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Side Effects and Antidotes
DIT
31
Biology
Professional
03/26/2013

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Term
Anti-Cholinergic
Definition
Dry, Hot, Blind, Red, Mad, Constipated

Atropine, TCA, H1 blocker, Low-potency neuroleptics, Digoxin, Amantadine
Term
Coronary vasospasm
Definition
Cocaine, Amphetamines, Tryptan

- treat post-SAH with Nimodipine
Term
Cutaneous flushing
Definition
- Vancomycin
- Niacin
- Adenosine
- Dihydropyridine calcium channel blockers
Term
Dilated cardiomyopathy
Definition
Doxo/Daunorubicin
Term
Torsades de pointes
Definition
Push IV Mg2+

- 1a/III anti-arrythmics
- Macrolides
- Haloperidol
- Chloroquine
- PI
Term
Agranulocytosis
Definition
Clozapine, CBZ, Colchicine, Propylthiuracil, Methimazole, Dapsone
Term
Aplastic anemia
Definition
- Chloramphenicol
- Propylthiouracil
- Methimazole
- NSAIDs
- Benzene
Term
Thrombocytopenia
Definition
- Heparin
- H2 blockers
Term
Hemolysis in G6PD
Definition
- INH
- Primaquine
- Dapsone
- Sulfonamides
- Fava beans
- Napthalene
Term
Focal massive hepatic necrosis
Definition
- Halothane
- Acetaminophen
- Valproic acid
- Amanita phalloides
Term
Hot flashes
Definition
Clomiphene and Tamoxifen
Term
Hypothyroidism
Definition
- Amiodarone
- Lithium
- Sulfonamides
Term
Gout
Definition
- Loops
- Thiazides
- Niacin
- Cyclosporine
Term
Photosensitivity
Definition
- Sulfonamides
- Amiodarone
- Tetracyclines
Term
Stephen Johnson Syndrome
Definition
- Seizures drugs
- Penicillins
- Sulfonamides
- Allopurinol
Term
Drug-induced lupus
Definition
SHIPP

1) Sulfonamides
2) Hydralazine
3) INH
4) Procainamide
5) Phenytoin
Term
Fanconi syndrome
Definition
PCT defect
Term
Interstitial nephritis
Definition
- Methicillin
- NSAID
- Furosemide
Term
Cinchonism
Definition
Headache and Tinnitus/Dizziness

1) Quinidine
2) Quinine
Term
Disulfiram-like
Definition
Metronidazole and Cephalosporins
Term
Nephro and Neurotoxicity
Definition
- AG
- Cysplatin
- Polymixin
Term
Nephro and Ototoxicity
Definition
- Vancomycin
- AG
- Cysplatin
- Furosemide
Term
Antidote for Salycilates
Definition
Acidic drugs need NaHCO3 or dialysis
Term
Antidote for Phenobarbital
Definition
Acidic drugs need NaHCO3-
Term
Antidote for Amphetamines
Definition
Basic drugs need NH4Cl
Term
Antidote for Beta blocker overdose
Definition
Glucagon

Remember, you GIVE a beta blocker for Theophylline overdose
Term
Antidote for Iron
Definition
DeFeroxime
Term
Antidote for Mercury, Arsenic and Gold
Definition
Dimercaprol and Succimer
Term
Antidote for Copper, arsenic and gold
Definition
Penicillamine
Term
Antidote for tPA, streptokinase, ect.
Definition
Aminocaproic acid
Term
Antidote for Theophylline overdose
Definition
Beta blocker
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