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Spleen Pathology
for exam 3
44
Medical
Undergraduate 1
03/23/2011

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Term
amyloidosis
Definition
metabolic disorder by amyloid deposits in organs and tissue
Term
Gaucher's disease
Definition
fat and proteins are deposited abnormally in the body
Term
splenomegaly
Definition
enlargement of spleen
Term
Niemann-Pick Disease
Definition
predominantly infant females, inhereted, hepatomegaly, brain degression, uncordinated muscles, die by age 3
Term
RA, osteomyitis, multiple myeloma, TB, ankylosing spondylitis
Definition
Amyloidois
Term
Storage Disease
Definition
Amyloidosis, Gaucher's Disease, Niemann-Pick Disease
Term
Sickle Cell Anemia
Definition
inhereted as autosomal recessive trait, abnormality of globin genes in hemoglobin, crescent moon shaped blood cell, African descent, infarction
Term
Congenital Spherocytosis
Definition
spheriod or globe shape blood cell, splenomegaly, infarction
Term
Hemolytic Anemia
Definition
decreased life of erythrocytes, rate of destruction is greater than the bone marrow can compensate
Term
polycythemia vera
Definition
Chronic, involves bone marrow elements, increased blood cell mass and hemoglobin concentration
Term
Thalassemia
Definition
deficient synthesis of hemoglobin, target cells, short life span, splenomegaly fills entire abdomin, mediterranean and Asian descent
Term
myeloproliferative disorders
Definition
acute and chronic myelogenous leukemia, polycythemia vera, myelofibrosis, megakaryocytic leukemia, erythroleukemia, parenchyma is hypoechoic to liver
Term
granulocytopoietic abnormalities
Definition
hyperplasia resulting from acute or chronic infection, possible contaminated water source, bright echogenic lesions, calcium in splenic artery
Term
reticuloendotheliosis
Definition
isoechoic spleen, lipid storage in phagocytes
Term
letterer-siwe disease
Definition
children under 2 yrs old, hepatosplenomegaly, fever, rapidly fatal, splenic lymph nodes, bone marrow
Term
hand-schuller-christian disease
Definition
benign or chronic, children over age of 2, diabetes, moderate hepatosplenomegaly
Term
nonlipid reticuloendotheliosis
Definition
letterer-siwe disease
Term
lymphopoietic abnormalities
Definition
lymphocytic leukemia, lymphoma, hodgkin's disease
Term
chronic myelogenous leukemia
Definition
responsible for more extreme splenomegaly than any other disease. leukemia
Term
focal diseases
Definition
splenic abscess, infarctions, trauma, cysts, benign or malignant tumors
Term
splenic abscess
Definition
infection from distant foci in abdomen or inflammatory process extends directly for adjacent organs
Term
splenic infection
Definition
most prominent feature is splenomegaly
Term
 AIDS patients 
Definition
spenomegaly, multiple hypoechoic well defined focal lesions, lymphoma
Term
splenic infarction
Definition
most common cause of focal lesions caused by occlusions of splenic artery and branches. vegetation of left side heart valves.
Term
splenic trauma
Definition
RUQ pain, hematoma, blunt force to RUQ
Term
splenic cyst
Definition
parasitic or non parasitic, caused by trauma, infection, or infarction
Term
benign neoplasm
Definition
isoechoic compared to normal parachyms, hamartoma, cavernous hemangioma, cystic lymphangioma
Term
hamartoma
Definition
asymptomatic, solitary or multiple, well defined, not encapsulated, hyperechoic with solid and cystic components
Term
cavernous hemangioma
Definition
a large inhomogenous echogenic mass with multiple small hypoechoic areas
Term
malignant neoplasm
Definition
hemangiosarcoma, lymphoma, metastases
Term
hemangiosarcoma
Definition
rare, vascular endothelium of spleen
Term
lymphoma
Definition
diffuse involvemen, focal small nodular lesions, focal large nodular lesions, bulky disease
Term
metastases
Definition
hematogenous spread from another primary site, most common is melanoma (skin cancer)
Term
splenic cyst
Definition
[image]
Term
splenic infection
Definition
[image]
Term
splenic lymphoma
Definition
[image]
Term
splenic trauma
Definition
[image]
Term
splenomegaly 1
Definition
[image]
Term
splenomegaly
Definition
[image]
Term
splenic hamartoma
Definition
[image]
Term
splenic carvenous hemangioma
Definition
[image]
Term
hyperemia
Definition
unusual amount of blood in a part
Term
Niemann-Pick disease
Definition
female predominance, pt. dies by age three
Term
echinococus
Definition
parasite that forms cysts
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