also called omega3 fatty acids.....amphipathic character
Term
Shingolipids
Definition
derivitives of sphingosine=2 long hydrophobic hydorcarbon chains...and a hydrophilic region on the other. Similar in strx to phosphoglycerides.
Term
glycolipids
Definition
type of shpingolipids in which a carbohydrate is the hydrophilic region...play crucial roles in cell fxn.(esp. nervous system). also a role in infectious disease
Term
different types of glycolipids
Definition
1. cerebroside-simple sugar attached to ceramide (in particular galactose)...2. ganglioside=cluster of sugars attached
Term
How do cerebroside and ganglioside impact if lacking?
Definition
cerebroside= tremors/eventual peralisis
ganglioside=sever seizures/blindness
Term
Cholesterol
Definition
sterol= upt o50% of teh lipid mol in the plasma mem...absent from most plant and all bacterial cells...rings=flat/rigid=interfere with FA tail movements
Term
How doe celular mem. differ in characteristics of lipid composition
Definition
1. types of lipids...2. nature of head groups...3. species of FA chains.
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