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Session Prep Questions
KYCOM COMLEX
637
Medical
Graduate
06/27/2014

Additional Medical Flashcards

 


 

Cards

Term
which mediators of inflammation are most likely to cause fever
Definition
IL-1, PGE, TNF
Term
what cell produces IL-1
Definition
macrophages
Term
what are 2 major cytokines best for antiviral
Definition
INFa and INFb
Term
what two complements are anaphylaxatoxins
Definition
C3a and C5a
Term
what disease has TSH receptor autoantibodies
Definition
graves
Term
what hypersensitivity causes arthritis, vasculitis, and glomerulonephritis
Definition
3
Term
oncogene that causes burkitt lymphoma
Definition
c-MYC
Term
2 tumor markers for prostate cancer
Definition
PSA
acid phosphatase
Term
what symbol is female in pedigree
Definition
circle
Term
on pedigree what does a heterozygote of autosomal recessive look like
Definition
half shaded
Term
inheritance of cystic fibrosis
Definition
autosomal recessive
Term
inheritance of glucose-6-phosphate DH deficiency
Definition
x-linked recessive
Term
inheritance of huntington disease
Definition
autosomal dominant
Term
chromosomal deletion of cri du chat
Definition
5p
Term
HLA type of ankylosing spondylitis
Definition
HLA-B27
Term
most common cancer in men and women
Definition
men: prostate
women: breast
Term
what is the name of the type of cell one looks for in a test for SLE that involves patient macrophages being mixed with injured leukocytes
Definition
LE cell
Term
5 features of CREST
Definition
calcinosis
raynauds
esophageal dismotility
scleroderma
telangestica
Term
what immune deficiency has tetany and fungal/viral infections
Definition
digeorge: decreased parathyroid leads to decreased Ca and tetany. decreased thymus leads to decreased immune system
Term
what do alcohol and barbituates do to p450
Definition
induce causing more breakdown of drugs
Term
to minimize hearing damage aminoglycosides should never be combined with
Definition
loop diuretics
Term
procanamide and hydralazine share common side effect
Definition
lupus like in slow acetylators
Term
antidote for opipod overdose
Definition
nalaxone
Term
when moving a vertebral segment away from neutral, which is passed first: physiologic or anatomic barrier
Definition
physiologic
Term
if a patient presents with cool dry ropy right paraspinal area is this a chronic or acute problem
Definition
chronic
Term
if a lumbar vertebraw is neutral and sidebent right which way is it rotated
Definition
left
Term
what direction to the superior facets face
Definition
BUM BUL BUM
cervical: back, up, medial
thracic: back, up, lateral
lumbar: back, up, medial
Term
sidebending occurs in what plane and axis
Definition
cronal plane
AP axis
Term
if a patient complains of upper arm, which anatomic site to you evaluate and treat first
Definition
thoracic vertebrae
Term
is myofascial release direct or indirect
Definition
both
Term
what clotting factors are affected by vitamin K
Definition
II, IV, IX, X
Term
3 things that trigger sickling in sickle cell anemia
Definition
low oxygen
dehydration
acidosis
Term
what pneumonia results in cold antibodies
Definition
mycoplasma (anti-RBC Ab cause hemolysis)
Term
what deficiency causes megaloblastic anemia and neurologial symptoms
Definition
B12
Term
what type of cell ruses in number after severe hemorrhage
Definition
reticulocytes
Term
if a patient were infected with parasites what WBC would you expect to see increased in number
Definition
eosinophils
Term
what leukemia is associated with the philadelphia chromosome
Definition
CML
Term
what cell type is classic in hodgkins disease
Definition
reed sternburg
Term
what disorder has osteolytic lesions of the skull and pelvis and bence jones proteins in the urine
Definition
multiple myeloma
Term
3 features of virchows triad
Definition
blood stasis
hypercoaguability
endothelial damage
(phlebothrombus risk factors/venous clots)
Term
what arteritis must be diagnosed early to prevent blindness
Definition
giant cell temporal arteritis
Term
what aneurysm is associated with polycystic kidney disease
Definition
berry
Term
what congenital heart abnormality is characterized by continous machine like murmur
Definition
PDA
Term
what is eisenmenger syndrome
Definition
reverse of a left to right shunt to a right to left shunt leading to pulmonary HTN
Term
in ischemic heart disease what two conditions can ST elevation represent
Definition
Q wave MI
prinzmetal vasospasm
Term
4 major complications of a MI
Definition
cardiogenic shock
muscle rupture
heart failure
arrhythmia
Term
are dyspnea and orthopenia a sign of left or right sided heart failure
Definition
left
Term
what endocarditis are those with previously damaged or abnormal heart valves are more risk of getting, what is the organism responsible
Definition
subacute - strep viridans (strep of mouth, often mutans), E. coli, gram negatives
Term
what syndrome involving the pericardium may occur following a MI
Definition
dresslers syndrome
Term
5 major jones criteria
Definition
rheumatic fever diagnosis

