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Skeletal Tissue
numerical breakdown, functions of tissue, fractures, histology,ossification, etc.
28
Anatomy
12th Grade
11/08/2007

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Term
osteoprogenitor cells
Definition
these are undifferentiated (unspecialized) cells that form mesenchymal tissue that have to become osteoblasts (new bone cells).
Term
osteoblasts
Definition
these are non-mitotic cells that secrete mineral salts and organic components
Term
osteocytes
Definition
these are non-mitotic. they are derived from osteoblasts. they are isolated in the matrix material (calcified bone). they are responsible for daily tissue operation.
Term
osteoclasts
Definition
these are bone destroying cells. they are found on the bone surfaces and are active in bone resorption. they are specialized phagocytic cells derived from white blood cells (monocytes) and are multinuclear
Term
tissue salts
Definition
calcium phosphate, calcium carbonate, plus, magnesium hydroxide, flouride, and sulfate
Term
1/3 bone weight
Definition
organic; osteoblasts, matrix, collagenous fibers
Term
2/3 bone weight
Definition
inorganic; calcium phosphate, calcium carbonate
Term
compact osseous tissue
Definition
has few large open spaces and is thicker in the diaphysis than the epiphyses
Term
lamellae
Definition
these are concentric rings of calcified (hard) intercellular substance
Term
compact bone has a _______ system
Definition
haversian
Term
lacuna(ae)
Definition
small, hallow spaces that contain osteocytes - these can't produce new bone tissue. but, maintain the mature tissue.
Term
canaliculi
Definition
minute, tiny canals that connect lacuna with the lamellae. they serve to bring nutrition to the bone tissue delivered from the bones' blood supply
Term
the function of compact bone
Definition
protection & support
Term
spongy (cancellous or soft) bone tissue
Definition
this tissue has large spaces filled with red marrow which is characteristic of short, flat, and irregular bone
Term
what does spongy tissue have instead of a haversian system?
Definition
a network of thin plates called trabeculae and large open spaces (lacunae) through which vessels nourish the marrow and bone
Term
skull bones have a specialized network of soft tissue called
Definition
diploe
Term
spongy bone is typical of the epiphyses of the ____, _____,____,___,____, and the ___ ____
Definition
long bones, pelvis, wrist, ankle, scapula, and the skull bones
Term
diaphysis
Definition
the shaft (long portion) of a bone
Term
epiphysis(es)
Definition
these are the end of the bone (proximal and distal)
Term
metaphysis
Definition
this is the area between the epiphysis and the diaphysis = the growth plates of the bone
Term
articular cartilage
Definition
is a thin layer of hyaline cartilage covering the distal and proximal epiphyses. it reduces friction and improves shock absorption of the bone.
Term
periosteum has _ layers
Definition
2 layers
Term
outer layer of the periosteum
Definition
(fibrous layer) contains the blood vessels, lymph vessels, and nerves
Term
inner layer of the periosteum
Definition
contains elastic fibers, blood vessels, and osteoprogenitor cells = osteogenic layer - osteoblasts and osteoclasts.
Term
medullary ("marrow") cavity
Definition
contains the yellow marrow (in adults) and fat cells for energy storage
Term
endosteum
Definition
a thin layer lining the marrow cavity of the diaphysis
Term
at birth you have ___ bones and as an adult you have ___ bones
Definition
275 bones, 206 bones
Term
endochondral ossification (hard bone)
Definition
1. cartilage model covered by perichondrium
2. a blood vessels enters the diaphysis midway penetrating the perichondrium
3. osteoprogenitor cells enlarge and become osteoblasts
4. perichondrium = periosteum at this point

5. along with blood vessel penetration, a collar is formed.
6. cells of the newly made primary ossification center become more active
7. cartilage cells grow and burst causing an extracellular alkaline ph.
8. ph change causes the placement of mineral salts and hardening occurs
9. hardening stops diffusion of nutrients to cells
10. these cells die

11. the marrow cavity enlarges (as soft bone lessens)
12. additional blood vessels occupy the area
13. osteoblasts (of the inner periosteum) deposit new bone on the inside while other bone on the outside is being resorbed on the inside

14. additional blood vessels reach the epiphyses and form the secondary ossification centers.
15. bone has completely replaced cartilage except at epiphyses
16. growth plate separates epiphyses and diaphysis
17. mitosis of the cartilage cells occurs and new bone forms on the diaphyseal side of the growth plates
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