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SFOS
Cardio
42
Biology
Graduate
04/09/2009

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Term
mean arterial pressure
Definition
(closer to diastole-lower pressure)
Area under the pressure curve
(Diastolic pressure+pulse pressure)/3
Term
pulse pressure
Definition
systolic pressuer-diastolic pressure
Term
Series resistance
Definition
found in kidneys and GI.
Total resistance is sum of individual resistances
Term
parallel resistance
Definition
most of cardio system
different flow across each resistance element
Pressure drop across each equal
resistance elements the sum as reciprocals
Term
vasomotion
Definition
precapillary smooth muscle, cyclical to create waves of blood flow to tissue
Flow longer when metabolic needs are hight
Term
continuous capillaries
Definition
characterized by endothelium in close contact.
transfer occurs by diffusion,
heart, skeletal muscle, skin, brain barriers
Term
capillary physical pressure (hydrostatic)
Definition
PHYSICAL force tending to push fluid OUT of the capillary
Term
interstitial fluid hydrostatic pressure
Definition
PHYSICAL force tending to push fluid back INTO a capillary
Term
plasma colloid osmotic pressure
Definition
OSMOTIC force which tends to draw fluid back INTO the capillary
Term
interstitial fluid colloid osmotic pressure
Definition
OSMOTIC force acting to pull fluid OUT of the capillary
Term
Forces which favor fluid LOSS out of capillary
Definition
capillary hydrostatic pressure (Pc)
interstitial fluid osmotic pressure
Term
Forces which favor reabsorbtion back INTO capillary
Definition
interstitial fluid hydrostatic pressure (Pif)
capillary osmotic pressure
Term
Factors that contribute to edema
Definition
increases capillary permeability (fluid OUT)
decreased plasma colloid osmotic pressure (draws LESS fluid IN)
elevated capillary pressure (dilate arteries)
lmyphatic obstruction
Term
Basal Tone
Definition
Local control element
Arteries have intrinsic property to maintain present vascular tone INDEPENDENT of neural activity
Term
Autoregulation of Blood Flow
Definition
The ability of an organ to maintain constant blood flow despite large changes in perfusion pressure
(assuming metabolic needs are constant and there is NO neural influence)
Heart, kidneys, brain
Term
Reactive Hyperemia
Definition
Blood flow increases after a period of blood flow restriction to make up for lost oxygen. Controlled at the level of the arterioles (independent of neural input)
Term
Active (functional) Hyperemia
Definition
increase in blood flow in response to an increase in metabolic activity
Blood pressure constant
Increase in demand leads to an increase in flow
Term
interdependence with atelectasis
Definition
when the lung collapses the blood vessels do too.
Term
P wave
Definition
atrial muscle depolarization
Term
QRS
Definition
Large deflection representing when the Purkinje fibers begin to activate the ventricular myocardium
Term
PR interval
Definition
represents the depolarization of cells from the SA node to the AV node. Important measure of conduction
Term
T wave
Definition
generated when the ventricles repolarize
Term
ST segment
Definition
brief isoelectric period when all regions of the myocardium are in plateau
Term
isovolumetric contraction
Definition
time it takes for ventricular pressure to exceed that in the great arteries. when ventricles are not emptying
Term
EDV
Definition
ventricular volume at the end of filling
Term
ESV
Definition
ventricle volume at the end of systole (contraction)
Term
stroke volume
Definition
volume of blood pumped into the aorta during one cardiac cycle
calculated as difference between EDV and ESV
Term
S1
Definition
first heart sound
The closing of the AV valves at the onset of ventricular systole (contraction)
Term
S2
Definition
second heart sound
Closure of the aortic pulmonary valves
Term
S3
Definition
vibration of the blood filling the ventricle during diastole (relaxation)
ventricular filling
Term
S4
Definition
Atrial kick sound at the end of diastole
atrial contraction sound
Term
compliance
Definition
ability of the veins to store blood.
C=change in volume/change in pressure
veins hold 60-80% of blood
Term
Atrial fibrillation
Definition
absence of P waves on ECG
Term
v wave
Definition
opening of mitral valve
Term
isovolumetric contraction
Definition
Period of time it takes for the ventricular pressure to exceed that in the great arteries. ventricles are not emptying.
causes semilunar valves to open
Term
factors that increase with increasing preload
Definition
Cardiac output, stroke volume, contractile function,
Term
Poiseuille's Assumptions
Definition

flow is laminar

flowis through smooth cylindrical rigid tubes

flow is steady and constant

viscosity is constant

Term
Wolff-Parkinson White syndrome
Definition
congenital abnormality in which heart muscle makes an additional electrical connection between the atrium and ventricle. The ventricle may be excited prematurely changing the QRS pattern.
Term
decremental conduction
Definition
occurs when AV node is too quickly re-stimulated. leads to less calcium influx, smaller AP, slow conduction
Term
reentry
Definition
caused by impaired conduction
Term
bundle branch block
Definition
block in the bundles conducting cardiac impulses.
impulse goes through alternative pathway for ventricular depolarization
ventricular depolarization slow (WIDE QRS)
Term
atrial flutter
Definition
supraventricular tachycardia.
impulses take an abnormal path through atria
results in rapid, sometimes irregular heart rate
may cause blood to be pumped inefficiently
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