Shared Flashcard Set

Details

SGAs
Second Generation Antipsychotics
9
Pharmacology
Professional
11/13/2010

Additional Pharmacology Flashcards

 


 

Cards

Term

Risperidone

Definition
  • Risperdal
  • Starting dose: 1-2
  • Dose range: 2-6
  • Max dose: 16 
  • Note: risk of EPS > 6mg
  • Metabolism: 2D6 (major); 3A4 (minor)  
Term

Paliperidone

Definition
  • Invega
  • Starting dose: 6
  • Dose range: 6-12
  • Max dose: 12
  • Note: Food ↑ bioavailability by 60%
  • Metabolism: 2D6 (major); 3A4 (minor)

 

Term

Olanzapine

Definition
  • Zyprexa
  • Starting dose: 2.5-10
  • Dose range: 5-20
  • Max dose: 20
  • Metabolism: 1A2 (major); 2D6 (minor)

 

Term

Ziprasidone

Definition
  • Geodon
  • Starting dose: 20 bid with food
  • Dose range; 120-160
  • Max dose: 160
  • Note:↑ q 2 days, 500 cal food required
  • Metabolism: 2/3 aldehyde oxidase; 1/3 3A4
Term

Quetiapine

Definition
  • Seroquel
  • Starting dose: 25mg bid
  • Dose range: 300-800
  • Max dose: 800
  • Note: 2-3 divided doses with light meal or snack
  • Metabolism: 3A4 (major); 2D6 (minor)
Term

Aripiprazole

Definition
  • Abilify
  • Starting dose: 10-15
  • Dose range: 10-15
  • Max dose: 30
  • Note: ↑ q 2 week
  • Metabolism: 2D6 (major); 3A4 (major)
Term

Clozapine

Definition
  • Clozaril
  • Starting dose: 12.5-25
  • Dose range: 300-450
  • Max dose: 900
  • Note:↑ q25-50mg/d; qd or bid
  • Metabolism: 1A2 (major); 2D6,3A4,2C19 & others (minor) 
Term

Asenapine

Definition
  • Saphris
  • Starting dose: 5 bid subling
  • Dose range: 5 bid
  • Max dose: 5 bid
  • Notes: Do NOT swallow, no eating & drinking for 10 min
  • Metabolism: 1A2 (major); 3A4 (minor)
Term

Iloperidone

Definition
  • Fanapt
  • Starting dose: 1 bid
  • Dose range: 12-24
  • Max dose: 24
  • Notes:↑2mg/day due to orthostatic hypotension
  • Metabolism: 2D6; 3A4
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