migratory polyarthritis
carditis
subcutaneous nodules
erythema migrinatum
syndehams chorea (st. vincent's dance)
Term
4 classifications of obstructive lung disease
Definition
chronic bronchitis
emphysema
asthma
broncholyitis
Term
what restrictive lung disease is caused by habitual inhalation of irritants like coal dust
Definition
pneumoconiosis
Term
DOC vaginal candidiasis and systemic candidiasis
Definition
vaginal: miconazole
systemic: fluconazole
Term
DOC for neisseria meningitidis
Definition
penicillin G
Term
DOC for neisseria gonorrhea
Definition
cephtriaxone
Term
3 anatomical aspects of cervical vertebrae (C2-7) that differ from spinal vertebrae
Definition
transverasarum foramen
bifid spines
uncovertebral joints of luska
Term
what ligament connects the dense to the foramen magnum
Definition
alar
Term
what scalenes elevate the first rib
Definition
anterior and medial
Term
if you are able to induce left translation what type of sidebending are you inducing
Definition
right
Term
if the occiput is rotated right what direction is it sidebent
Definition
left
Term
you are about to perform OMT on cervical spine what area must you start
Definition
thoracic spine then start with OA
Term
antidote of acetminophen overdose
Definition
N-acetylcystine
Term
what anti-TB drug is hepatotoxic
Definition
isoniazid
Term
what drugs are P450 inducers
Definition
"one pharmacetuical brings about rapid liver metabolism"
oral contraceptives
pnenytoin
barbituates
ethanol
rifampin
levodopa
methadone
Term
2 major causes of lobar pnaumonia
Definition
strep pneumo
klebsiella
Term
4 types of lung carcinoma
Definition
small cell
squamous cell
large cell
adenocarcinoma
Term
hematuria and RBC casts are usually indicative what what general classification of glomerulonephritis
Definition
nephritic
Term
most common nephrotic syndrome in children
Definition
minimal change disease
Term
three components of staghorn renal calculus, what is the cause
Definition
infection
Magnesium, phosphate, ammonia
Term
cause and DOC of syphillis
Definition
treponma pallidum
penicillin G
Term
what testicular germ cell tumor has high AFP, what ovarian tumor is the counterpart
Definition
yolk sac tumor
endodermal sinus tumor
Term
what ovarian tumor has cysts lined with epithelium
Definition
serous
Term
5 major risk factors for endometrial carcinoma
Definition
obesity
age >40
late menopause
early menarche
nullparity
Term
5 major risk factors for breast cancer
Definition
obesity
age >40
early menarche
late menopause
nullparity
Term
koplik spots in mouth indicate what disease
Definition
measles
Term
what esophageal diverticulum involves all layers of esophagus, which is only mucosal
Definition
all: true
mucosa: false/pulsion
Term
what do cloxacillin, oxacillin, and methacillin have in common with respect their their ability to kill pathogens
Definition
b lactaminase resistant
kill strep and staph
Term
what generation of cephalsporins are cefmandole and cefoxitin in
Definition
2nd
Term
what type of gastritis does H. pylori cause, why must it be treated ASAP
Definition
chronic B type
can cause gastric carcinoma
Term
what is the risk of developing colon cancer in familial polyposis
Definition
100%
Term
if patient presents with lots of abdominal pain, little to no blood in stool, skip lesions of ileum what is the cause
Definition
chrons disease
Term
3 components of charcots triad, what abdominal disease does it represent
Definition
RUQ pain, jaundice, fever
acute cholangitis
Term
where is the cause of jaundice if there is high serum unconjugated bilirubin, high serum conjugated bilirubin, and high serum both
Definition
unconjugated: prehepatic
conjugated: post hepatic
both: hepatic
Term
how are hepatitis A and B transmitted and their incubation times
Definition
A: fecal oral (2-6wk)
B: blood, sex, pregnancy (2-6mo)
Term
if a patient is positive for anti-HBsAg what disease do they have
Definition
vaccinated for hepatitis B, no disease
Term
patient presents with cirrhosis, new onset diabetes, bronze skin, what is the disease
Definition
hemochromatosis
Term
compare the finger abnormalities in RA and OA
Definition
RA: PIP and MCP predominate
OA: DIP and heperdines nodules
Term
rule of three for thoracic vertebrae
Definition
T1-3 spine is at the same level
T4-6 spine is 1/2 below
T7-9 spine is 1 below
T10 spine is 1 below
T11 spine is 1/2 below
T12 spine is at same level
Term
what are the false ribs
Definition
8-10
Term
what is the primary motion of the thoracic spine
Definition
rotation
Term
what are the pump handle, bucket handle, and caliper ribs
Definition
pump: 1-5
bucket: 6-10
caliper: 11-12
Term
what are the attachments of the diaphragm
Definition
ribs 6-12
L1-3
xyphoid process
Term
in an inhalation dysfunction is the the key ribs
Definition
bottom
Term
prostaglandins and bradykinins share what common feature in terms of how we feel when we get sick
Definition
pain
vasodilation
Term
what cell makes IL-1, what does it do
Definition
macrophages make it
stimulates CD4 T cell
causes fever
Term
if there is no male to male transmission and the parents are not sick what is the inheritance
Definition
x-recessive
Term
what is the HLA type of MS and nacrolepsy
Definition
DR2
Term
what is the VRDL and FTA-ABS test result in a SLE patient, why
Definition
VDRL positive because it tests for anti-cardiolipin (anti-phospholipid Ab) which is on syphillis and also made when SLE destories cells and they body sees the mitochondria membrane

