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Step 1 Buzz Words
Words I have found that refer to specific pathology
121
Medical
Graduate
05/20/2010

Additional Medical Flashcards

 


 

Cards

Term
Pencil-in-cup
Definition
Psoriatic Arthritis
deformation of DIP joint
Term
Codman's Triangle
Definition
Osteosarcoma
Tumor lifting up the periosteum.
Term
Ferruginous Bodies
Definition
Asbestiosis
asbestos fibers covered in hemosiderin
Term
Keratin Pearls
Definition
Squamous Cell Carcinoma of the lung
Craniopharyngioma
Term
Kulchitsky Cells
Definition
Small cell Carcinoma of the lung
Term
Machinery Murmer
Definition
PDA
You'll see this in hypoxemic/premature baby
Term
Lamellar Bodies
Definition
Type II Pneumocytes
vesicles containing surfactant in type II pneumocytes visualized on EM
Term
Hyaline membranes
Definition
RDS, ARDS
Term
Stacatto Cough
Definition
C. Trachomatis Pneumonia
Fast small cough; in reference to a 2 wk old infant
Term
Mucoid Sputum
Definition
Klebsiella Pneum
Will see this in an alcoholic with high spiking fevers and productive cough of mucoid sputum
Term
Corona
Definition
Aspergillus
Term
Fungus Ball
Definition
Aspergillosis
Aspergillus inhabitating cavitary lesions of TB
Term
Ghon Complex
Definition
Primary TB
Term
Caplan Syndrome
Definition
Pneumoconiosis + Rheum nodules in the lung
Term
Potatoe Nodes
Definition
Sarcoidosis
Appearance of enlarged Hilar lymph nodes on an xray
Term
Boot Shaped Heart
Definition
Tetralogy of Fallot
Term
Notching of the Ribs
Definition
Coarctation of the aorta
Due to collateral circulation formation
Term
Onion Skinning
Definition
arteriolosclerosis
hyaline thickening of small arteris in essential HTN
Term
Disordered/tangled myocardial fibers
Definition
Hypertrophic Cardiomyopathy
Term
Roth Spots
Definition
Bacterial Endocarditis
Round white spots on retina surrounded by hemorrhage
Term
Janeway Lesions
Definition
Bacterial EndocarditisSmall erythemetous lesions on palms or soles
Term
Splinter Hemorrhages
Definition
Bacterial Endocarditis
Term
Osler's Nodes
Definition
Bacterial Endocarditis
Tender raised lesions on finger or toe pads
Term
Aschoff Bodies
Definition
Rheumatic Heart Dz
Granuloma with ginant cells in cardiac muscle
Term
Anitschkow's cells
Definition
Rheumatic Heart Dz
Activated histiocytes
Term
Bird's Beak
Definition
Achalasia
Appeareance of LES on a barium swallow.
Term
Mallory Bodies
Definition
Alcoholic Liver
Ubiquinated intermediate filaments (keratin) in an alcoholic liver; appear eosinophilic
Term
Heinz Bodies
Definition
G6PD Deficiency
Dark intracellular inclusions that stain with crystal violet seen in RBCs on peripheral smear. The inclusions are precipitated Hb molecules whose sulfhydryl groups are oxidized by stress and can't be reduced b/c of a deficiency in the enzyme that protects Hb from oxidative damage
Term
Chocolate Colored Blood
Definition
Methemoglobinemia
increased concentration of deoxyhemoglobin
Term
Dust Cells
Definition
Coal Worker's Pneumoconiosis
phagocytosis of anthracotic pigment of coal dust by alveoloar macrophages in coal miners
Term
Honey Colored Crust
Definition
Impetigo- S. Pyogenes
Term
Risus Sardonicus
Definition
C. Tetani
Lock-jaw associated with C. Tetani infx
Term
Eschar
Definition
B. Anthracis, Mucor, Rhizopus, Absidia
Necrotic tissue
Term
Chancre
Definition
primary syphilis
Painless ulcer
Term
Target lesion
Definition
Lyme Dz/B. Burgdorferi
Erythema Chronicus Migrans
Term
Chancroid
Definition
Haemophilus Ducreyi
Painful Ulcer on genitalia
Term
Rose Spots
Definition

Salmonella Typhi infx

Rash on abdomen (erythematous macules) in typhoid fever

 

