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Streptococcus
VM 607 Final
25
Veterinary Medicine
Professional
02/20/2012

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Cards

Term
Characteristics
Definition
Gram + cocci
facultative anaerobes
strictly fermentative
growth results in marked decrease in pH
form chains
Term
Disease
Definition
suppurative disease
opportunistic pathogen
Term
C-carbohydrate
Definition
cell wall polysaccharide
Term
M-protein
Definition
fibrils that inhibit phagocytosis by inhibiting C3 in complement cascade
Term
Lancefield Serological Typing
Definition
based on M-protein
Term
Lancefield Serological Grouping
Definition
based on C-carbohydrate
Groups B,C,D,G are animal pathogens
Term
Lancefield Grouping Mechanism
Definition
extract contains antibody against the specific C-carbohydrate
this antibody is specific for a group of pathogens (A-G)
see precipitation when it is positive
Term
Strep Virulence Factors
Definition
reason why more invasive than staph
Streptokinase
hyaluronidase
DNAse
produces thinner, spreading exudate instead of thick abscess like with staph
Term
Streptokinase
Definition
strep virulence factor
converts and activates plasminogen to become an active protease
digests fibrin clots and inhibits walling off
Term
Hyaluronidase
Definition
Strep virulence factor
digests connective tissues and aids in spread
Term
DNAse
Definition
Strep virulence factor
thins out thick, viscous deposits of DNA leaking out from lysed inflammatory cells
Term
Strep Damage
Definition
does not survive phagocytosis
produces streptolysins to lyse PMNs to increase inflammatory damage
Term
Streptococcus equi Disease
Definition
Strangles
Term
Streptococcus equi Transmission/Entry
Definition
from horse to horse
oral/nasal routes
ingestion of contaminated food/water
flies
survive in contaminated environment for 3-4 weeks
Term
Streptococcus equi Spread
Definition
adheres to epithelial cells
invades through mucosa
spreads through draining lymph nodes and causes abscesses in lymph nodes
Rupture lymph nodes drain into guttoral pouch and stays in there for along time
Pus can drain backwards through eustacean tube and into pharynx and out the nares
Term
Streptococcus equi Symptoms
Definition
anorexia, fever, inflammation of nasal mucosa, purulent discharge, intermandibular area becomes distended, noisy rapid breathing
Term
Streptococcus equi Diagnosis
Definition
can aspirate lymph node and Gram stain it
Term
Streptococcus equi Damage
Definition
damage and rupture of lymph nodes
can spread to thorax or abdomen - bastard strangles
Term
Purpura Hemorrhagica
Definition
caused by Streptococcus equi
non-contagious acute fatal allergic complication to M-protein
petechial hemorrhages, edema, purpura
Term
Streptococcus equi Vaccination
Definition
a lot of side effects
have to revaccinate every 6 months
Term
Streptococcus zooepidemicus Encounter
Definition
commensal in many species
most common cause of wound infections in hroses
secondary invader of upper respiratory infections in young horses
often follows Streptococcus equi
Term
Streptococcus agalactiae Disease
Definition
most common cause of bovine mastitis
Term
Streptococcus suis Encounter
Definition
opportunistic pathogen
overcrowing in cold weather and poor ventilation
zoonotic
Term
Streptococcus suis Disease
Definition
meningitis and septicemia in young pigs
Toxic Shock Syndrome
Term
Streptococcus porcinus Disease
Definition
swine strangles
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