FTA-ABS negative
Term
what clotting pathway does PTT, PT, and bleeding time test
Definition
PTT: intrinsic
PT: extrinsic
bleeding time: platelet number
Term
what do the direct and indirect coombs tests evaluate
Definition
direct: anti-Rb antibodies (like in pregnancy)
indirect: anti-RBC antibodies (warm/cold hemolytic anemia)
Term
what macromolecule is reliant on folic acid and vitamin B12 for synthesis, how is this related to anemia
Definition
DNA
if you can't make DNA then cells stop dividing making large cells but less cells
Term
auer rods and myeloblasts are evidence of what disease
Definition
AML
Term
aminoglycosides are most effective against gram positives, gram negatives, or both
Definition
gram negatives
Term
what type of arterial inflammation is associated with hypersensitivity to tobacco
Definition
buerger's / thromboangiitis obliderans
Term
what disease do blue bloaters have, is it obstructive or restrictive
Definition
chronic bronchitis
obstructive
Term
what drugs are P450 inhibitors
Definition
"some pharmauticals can inhibit drug catabolism"
sulfonamides
pnehylbutazone
chloramphenicol
isonizid
dicumarol
cimetidine
Term
antidote for methanol
Definition
ethanol
Term
DOC strep pyogenes
Definition
pen G or V
benzathine
Term
DOC barrelia burdgorferi
Definition
doxacycline
Term
what plane and axis is flexion
Definition
plane: horizontal
axis: transverse
Term
what is the classic cell in hodgkins disease
Definition
reed sternburg
Term
what athlerosclerosis is due to high serum calcium
Definition
monckerbergs
Term
what athlerosclerosis is due to malignant HTN
Definition
hyperplastic arterialLOsclerosis
Term
what athlerosclerosis is due to old age
Definition
hayline artheioLOsclerosis
Term
what athlerosclerosis is due to high lipid diet
Definition
atherosclerosis
Term
a 3yo japanese boy presents with very red hands and soles of the feet, conjunctivitis, what does he have
Definition
kawaski arteritis
Term
if the atlas is sidebent left what is the rotation
Definition
right
Term
if C5 is more easily translated left in flexion and there is equal translation right and left when in neutral and not as equal bilateral translation in extension what is the dysfunction
Definition
C5 neutral
rotated right
sidebent right
Term
is serum calcium, phosphate, and alkaline phosphatase high, normal, or low in oestoperosis, osteomalacia, and pagets
Definition
osteoperosis: normal
osteomalacia: low Ca and P, high AP
pagets: high AP
Term
what is the most common type of cartiladge
Definition
hayline
Term
what bone cancer is agressive, usually in pelvis and long bone marrow cavities, and more in young males
Definition
eqings sarcoma
Term
why are the calves in duchenne muscular dystrophy large
Definition
infiltration with fat and CT
hypertrophy
Term
what is the most common supratentorial tumor in children
Definition
craniopharyngioma
Term
what CNS disorder has bradykinesia, resting tremor, rigidity
Definition
parkinsons
Term
if one is spastic with increased DTR is it a lower or upper motor neuron lesion
Definition
upper
Term
what is the age of onset for MS, what is the physiological change
Definition
20-40yo
demyelination
Term
what is the hormone produced in cushings syndrome
Definition
cortisol
Term
what adrenal products are in excess in Conn's disease, what is the effect on serum Na levels
Definition
ALD
increased Na
Term
contrast graves disease and plummers hyperthyroid size of follicle and colloid
Definition
graves: small follicle, low colloid
plummer: large follicle, high colloid
Term
are the PTH and Ca levels high or low in hypoparathyroid and pseudohypoparathyroid
Definition
hypoparathyroid: low PTH and Ca
pseydohypoparathyroid: high PTH and low Ca
Term
is DM1 or DM2 prone to ketoacidosis and obesity
Definition
DM1 ketoacidosis
DM2 obesity
Term
what are the 4 organs involved in MEN1
Definition
pituitary adenoma
pancreatic carcinoma
parathyroid
adrenal adenoma: pheochromocytoma
Term
what are the ABC's of melanoma
Definition
A: asymmetry
B: irregular borders
C: different colors
D: diameter >3mm
E: different elevations
Term
what skin disease is due to autoantibidoes against the intercellular junctions between keratinocytes
Definition
phemygus
Term
what are the two organs most affected by mercury poisoning
Definition
CNS
kidney
Term
what guanine analog is DOC for herpes simplex
Definition
acyclovir
Term
what color are gram positive bacteria after gram staining
Definition
blue violet
Term
what kind of colitis has a risk after use of broad spectrum antibiotics, what is the causative agent
Definition
clostridium difficile, pseudomembranous

clindamycin
Term
what organ is destoried in acetminophen overdose
Definition
liver
Term
of what are most renal calculi comprised
Definition
calcium
Term
what type of aneurysm are marfans patients most predisposed towards
Definition
dissecting aortic
Term
what germ cell tumor is associated with painlss enlargement of the testies and is often curavle because of its radiosensitivity
Definition
seminoma
Term
what is the causative agent of condyloma acuminatum and conduloma lata
Definition
acuminatum: HSV
lata: syphillis
Term
what is the source of a-amanitin
Definition
poison mushrooms
Term
if a patient is + HBsAg what is their diagnosis
Definition
current Hep B infection
Term
if a patient has rectal pain, bright red blood in stool, pseudopolyps on colonoscopy, what is the disease
Definition
ulcerative colitis
Term
what kind of tumors other than colon carcinoma are associated with turcots disease
Definition
malignant brain tumors
Term
what are the 4 subtypes of hodgkins and what type of reed sternburg to they have
Definition
lymphocyte predominate: less RS cells (better prognosis) lymphostocystic RS B markers

nodular sclerosis: lacunar RS, 50/50 RS cells, moderate prognosis

mixed cellularity: classic RS with CD15

lymphocyte depletion class RS, high amounts of RS bad prognosis
Term
inheritance of achondroplasia
Definition
AD
Term
compare and contrast gilbert and crigler najjar
Definition
gilbert: decreased uridine diphosphoglucronlgransferase, mild impairment in uptake, evident in times of stress

crigler: severe impairment of uptake, chronic
Term
what cells of CD3a and CD5a stimulate
Definition
mast cells
platelets
basophils
Term
what type of fungal infection is amphotericin used
Definition
disseminated coccidiomycosis
rhizopus
fusarium
alternate for aspergillus, cryptococcal meningitis
Term
DOC amebiasis
Definition
metronidazole
Term
DOC CMV
Definition
gancyclovir
Term
DOC pneumocystis carnii
Definition
TMP/SMX
Term
cryptococcus neoformans
Definition
fluconazole
Term
what type of bacterial has no cell wall
Definition
mycoplasma
Term
what is the effect of botulinum toxin on neurons and clinically
Definition
blocks ACh receptors at NMJ
1. constipation
2. flaccid paralysis decending
3. respiratory paralysis
Term
what are the O2 requirements for mycobacterium TB
Definition
obligate aerobe
Term
2 most common causes of otitis media
Definition
strep pneumo
H. influenzae
Term
most common cause of pneumonia in young adults
Definition
mycoplasma
Term
3 most common causes of meningitis in neonates
Definition
1. GBS
2. E. coli
3. listeria
Term
most common cause of bacterial endocarditis
Definition
s. viridans (mouth)
Term
only species of group A B-hemolytic strep
Definition
strep pyogenes
Term
S. viridans: hemolytic nature, bile solubility, optochin sensitivity
Definition
alpha hemolytic
bile insoluble
optochin resistant
Term
what organism is associated with waterhouse friderichsen syndrome
Definition
neisseria meningitidis
Term
what is the gram stain of E. coli
Definition
negative
Term
what two bacteria are arranged in growth pattern like chinese characters
Definition
cornebacterium diptheria
listeria monocytogenes
Term
two major toxins made by clostridium perfringens and the disease caused by them
Definition
alpha toxin: gas gangrene
enterotoxin: food poisoning
Term
compare E. coli, salmonella, and shigella in terms of gram stain, motility, and lactose fermentation
Definition
E. coli: gram negative, motile, ferments