Term
Crurrent Jelly Sputum
Definition
Klebsiella Pneum
Term
Caseous Granulomas
Definition
M. TB
Term
Pott's Dz
Definition
Secondary TB
Compression fractures in the vertebral bodies from M. TB seeding there in secondary TB
Term
Burton's Lines
Definition
Lead poisoning
lines on gingivae
Term
Gray Baby Syndrome
Definition
Chloramphenicol
Term
Cave exposure
Definition
1. rabies from bats
2. histoplasmosis
Term
Bullet Shaped Capsid
Definition
Rabies Virus
Term
Live Virus Vaccines
Definition
1. MMR
2. Polio
3. VZV
4. yellow fever
5. small pox
Term
Killed virus vaccines
Definition
1. rabies
2. influenza
3. Polio
4. Hep A
Term
Recombinant virus vaccines
Definition
1. Hep b
2. HPV
Term
Situs inversus
Definition
Kartagener's Syndrome
Term
Kulchitsky Cells
Definition
Small Cell/Oat cell carcinoma of the lung
small dark blue cells
Neuroendocrine tumor
Term
Cancer assoc. w/ hypercalcemia
Definition
1. Squamous cell carcinoma of the lung (PTHrP)
2. RCC
3. Breast carcinoma
Term
Cancer assoc. w/ SIADH
Definition
1. Small Cell/Oat Cell carcinoma of the lung
2. intracranial neoplasms
Term
Cancer assoc. w/ the development of Lambert-Eaton Syndrome
Definition
caused by production of auto-Ab to presynaptic Ca channels at NMJ 1. Small Cell/Oat Cell carcinoma of the lung
Term
Common location and manifestations of lung metastasis
Definition
1. liver (jaundice and hepatomegally)
2. brain (seizures)
3. bone (pathologic fx)
Term
Stimulate IgE production
Definition
IL-4
Term
Order of Ig Genes
Definition
M -> D -> G -> E -> A
Term
Stimulates IgA production
Definition
TGF-B
Term
Drug assoc. w/ ototoxicity
Definition
Aminoglycosides and Vancomycin
Term
drug assoc. w/ color blindness, central scotoma, and decreased visual acuity
Definition
Ethambutol
Term
Drug assoc. optic neuritis
Definition
ethambutol
Term
Drug assoc. w/ hearing and balance problems
Definition
Aminoglycosides and Vancomycin
Term
Drug assoc. w/ flaccid paralysis
Definition
Aminoglycosides
Term
Drug assoc. w/ acute tubular necrosis
Definition
Aminoglycosides
Term
drug(s) assoc w/ renal toxicity
Definition
Aminoglycosides and amphotericin B
Term
Shoulder pain, neck pain and pleuritic chest pain
Definition
Irritation of diphragmatic and mediastinal pleura
sensory information carried by Phrenic nerve (C3,4,5)
Term
T-cell dependent Ags
Definition
Ag containing protein component
Term
T-Cell independent Ags
Definition
Ag lacking a peptide component (cannot be presented by APC to a T-cell)
Term
Recurrent Staph infxs
Definition
CGD b/c susceptible to catalase positive bacteria
Term
Desmosin Crosslinking
Definition
Elastin
bonds formed b/w 4 elastin molecules and responsible for its durability
Term
Defect in fibrilin
Definition
Marfans Syndrome
Term
Nitroblue teraxolium test
Definition
positive in CGD = don't turn PMNs dark blue b/c of lack of NADPH oxidase
Term
Red orange bodily fluids
Definition
Rifampin
Term
Requires cholesterol in grow in Cx
Definition
Mycoplasma Spp.
Term
Activation of Eosinophils
Definition
IL-5
Term
Chemotactic factors
Definition
C5a, Leukotriene B4, 5-HETE (precursor to LTEB4)
Term
Optochin resistant
Definition
S. Veridans
Term
Beta hemolytic
Definition
GAS/S. Pyogenes
GBS/S. Agalactiae
Staph. Aureus
Term
Bacitracin Sensitive Strep
Definition
GAS/S. pyogenes
Term
Bacitracin resistant Strep
Definition
GBS/S. agalactiae
Term
bile sensitive strep
Definition
S. Pneumo
Term
Stimulates TH cells to differentiate into TH1 cells
Definition
IL-12, secreted by B cells and Macs
Term

Th1 cells

What do they secrete?

