Details Title: Sexually Transmitted Infection Description: STDs Total Flash Cards: 48 Created: 04/26/2009 21:09:11		New Users: To study from this flashcard set, or to create your own your own study flash cards, REGISTER HERE. Existing Users: CLICK HERE. Additional Women's & Gender Studies Flashcards
Cards in this set: Term Syphilis Transmission Definition direct contact with spirochete can spread to any surface of body after contact Development of immunity cannot prevent reinfection Term Syphilis Primary Stage Definition Chancre PAINLESS Term Syphilis Secondary Stage Definition Disseminated infection Rash (hands and feet) lymphadenopathy condylomata lata Term Syphilis Latent Definition asymptomatic on gonig organ damage occurs CAN STILL BE TRANSMITTED Term Syphilis Tertiary Definition neurosyphilis CV gummas (granulomatous inflammation) Term Syphilis Diag Definition Rapid Plasma Test (RPR) Veneral Disease Research Lab (VDRL) Very sensitive Can be neg. early in infection False + 1%, more common during pregnancy Term Syphilis Diag Confirmation Definition Treponemal specific test (FTA-ABS) (TP-PA) Darkfield micro (not as common anymore b.c syphilis not as popular) highly specific Term Syphilis Treatment Definition Pen G Repeat serology at 6 adn 12 mo. Azithromycin in pen G allergic patients Term Syphilis Treatment latent and during pregnancy Definition Pen G in pregnancy use even if mother is allergic Term Herpesviridae Characteristics Definition double stranded linear DNA assemble of nucleocapsid in cell nucleus latent infection destroys cell Term Herpesviridae Transmission HSV1 HSV2 Definition Direct most asymptomatic viral DNA poly syn. Term Herpesviridae Epi of HSV1 Definition most of pop has prevalence related to age rising cause of genital herpes Term Herpesviridae Epi of HSV2 Definition 17% of pop most asymptomatic Term Herpesviridae Clinical Initial & Recurrent Definition Initial no antibodies in primary non primary, prior exposure to heterologous virus recurrent; prior exposure to homologous virus Term Herpesviridae Pathology Definition mucocutaneous infection ganglia (dorsal root) asymptomatic shedding Term Herpesviridae Presentation Definition Prodrome: itching, burning, tingling Lesions: vesicles which rupture. PAINFUL ulcers lesions can look like anything Term Herpesviridae Diag. (2 main) Definition viral culture - gold standard; neg. results do not rule out, sensitivity limited due to shedding time Serology - anti. to gG1 and gG2 Term Herpesviridae Treatment to initial episode Definition HSV2 - can have symptoms and not know have HSV2 treatment reduces duration and severity Term Herpesviridae Treatment to recurrent episode (Episodic) Definition 1. Treat at first sign of symptoms 2. Treat all the time to minimize risk of lesion Term Herpesviridae Vertical transmission Definition 50% symptomatic on first episode b.c no antibodies Term Herpesviridae Neonatal Definition majority at delievery post natal transmission can occur Term Human Papillomavirus Characteristics/Epi Definition 30% in US double stranded DNA worldwide cancer: types 16, 18 warts, types 6, 11 Term Human Papillomavirus Diag. Definition warts - appearance cervical dysplasia - abnormal cytology PCR Term Human Papillomavirus Treatment Definition remove warts virus NOT eradicated cryotherapy Trichloroacetic acid (TCA) (BCA) surgical removal Term Human Papillomavirus Vaccination Definition Quadravalent vaccine 11-12 yo Term Molluscum Definition DNA Pox salmon colored central umbilication Term Chlamydia Epi Definition MOST common reported infectous disease intracellular more common in women Term Chlamydia Trachomatis Definition bligate intracellular parasite elementary bodies; infectious reticular bodies; in host distinguished from other clam by inclusions containing glycogen Term Chlamydia Diag. Definition Tissue: standard, 60-90 sensitive, don't use swabs with wood sticks Direct immunoflorescence EIA: 85 sensi. Nucleic amplification assays (NAATs): test of choice PCR/LCR 95 sensi. Term Chlamydia Clinical LGV (Ulcer) Definition uncommon systemic, rare in US HIV more common Term Chlamydia Clinical Urogenital Tract Infection (3) Definition 1. urethritis - discharge, dysureia 2. mycopurulent cervicitis - purulent or mucopurulent endocervical exudate visible in endocervical canal, AND sustained encocervical bleeding easily induced 3. PID - upper female genital tract; affects pregnancies Term Chlamydia Clinical Men v Women Definition Men are symptomatic early Women asymptomatic until complication arises (PID) Term Chlamydia Clinical During Pregnancy Definition preterm delivery postpartum infection conjunctivitis! 6070% of newborns infected Term Chlamydia Treatment Urethritis/Cervicitis LGV PID Definition Urethritis/Cervicitis - Azithro or Doxy LGV - Doxy PID - broad spec. anti. Term Gonorrhea Characteristics Definition gram neg.; nonmotile; diplococci coffee bean shaped ox. positive only utilize glucose easily alter antigen structure Term Gonorrhea Epi Definition 2nd most common reported infection disease in US Term Gonorrhea path Definition infects mucosal surfaces; columnar or cuboidal epi. infects cervix and not vag. Term Gonorrhea Diag. (4) Definition endocervical specimen Gram Stain: very sensitive in men, less in women (DO NOT USE); leukocytes Culture: test of choice, dacron or rayon swab, modified Thayer Martin media, limited sensitivity NA Probe: high sens and specicifity NAATs: test of choice PCR/LCR Term Gonorrhea Clinical Definition similar to clymidea men symptomatic, women asympt. until PID, etc urethritis mucopurulent cervicitis PID Term Gonorrhea During Pregnancy Definition complication more common in women with infection septic spontaneous abortion preterm neonatal ophthalamia neonatorum Term Gonorrhea Treatment Definition Cefixime or Ceftraiaxone FLUOROQUINIOLONES no LONGER RECOMMENDED Cephalosporin in pregnant women 10-30% have chlamydia, TREAT FOR BOTH Term Gonorrhea Disseminated Infection Definition bacterimia petechial or pustular skin lesion, arthralgias pregnant women: fatal endocarditis Term Trichomonas Vaginalis Characteristics Definition direct genital contact 5-10% in men and women frothy discharge Term Trichomonas Vaginalis Diag. Definition Wet prep, moves around slide. Term Trichomonas Vaginalis Treatment Definition metronidazole treat partners Term Chlymidia, gonherria, syphilis, Herpes (HSV1 & HSV2), PID Definition Ryan's Mom Term Bacterial Vaginosis Skipped in lecture from 08 Characteristics Definition Most prevalent casue of vaginal discahge 50% women asymptomatic treatment of males do not benefit prevention Term Today, I received my passport in the mail. They got my birthdate wrong. Then I picked up my birth certificate that I had sent in with the application. Turns out my parents have been celebrating my birthday on the wrong day for 16 years. Definition FML