Salmonella: gram negative, motile, no ferment

shigella: gram negative, immotile, no ferment
Term
most common cause of UTI
Definition
E. coli
Term
what organism causes pneumonia with cirrent jelly sputum
Definition
klebsiella
Term
what comma shaped organism causes rice water stool
Definition
vibro cholera
Term
pasteurella is a common pathogen in wounds caused by? what 2 infections does it cause?
Definition
dog/cat bites
cellulitis
osteomyelitis
Term
what organism creates green blue exudate or pus, smells musty, and often infects burns
Definition
pseudomonas
Term
is most illness and morbidity of TB due to the primary or reactivation infection
Definition
reactivation
Term
what two bacterial genera where commonly confused with fungi due to the filamentous and branching growth? how are they different in terms of natural habitats and oxygen requirements
Definition
gram positive rods
actinomyces: infects contact lenses, water, soil mouth, sinuses
nocardia: acid fast, in soil and lungs
Term
what is the causative agent of lyme, what is the name of the buch and the lesion
Definition
borella burgdoferi
bulls eye rash, erythema chromcum migrans
Term
in what form is chalmydia infective
Definition
elementary body
Term
what is the most common agent of non-gonoccal urethritis
Definition
chalmydlia
Term
what are the 3 typhi, their cause, and their vector
Definition
epidemic: R. prowazekii, flying squrriel, human, lice

endemic: R. typhi - rats and fleas

scrub: R. tustugamushi - rodents and mites
Term
what demyelinating disease follows viral infection, affects PNS, mostly motor, ascending muscle weakness and paralysis
Definition
guillian barre
Term
what 5 structures must be present for it to be a typical rib
Definition
head
neck
tubercle
angle
shaft
Term
the spine of the scapula is at what vertebral level
Definition
T3
Term
route of transmission and incubation time for hepatitis C
Definition
sex, birth, blood
1-2 mo
Term
what is the composition of most kidney stones
Definition
calcium
Term
what two species of bacterial are associated with development of struvite
Definition
proteus morabalis
staph saphrophiticus
Term
what organs are affected by MEN 1
Definition
pituitary adenoma
adrenal pheochromocytoma
parathroid
pancreas carcinoma
Term
what organs are effected by MEN 2
Definition
adrenal medulla pheochromocytoma
thyroid medullary carcinoma
hyperparathyroid
Term
describe feet of friedreich's ataxia patients
Definition
pes cavus: cave in sole, high arches
Term
is ALS are disease of UMN, LMN, or both
Definition
both
Term
what two bones when fractures are notoriously prone to avascular necrosis
Definition
scaphoid
femoral head
Term
is there increased conjugated or unconjugated bilirubin in gilberts, crigler najjar, dubin johnson, rotor
Definition
gilbert: UC
crigler: UC
dubin: C
rotor: C
Term
what is the difference in terms of formation, components and dangers associated with complete vs incomplete hydatiform mole (used Rehymer explination thought it was better)
Definition
complete: fertilized empty egg with 2 sperm (46 chromosomes). COMPLETE mom absence. COMPLETE villi edematous/hydropic. trophoblasts COMPLETELY cover villi (more b-hCG). COMPLETE risk for choriocarcinoma

partial: fertilize 1 egg with 2 sperm. PARTIAL genetic material correct. PARTIAL fetal formation. PARTIAL circumference of trophoblasts around hydropic villi. villi PARTIALly have edema, some are normal. PARTIAL risk of choriocarcinoma
Term
20yo make, bloody stool for 1y, abd pain, symptomatic arthritis, iritis. top of DDX list for the bloody stool is
Definition
ulcerative colitis
Term
what is the causative agent of 5th disease, what are two other names
Definition
parvovirus B19
slapped cheek disease
erythema infectiousum
Term
compare chicken pox and small pox synchrony of evolution
Definition
chicken pox are in all different stages
small pox are all in the same stage
Term
what type of cosackie is associated with myocarditis and what type hand foot and mouth disease
Definition
B is myocarditis
A hand foot mouth
Term
what causes measles and german measles
Definition
measles is rubeola
german measles is rubella
Term
what type of disease does rotavirus cause, what family is the virus in
Definition
gastrenteritis in kids
reoviridae
Term
4 classes of antibiotics that inhibit translation in bacteria
Definition
aminoglycosides
macrolides
tetracyclines
chloramphenicol
clindamycin
Term
what do methotrexate, trimethoprim, and pyrimethamine have in common
Definition
all inhibit folate
Term
what is the MOA of rifampin, what disease does it treat
Definition
transcription inhibitor
TB
Term
what level does the spinal cord end in most people
Definition
L1-2
Term
why is the lumbar spine more susceptible to herniation
Definition
the posterior ligament is thinner
Term
what is the primary flexor of the hip
Definition
iliacus
Term
how does a small fergusons angle affect the curvature of the spine
Definition
small means they have a flat back with little lordosis
Term
if a patient has a herniated L3 disc what root is affected
Definition
L4
Term
what are the major types of spina bifida and what does each represent
Definition
occulta: laminae malformation, hair or nevi