What do they do?

What inhibits them?

Definition
secrete IL-2 and IFN-gamma activates macs and CD8+ cells inhibited by IL-10
Term

Th2 cells

What do they secrete?

What do they do?

What turns them off?

Definition
Secrete IL-4, IL-5, IL-10 Help B cells make Ab (IgE > IgG) Inhibited by IFN-gamma (TH1)
Term
Spastic tetraparesis
Definition
Nieman-Pick and Lesch-Nyhan syndrome
Term
Cluster-Differentiation (CD) protein associated with T-cells
Definition
CD3
Term
IL-2 receptor + MHC II
Definition
CD4+ (Th) cell
Term
F(x) of IL-2
Definition
stimulate T cell proliferation
Term
Low levels of C4
Definition
Hereditary Angioedema
Lack of C1INH leads to constant breakdown of C4 and activation of classic compliment p'way
Term
SER
Definition
location of drug detox and steroid hormone synthesis
Term
Erythema Nodosum
Definition
1. Crohn's Dz
Term
Problems caused by Chagas Dz
Definition
Dilated cardiomyopathy 2o achalasia
Term
Type 1 muscle
Definition
Slow Twitch, red fibers
Term
enlarged tonge and umbilical hernia in an infant
Definition
congenital hypothyroid
Term
frequent neisserial infxs
Definition
deficiency in C5-C9
Term
SLE-like infx
Definition
drug-rxn
deficiency in C1, C3 and C4
Term
recurrent infxs by bact, fungi, viruses and opportunisitinc infx + FTT
Definition
SCID
Term
Gray, non-purulent vaginal d/c
Definition
gardinella vaginalis
Term
numerous squamous epith cells covered w/ adherent bact on wet mount of vaginal d/c
Definition

="clue cells"

Gardinella vaginalis

Term
purulent vaginal d/c
Definition
n. gonorrhea or chlamydia trachomatis
Term
maculopapular rash beginning on the face and spreading to the trunk and extremities in children
Definition
rubella (togavirus) or measles (rubeola, a paramyxovirus)
Term
rash + occipital or posterior auricular lymphadenopathy
Definition
rubella (togavirus)
Term
difference b/w rubella and measles in presentation
Definition
rubella has posterior auricular and occipital lymphadenopathy as well as the rash. Measles only has the rash
Term
injury to knee common to carpet layers, roofers and plumers
Definition
"House-maids" knee
Pre-patellar bursitis
Term
vasculitis of graft vessels
Definition
acute rejection
Term
fibrosis of graft stroma and BVs
Definition
chronic rejection
Term
skin, liver and intestine problems w/i one week of an organ transplant
Definition
GVH dz
Term
provides sensation b/w the 1st and 2nd toes
Definition
deep peroneal nerve
Term
URI followed by diarrhea
Definition
rotavirus
Term
Responsible for isotype switching from IgM -> IgE
Definition
IL-4
Term
Responsible for isotype switching from IgM -> IgA
Definition
IL-5
Term
Inhibits Th1 cells
Definition
IL-10
Term
Stimulates Th1
Definition
IL-12
Term
Chronic lymphedema puts someone at risk for what?
Definition
angiosarcoma
Term
Anti-mitochondrial Ab
Definition
Primary Biliary Cirrhosis
Term
CD 14
Definition
Monocyte-macrophage lineage
Term
CD 3
Definition
T-Cell marker
Term
CD 20
Definition
B-cell marker
Term
Proteinuria in a child following a URI and mechanism for protein loss
Definition
Minimal changed dz- caused by loss of anion barriers in GBM that allows the negatively charged albumin through
Term
Priapism as a Side Effect
Definition
Trazodone (inhibits uptake of serotonin)
Used for insomnia
Term
Life-long h/o gingival bleeding, epistaxis, mucosal bleeding and/or menorrhagia
Definition
vWF deficiency
Term
Diff b/w Orotic Aciduria and Ornithine Transcarbamoylase Deficiency
Definition

Orotic Adicuria: ↑ Orotic acid in urine (and megaloblastic anemia that doesn't improve w/ b12 or folic acid + FTT) and NO hyperammonemia

 

OTC deficiency: ↑ Orotic acid in urine + hyperammonemia

Term
Latex agglutination test
Definition
cryptococcus neoformans
tests for polysaccharide capsule Ag
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