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Stroke
lecture 10, part 2
66
Pathology
Graduate
07/31/2014

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Cards

Term
Stroke Syndrome: 1
Definition
middle cerebral artery
Term
Stroke Syndrome: 2
Definition
Vertebral artery and posterior inferior cerebeller artery
Term
Stroke Syndrome: 3
Definition
lacunar
Term
Middle Cerebral artery syndrome
Definition
blockage of an entire MCA branch
Term
Blockage of an entire MCA branch leads to what
Definition
contralateral loss of movement and sensaation
Term
contralateral loss of movement
Definition
hemiplegia
Term
contralateral loss of sensation
Definition
hemianesthesia
Term
Blackage to smaller brancesh of the MCA leads to what
Definition
partial syndromes, ie brachial
Term
Brachial syndrome would lead to what
Definition
weakness of the upper extremity
Term
The more proximal the embolus, the ____ the vessel affected, leading to more severe involvement
Definition
larger
Term
Vertebral Arty and Poseterior Infereior Cerebellar Artery Syndrome affects what
Definition
medulla and posterior/inferior cerebellum
Term
Medulla an dposterior/inferior cerebellum being affected by a stroke leads to what
Definition
Wallenberg's syndrome
Term
What are the s/s of wallenberg's syndrome
Definition
vertigo, nausea, dyshpagia, ipsilateral ataxia and clumsiness, ptosis, impiaired sensation in the ipsilateral face and contralateral toso and limbs
Term
what are lacunes
Definition
expanded fluid filled cavities that surround the small penetrating vessels
Term
lacunar syndrome
Definition
tissue damage due to coiled hypertesnive vessels causing lacunes
Term
Where are lacunes often found
Definition
deep areas in the brain
Term
Factors that affect reperfusion of blood vessels are: 1
Definition
formation of fibrin in the gray matter surrounding the occluded vessel
Term
Factors that affect reperfusion of blood vessels are: 2
Definition
platelet aggregation
Term
Factors that affect reperfusion of blood vessels are: 3
Definition
endothelial swelling
Term
Factors that affect reperfusion of blood vessels are: 4
Definition
vasospasm
Term
Factors that affect reperfusion of blood vessels are: 5
Definition
internal bleeding
Term
abnormal distenions of a local blood vessel at the vessel's bifurcation
Definition
berry aneurysm
Term
Which produces too much dopamine?
Definition
huntington's disease
Term
which produces too little dopamine
Definition
parkinson's disease
Term
Amyotrophic Lateral Sclerosis
Definition
Lou Gehrig's DIsease
Term
ALS
Definition
progressive motor neuron disease
Term
ALS affects what structures
Definition
anterior horn cells of the spinal cord as well as the corticospinal tracts
Term
ALS is characterized by what
Definition
degeneration and scarring of nervous tissue
Term
Degeneration and scarring of thse tissue is characteristic of ALS
Definition
motor neurons of the lateral aspect of the spinal cord, brain stem, cerebral cortex
Term
ALS pathophys: 1
Definition
degeneration of cortex's pyramidal cells and nearby premotor areas
Term
ALS Pathophys: 2
Definition
degeneration of sensory and temporal cortices
Term
ALS pathophys: 3
Definition
demyelination and degeneration of the lateral and ventral tracts of the spinal cord and brain stem
Term
ALS Histological Changes: 1
Definition
decreased RNA content
Term
ALS Histological Changes: 2
Definition
accumulation of lipids
Term
ALS Histological Changes: 3
Definition
axonal swelling
Term
ALS Histological Changes: 4
Definition
presence of lymphocytes
Term
As a result of the death of peripheral motor neurons in the brain and spinal cord what happens
Definition
denervation and muscle atrophy takes place
Term
Alzheimer's Causes: 1
Definition
advanced age
Term
Alzheimer's Causes: 2
Definition
genetic predisposition
Term
Alzheimer's Causes: 3
Definition
abnormal processing of amyloid
Term
Alzheimer's Causes: 4
Definition
link to vascular disease
Term
Alzheimer's Causes: 5
Definition
loss of neurons
Term
Alzheimer's Causes: 6
Definition
increased concentration of neurfibrillary tangles and senile amyloid plaques
Term
Huntingtons' is characterized by: 1
Definition
abnormal movement
Term
Huntingtons' is characterized by: 2
Definition
hyperkinesia
Term
Huntingtons' is characterized by: 3
Definition
personality changes
Term
Huntingtons' is characterized by: 4
Definition
dementia
Term
Huntington's chorea
Definition
choreic (involuntary random) movements
Term
HD clinical picture: 1
Definition
excessive restlessness of the arms and face
Term
Chorea can be increased by what
Definition
stress, mental concentration, complex motor tasks, walking
Term
The chorea can be enough at times to throw off the patients balance leading to what
Definition
falls
Term
As HD progresses
Definition
strength diminishes, tone increases, visual disturbances arise
Term
MS Clincial Picture: Initial symptoms
Definition
sensory changes and weakness
Term
What sensory changes are involved with MS initially
Definition
paresthesia, diploplia, visual blurring, impaired balance
Term
Common complaints of MS: 1
Definition
fatigue and weakness
Term
Common complaints of MS: 2
Definition
impaired cardiorespiratory function
Term
Common complaints of MS: 3
Definition
potential for skin breakdown
Term
People with MS complains of fatigue and weakness especially in which environment
Definition
warm
Term
Common signs of Parkinsons: 1
Definition
movement disorders
Term
Commons signs of Parkinsons: 2
Definition
inability to initiate and stop movement
Term
Common signs of parkinsons: 3
Definition
diffuciutly with walking, changing direction, ADLs
Term
What is one of the first signs noticed in regards to Parkinsons
Definition
pill rolling, resting tremor
Term
When is resting tremor more common
Definition
at rest or at times of stress
Term
Where can the tremors spread to
Definition
all 4 limbs as well as face and neck
Term
Rigidity starts in 1 extremity, then spread throughout via 1 of 2 methods
Definition
cog wheel, lead pipe
Term
What are other signs of Parkinsons
Definition
bradykinesia, akinesia, freezing, stooped posture, shhuffling gait
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