meningocele: meningies malformation

meinogomyeloele: meninges malformation and herniation of nerve roots

rachischisis: full or open to CNS
Term
what is the term for anterior displacement of the vertebrae with respect to the one inferior
Definition
spondilolisthesis
Term
what dermatone is the umbilicus
Definition
T10
Term
what is the vector for hanta virus, what infection does it cause
Definition
deer mice urine, feces, saliva
respiratory infection
Term
what is the causative agent of subacute sclerosing panencephalitis
Definition
measles
Term
7 prion diseases
Definition
kuru
CJV
CJV varient
bovine encephalitis
scarpie
fatal familial insomnia
gerstmann straussler scheinker
Term
what is the term for a virus that integrates itself into the host genome
Definition
provirus
Term
what HIV glycoprotein mediates HIV binding to the CD4 receptor, which mediates HIV fusion to the cell
Definition
CD4: gp120
fusion: gp41
Term
is cryptococcus a yeast or mold
Definition
yeast
Term
if a tissue specimen of infected area reveals cigar shaped budding yeast what is the cause
Definition
sporotrichosis
Term
if a slide made from a vaginal swab is examined and germ tubes and pseudohyphae are found what is the infection
Definition
candidia
Term
stages of plasmodia development
Definition
1. sporozoite injected
2. in liver 30min
3. developed into merozoites
4. enter RBC
5. A. make more merozites which lyse RBC every 48h (72h for malariae)
5. B. gametocyte released and sucked into mosquito and turns into sporozoite
Term
what species of plasmodium is the most severe and life threatening
Definition
falciprum
Term
what is the causative agent of kala-azar, what is another name for this disease
Definition
leshmania donovani
black sickness
Term
what is the vector and cause of chagas disease
Definition
T. crusi
kissing/reduvidd bug
Term
DOC for entamoeba histolytica
Definition
metranidazole
Term
DOC giardia lambila
Definition
tindazole
Term
DOC trachomonas
Definition
metronidazole
Term
compare location of schistoma mansoni, japonicum, hematobium
Definition
mansoni: colon
japonicum: SI and liver
hematobium: bladder
Term
what is the generic term for cestode
Definition
tapeworm
Term
what nematode causes perianal puritis especially at night
Definition
pinworm
enterobius vermicularis
Term
if the Km of an enzyme is high what is the affinity of the substrate
Definition
low
Term
by what two amino acids does trypsin cleave, does it cleavy carboxy or amino side
Definition
lysine and argining
carboxy
Term
what AA is the source of GABA
Definition
glutamate
Term
what is the molecular type (macromolecule) of all exotoxins
Definition
polypeptides proteinaceous
Term
what PAS character do mucosal macrophages in whipples disease have
Definition
positive
Term
why is takayasu disease called pulseless disease
Definition
granulomas on aorta decrease recoil and decrease pulse
Term
which are motile: E. coli, salmonella, shigella
Definition
E. coli
salmonella
Term
what antibody type crosses the placenta
Definition
IgG
Term
what is the MOA for killing of plasmodium by chloroquine
Definition
makes heme toxic
lyses RBC
inhibits DNA
alkalizes food vacoule
Term
MOA primaquine
Definition
kills liver hyponozites
kills gametocytes to decrease spread
Term
what type of staph is associated with UTI
Definition
saphrophiticus
Term
what stain is used for cryptococcus
Definition
india ink
Term
what enzyme does methotrexate inhibit, what effect does this have, what product is no longer made
Definition
inhibits folate which stops dihydrofolate reductase so you cannot turn dihydrofolate into tetrahydrofolate and thus cannot make nucleotides
Term
DOC leshmaniasis
Definition
stilboglucinate
Term
common contaminating agent of bodies of water with leptospira interrogans
Definition
rat, mouse, cat, dog urine
Term
what HLA is associated with psoriatic arthritis, what other disease are associated with this HLA
Definition
B27
ankylosing spondylitis
reactive arthritis
Term
what is the number one cause for amenorrhea
Definition
pregnancy
Term
is prader willi due to maternal or paternal deletion of 15q11-13
Definition
paternal
Term
explain the pentose phosphate shunt
Definition
glucose + Mg + Ca > NADPH + H

NADPH + H + FAD + glutathione reductase > glutathione

glutathione + H20 + glutathione peroxidase > 2 H20
Term
most common side effects of cisplatnin
Definition
peripherial neuropathy
ototoxicity
nephrotoxicity
severe vomiting
Term
most common side effects of cyclophosphamide
Definition
hemorrhagic cystitis and fibrosis
Term
most common side effects of bleomycin
Definition
pulmonary fibrosis
extravasion
Term
what enzyme is missing in phenylketonuria
Definition
pnenylalanine hydroxylase
Term
triad for pellagra
Definition
dermatitis
diarrhea
dementia
Term
stops from phenylalanine to the production of epinepherine
Definition
pnenylalanine + phenylalanine hydroxylase > tyrosine

tyrosine + tyrosinase > dopa

dopa > dopamine > NE

NE + vitamin C and Ca > epi
Term
what amino acids build up in maple suryp urine disease
Definition
isoleucine leucine valine
Term
what kind of sugar is glucose based on the number of sugars it has
Definition
hexose
Term
hexokinase vs glucokinase: location and affinity for glucose
Definition
hexokinase: most tissues, low affinity

glucokinase: liver, B islet cells, high affinity
Term
what types of glycocidic bonds exist between sugars of sucrose, glycogen and cellulose
Definition
sucrose a1,2
glycogen a1,4, a1,6
cellulose B1,4
Term
lactose intolerance is due to a defect in what enzyme
Definition
lactase
Term
main clinical effects of fructosuria vs fructose intolerance
Definition
fructosuria: benign, fructose in urine

fructose intolerance: fructose builds in kidney and liver causing failure and hypoglycemia
Term
why does von girke not invade skeletal muscle
Definition
no gluconeogenesis in muscle
Term
what COX inhibitor has no anti-inflammatory activity
Definition
acetminopehn
Term
3 enzymes involved of breaking down glycogen into glucose
Definition
glucose-6-phosphatase
phosphorlyase
glucomutase
Term
what 2 mucopolysaccharidoses have defect in a=L iduronidase
Definition
hurler and scheie
Term
are these FA saturated or unsaturated: palmitic, linoleic, linolenic, oleic
Definition
palmitic: saturated
lnoleic: poly unsaturated
linoleic: poly unsaturated
oleic: mono unsaturated
Term
what is enterohepatic circulation
Definition
liver > bile > GB > bile ducts > sphinctor of oddi > duodenum > ileum > liver
Term
4 components of a triglyceride and glycerophospholipid
Definition
TG: glycerol + 3 FA

