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Sleep Neurobio Exam 2
Chervin Handout
20
Biology
Undergraduate 4
11/09/2010

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Term
Electrooculography
Definition
picks up the inherent voltage of the eye. The cornea has a positive voltage output, while the retina has negative polarity
Term
parameters for staging human sleep (electrode locations)
Definition
- L/R eye
- EEG leads ( frontal/central/occipital)
- EMG submental (chin area)
Term
Alpha Activity
Definition
resting, AWAKE, with eyes open
Frequency: 8.1012.0 Hz
Region: maximal over occipital cortex
Term
Theta Activity
Definition
When someone is slipping into sleep
Frequency: 4.1-8.0 Hz
Region: central vertex region
*most common sleep activity
Term
Delta Activity
Definition
During deep NREM sleep
Frequency: .5-4.0 Hz
Region: frontal
amplitude > 75mm
Term
Sleep spindles
Definition
generated by the thalamus
Frequency: 12-14 Hz
>.5 to 2-3 secs in duration
Indicative of stage 2 sleep
Term
K complexes
Definition
Sharp slow waves with negative then positive deflection.
must be at least .5secs
can occur from external stimulus
Term
stage 1 sleep
Definition
-slow rolling eye movements in the EOG channels
->50% of the epoch contains theta activity (3-7Hz)
-relatively high submental EMG tone
Term
stage 2 sleep
Definition
-mirrored EOG and EEG leads
-background EEG is theta (3-7Hz); k complexes and sleep spindles occur episodically
-High tonic submental EMG
Term
Stage 3 sleep
Definition
-EOG channels mirror delta activity (.5-4Hz)
-20-50% of epoch contains delta EEG activity
-submental muscle tone may be slightly reduced
Term
stage 4 sleep
Definition
-the EOG leads mirror all of the delta EEG activity
->50% of he epoch shows delta EEG activity
-submental EMG activity slightly reduced compared to light sleep
Term
REM sleep
Definition
-rapid eye movements (EOG leads)
-mixed frequency EEG
-low tonic submental EMG
Term
multiple sleep latency test
Definition
patients attempt to 5 naps during the day with 2hr intervals
-measure sleep latency and number of sleep-onset REM periods
Term
Insomnias
Definition
-adjustment insomnia (relative dies etc)
-pscyhophysiological (concern of sleep keeps u awake)
-inadequate sleep hygiene (common changes in sleep scheds)
-behavioaral insomnia of childhood
Term
sleep-disordered breathing (types)
Definition
-central sleep apnea(loss of drive to breathe)
-OSA
-sleep-related hypoventilation (can't move diaphragm enough)
Term
central hypersomnias
Definition
-narcolepsy (with/without cataplexy)
-reccurrent hypersomnia (sleep for 20hr, then normal for long time)
-idiopathic hypersomnia (long sleep time, otherwise normal)
Term
circadian rhythm disorders
Definition
-delayed sleep phase disorder
-free-running type
-jetlag disorder
-shift work disorder (shift sleep sched)
Term
parasomnias
Definition
-sleep walking/sleep terrors
-REM sleep behavior disorder (can show suspicion of parkinsons's)
-sleep enuresis
-sleep-related eating disorder
Term
movement disorders
Definition
-restless legs syndrome
-periodic limb movement (20sec intervals)
-bruxism
-rhythmic movement disorder (head banging/rocking)
Term
signs of sleep apnea
Definition
-obesity
-retrognathia (lower jack back)
-large tonsils
-large narrow face
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