glycerophospholipid: glycerol + 2 FA + 1 phospholipid with specific head
Term
what type of lipid is lecithin
Definition
glycerophospholipid
Term
what type of lipid is cardiolipin
Definition
glycerophospholipid
Term
what sphingolipidosis is associated with blindness and a cherry red macula and is more common in jews
Definition
tay sacs
Term
what enzyme is defective in gauchers
Definition
B-glucosidase
Term
what is the mechanism of photosensitivty associated with prophyrias
Definition
sun turns prophinogen into porphoryn
oxygen causes porphoryn to release ROS
ROS causes photosensitivty reaction
Term
what steps of heme synthesis does lead inhibit
Definition
ALA dehydrogenase
ferrocheltilase
Term
what 2 metabolic processes does the liver use to maintain glucose levels
Definition
glycogenolysis
gluconeogenesis
Term
in normal non fasting person what is the only energy sources for the brain and for RBC, what about in starvation
Definition
non fasting: both use glucose

starvation: brain can use ketones, RBC need glucose
Term
what is the disorder caused by thiamine deficiency
Definition
beriberi
Term
what virus causes measles
Definition
rubeola
Term
which cosackie virus causes myocarditis
Definition
B
Term
DOC trichomonas
Definition
penicillin G
Term
DOC chalmydlia
Definition
doxycycline or ceftriadone
Term
DOC mycoplasma pneumonia
Definition
erythromycin
Term
DOC myconacteria leprae
Definition
rifampin and dapsone
Term
what ribosome subunit is acted on by aminoglycocides
Definition
30S
Term
what ribosome subunit is acted on by tetracyclines
Definition
30s
Term
what ribosome subunit is acted on by chlorphenicol
Definition
50S
Term
what ribosome subunit is acted on my macrolides
Definition
50S
Term
in what developmental stage are plasmodia when they are injected into human body
Definition
sporozoite
Term
what is the cause of infectious mononucleosis
Definition
EBV
Term
MOA of gold in RA
Definition
stops macrophage lysosome formation
builds up in joints best
Term
DOC acute attack of gout
Definition
first line is NSAID
DOC colchisine
Term
how many vertebrae is the sacrum
Definition
5
Term
3 accessory ligaments of the sacrum and their attachment
Definition
sacrotuberosus: sacrum, ischial tuberosiry

sacrospinous: sacrum, ischial spine

iliolumbar: iliac crest, L5-5
Term
what is the first ligament to become tender in a lumbosacral dysfunction
Definition
iliolumbar
Term
3 functions of the piriformis
Definition
external rotation
abduction
extension
Term
what nerve roots constribute to the lumbar plexus, sacral plexus, and sciatic nerve
Definition
lumbar: T12-L4
sacral: L2-S4
sciatic: L2-S3
Term
4 types of sacral motion, under what conditions, what horizontal axis
Definition
inherent (S2): craniosacral, superior axis
respiratory: horizontal
postural: transverse S3
dynamic: oblique
Term
if L5 is rotated left what direction is the sacrum rotated
Definition
right
Term
if L5 is sidebent left what side is an oblique axis of the sacrum engaged
Definition
left
Term
what enzyme in the glycolytic pathway is inhibited by ATP and citrate but activated by AMP and 2,6-diphosphate
Definition
phosphofructokinase 1
Term
what effect does phosphorlyation have on hormone sensitive lipase
Definition
activation
Term
what class of steroid are glycocholate, taurocholate, cortisol, DHEAS
Definition
glycholate: bile acids
cortisol: glucocorticoids: DHEAS androgen
Term
what layer of the adrenal cortex produces aldosterone, cortisol, and testosterone
Definition
zona glomerulosa: ALD
zona fasicularis: cortisol
zona reticularis: testosterone
Term
do the testies make glucocorticoids and ALD
Definition
no
Term
in male peripheral metabolism and two molecules is testosterone converted to
Definition
estrone and DHT
Term
what cells of the ovary have the same chlesterole dependent pathway as the same productions of that pathway as leydig cells of the testes
Definition
theca cells produce androgen
Term
in the granulosa cells of the ovary what two molecules is androstendione converted to
Definition
estrone and testosterone
Term
how does female peripheral metabolism differ from male peripheral metabolism with regard to cholesterol dependent products
Definition
male: DHT > androsteindione, estrone, testosterone

female; estrol > androstendione, estrone, testosterone
Term
does the corpus luteum make esteogrn
Definition
no
Term
in 17a-hydroxylase deficiency what hormones are deficient
Definition
sex steroids
ALD
Term
in 21a-hydroxylase deficiency what hormones are deficient
Definition
ALD and cortisol
Term
in 11b-hydroxylase deficiency what hormones are deficient
Definition
cortisol and ALD
Term
is fat lysis stimulated by insulin, glucogen, or growth hormone
Definition
glycogen and growth hormone
Term
what are the purines and pyrimidines
Definition
purines: adenosine, guanine
pyrimidines: uracil, thymidine, cytosine
Term
in lesch nyhan defective HGPT causes inability to salvage purines so they are degraded to this molecule which is the cause of the symptoms
Definition
uric acid
Term
the segment of bacterial DNA that consists of promoter, operator, and one or more structural genes is called
Definition
operon
Term
how many structural genes are associated with promoter in prolaryotic genome and eukaryotic genome
Definition
monocystrionic in eukaryotes

polycystronic in prokaryotes
Term
if one has a seated flexion test positive on the left and there is a sacral oblique axis on what side will it be
Definition
right
Term
what does the standing flexion test evaluate that the seated flexion does not
Definition
lower extremities
Term
if the right ASIS is inferior and the right PSIS is superior and there is a positive standing flexion test on the right what is the innominate dysfunction
Definition
right anterior
Term
if the right ASIS is super and the right PSIS is superior and there is a positive standing flexion on the right, what is the inomniate dysfunction
Definition
right superior sheer
Term
4 causes of superior pubic shear
Definition
tight rectus abdomnius
pregnancy/labor
trauma
posterior innominate
Term
if the right ASIS is more lateral and there is a positive standing flexion test on the right what is the likley innominate dysfunction
Definition
right out flare
Term
what sacral dysfunction is VERY common in post partum females
Definition
bilateral sacral flexion
Term
what is the most common sacral shear
Definition
unilateral flexion
Term
the pt has left on left, what type of sacral dysfunction is this
Definition
physiological, forward torsion
Term
if there is a sacral dysfunction what area should be evaluated and treated first
Definition
lumbar spine (L5)
Term
what is the class of drug for cantopril and enalapril
Definition
ACEI
Term
what changes occur in electrolytes, urea, and glucose with thiazides
Definition
decreased Na and K
increased Ca and uric acid
hypoglycemia
Term
what region of DNA encodes a single protein in prokaryotes
Definition
cistron
Term
what is the major DNA polymerae in prokaryotes, what are its functions
Definition
RNA polymerase III: proofread, exonuclease, catalyze DNA replication
Term
what type of polymerase makes the leading strand in eukaryotic DNA replication, what are its other functions
Definition
polymerase E: acts as helicase (UNABLE to proofread or do exonuclease)
Term
what are the 3 germ layers
Definition
ectoderm
endoderm
mesoderm
Term
the median and medial umbilical ligaments were what structure in the fetus
Definition
median: urachius
mediaL: umbiLicaL artery
Term
what branch of the branchial arch are the muscles of mastication and facial expression derived
Definition
1st mastication
2nd facial expression
Term
from what pharyngeal pouches are the thymus and inferior parathyroids derived
Definition
3rd
Term
where are the cervical cysts located, from what fetal structure do they derive
Definition
anterior lateral neck
remnent of pharyngeal cleft
Term
what duct evuntally develops into vas deferens and epididymis
Definition
wolffian
Term
what duct evuntally develops into fallopian tubes?
Definition
mullerian
Term
what structures pass through the foramen ovale
Definition
V3
accessory meningeal artery
Term
what structures pass through the foramen spongiosum
Definition
middle meningeal artery
Term
what structures pass through the superior orbital fissure
Definition
CN 3, 4, 6,
superior opthalmic vein
sympathetic nerves
Term
what is the innervation of the lateral rectus
Definition
CN 6
Term
what is the innervation of the superior oblique
Definition
CN 4
Term
what muscle is relaxed in horner syndrome, why
Definition
muellers muscle
disrupted sympathetic control
Term
what muscle is responsible for midrasis and miosis
Definition
sphinctor pupiale - miosis
dilator pupiale - mydriasis
Term
pt has injury to right 12th CN to what side will that patients tongue deviate when he attempts to protrude his tongue
Definition
right
Term
which pterygoid operates to open the mouth
Definition
lateral
Term
what laryngeal muscle is NOT innervated by the recurrent laryngeal, what is the innervation
Definition
crycopharyngeal - superior laryngeal
Term
what muscle is paralized in scapular winging, what nerve
Definition
serratus anterior
long thoracic nerve
Term
what nerve roots supply the musculocutaneous, axillary, radial, and ulnar nerve
Definition
MCT: C5-6
axillary: C7
radial: C7
ulnar: C8-T1
Term
what cutaneous loss is associated with unlar nerve, musculocutaneous nerve, and radial nerve damage
Definition
ulnar: fingers 4.5-5 and lateral hand
MCT: lateral forearm
radial: lateral posterior forearm and hand without tips
Term
what nerve risks injury with a fracture to the humerus
Definition
radial in radial groove
Term
what type of fracture is a fracture of the distal radius
Definition
collies: land on outstretched hand
Term
for the hip what is the primary abduction, adductor, internal rotator, external rotator
Definition
abd: gluteus medius
add: adductor magnus and minimus
external: gluteus maximus
internal: gluteus medius and minimus
Term
what type of glomerular disease has crescents
Definition
rapid proliferative glomerular nephritis
Term
what are the categories of RPGN
Definition
1) Ab- idiopathic, goodpastures

2) immune complex- idiopathic, SLE, henoch purpura, post strep

3) ANCA- idiopathic, wegeners, micropolyangitis, polyarteritis nodosa
Term
what type of glomerulonephritis is goodpastures disease
Definition
nephritis
anti-glomerular BM disease
rapid proliferative later
Term
if a pt presents with inhaled dysfunction of ribs 3, 4, 5 what rib should you treat first
Definition
5
Term
what is the main motion of the OA, AA, and upper cervicals
Definition
OA: F/E
AA: rotation
cervicals: rotation
Term
DOC CMV retinitis
Definition
gancyclovir
Term
DOC esophageal candidiasis
Definition
fluconazole
Term
what generation of cephalosporin is cefazolin, cefoxitin, and ceftriaxone
Definition
cefazolin 3
cefoxitin 2
ceftriaxone 3
Term
what is the antidote to warfarin OD
Definition
vitamin k
Term
what is the antidote to benzo OD
Definition
flumanazil
Term
what drug is used to eliminate tapeworms
Definition
niclosamide
Term
what drug is used to eliminate flukes
Definition
praziquantel
Term
What is the innervation of the hamstrings
Definition
sciatic nerve
Term
what is the innervation of the quadriceps
Definition
femoral nerve
Term
what are the muscles of the hamstrings
Definition
biceps femoris
semitendinosus
semimembranosis
Term
how is foot movement affected by a peroneal nerve injury
Definition
cannot dorsiflex
Term
contents of superior, middle, posterior, and anterior mediastinum
Definition
superior: thymus, aortic arch, esophagus, trachea

anterior: nothing

middle: heart

posterior: esophagus
Term
at what point in the cycle of heart contraction and relaxation is the blood flow through the coronary arteries the greatest
Definition
early diastole
Term
what three arterial trunks come from aorta and feed abdominal viscera
Definition
celiac: stomach
superior mesenteric: transverse colon, SI
inferior mesenteric: sigmoid colon
Term
three shunts caused by portal HTN
Definition
esophageal varices
hemorrhoids
caput medusa
Term
where is McBurney's point
Definition
1/3 ASIS to umbilicus
Term
what is the triad for peridonitits
Definition
rebound tenderness
rigidity of muscles
abdominal pain
Term
what are the layers of spermatic cord superificial to deep
Definition
skin
superificial fascia
cremasteric muscle
peritoneum (internal spermatic fascia)
tunica vaginalis (loose CT)
testies
Term
where does the ovarian artery originate
Definition
aorta
Term
compare brocas aphasia with wernickes aphasua
Definition
wernickes: cannot understand but can speek fluently

brocas: can understand but cannot speak
Term
what artery supplies the lateral cortex
Definition
middle cerebral
Term
what artery supplies the medial cortex
Definition
anterior cerebral
Term
5 signs associated with transient ischemia involving vertebrobasilar artery insufficiency
Definition
ataxia
nausea
facial muscle weakness
vertigo
diplopia
Term
what CN do taste
Definition
7, 9, 10
Term
what CN do hearing
Definition
8
Term
what CN do mastication
Definition
5
Term
what CN move trapezius
Definition
11
Term
what CN do facial expression
Definition
7
Term
what CN do sensory for viscera
Definition
10
Term
what CN connects to Ed West nuclei
Definition
3
Term
what CN connect to inferior salivary nuclei
Definition
9
Term
what CN connect to dorsal motor nuclei
Definition
10
Term
what part of striatum atrophies in huntington disease
Definition
caudate, putamen, frontal cortex
Term
what part of the brainstem is lost in parkinsons disease
Definition
substantia nigra and locus cerilleus
Term
what part of basal ganglion (and its two structures) is site of copper accumulation in wilsons disease
Definition
centicular nuclei: putamen and globus pallidus
Term
that thalamus recieves all sensory input except for one
Definition
olfaction
Term
what part of the brainstem is destoried in wallenburg syndrome, what artery causes it
Definition
lateral medulla
posterior superior cerebellar artery
Term
if contralateral body pain and temperature sensation is lost what tract has been injured
Definition
spinothalamic
Term
what occurs if the cortocospinal tract is damaged
Definition
UMN damage: decreased motor, spastic paralysis contralateral hemiparesis of trunk and limbs
Term
what lesion tops the ddx if there is muscle weakness and loss of sensation in the right arm
Definition
middle cerebral artery
Term
what lesion tops the ddx if there is muscle weakness and loss of sensation in the left leg
Definition
right anterior cerebral artery
Term
in what dermatome is the anus, umbilicus, bit toe
Definition
anus: S5
umbilucus: T10
Toe: L5
Term
if L5 transverse process articulates or is fused with the sacrum what is the disorder
Definition
sacrilization
Term
what gene makes gp41, gp120, p24, reverse transcriptase in HIV
Definition
gag: p24 (capsid)
pol: reverse transcriptase
env: gp160 > gp120 (binds CD4) + gp21 (binds CCR5)
Term
what comma shaped organism is renowned for causing ricewater stool and transmitted in contaminated water
Definition
vibro cholera
Term
what is the duration of pain for a MI
Definition
>30 min
Term
why is thromboxane a pro-coagulant
Definition
used by platelets to stick together
Term
what nerve root is tested by biceps reflex
Definition
C5
Term
if you wanted to test ROM of shoulder what would be the best
Definition
apleys scratch test
Term
what is the most common cause of brachial plexus injury, what nerve roots is it
Definition
erb duchene
C5-6
Term
what tests are positive in thoracic outlet syndrome
Definition
apleys scratch test
roo test
absens (the arm to the side and loose pulse thingy)
Term
how does adhesive capsulitis develop
Definition
injury and immobilization allows for adhesions to form in healing
Term
what is the normal carrying angle of the female arm
Definition
10-12 deg
Term
what are two primary supinators of the forearm
Definition
supinator
biceps
Term
what is the technical term for tennis elbow and strain of what group of muscles (flexors or extensors) caused it
Definition
lateral epicondylitis
extensors
Term
three tests for carpal tunnel
Definition
phallen
tinnel
prayer
Term
what nerve is entraped in carpal tunnel
Definition
median
Term
if the MCP and DIP are extended, and the PIP is constracted, what is the hand deformity
Definition
boutinneres
Term
what nerves are damaged in bishops deformity
Definition
unlar: if the pinky and ring cannot be lifted
median: if the pointer and middle are stuck up and the pt cant bend them down
Term
what is the main difference in the mechanism of action between straptoinase and TPA
Definition
TPA only lyses thrombin that is already bound(causes less unintended bleeding)
streptokinase lyses all thrombin
Term
what is the general mechanism of the 4 classes of anti arrhythmic drugs
Definition
1) decreases Na
2) BB
3) decreases K
4) CCB
Term
what two classes of inotropic agents do digoxin and digitoxin belong
Definition
glycocides
Term
what is the formula for calculating mean blood pressure
Definition
systole - 1/3(systole-diastole)
Term
what is the formula for calculating CO
Definition
CO = SV x HR
Term
what is the formula for calculating TPR
Definition
TPR = MAP / CO
Term
what is the formula for calculating renal clearance
Definition
C = (solute in urine x volume in urine) / solute in plasme

AKA C = (pee x pee) / blood
Term
which regulates bicarbonate and which regulates CO2, kidney or lung
Definition
lung CO2
kidney bicarbonate
Term
what is the formula for elasticity
Definition
E = 1 / compliance

E = change in pressure / change in volume
Term
what is the formula for compliance
Definition
C = change in volume / change in pressure
Term
what ion channel is open in upstroke of action potential
Definition
Na
Term
is the Na/K channel active, facillitated, or secondary active transport. what about Na/glucose
Definition
Na/K - active
Na/glucose - facillitated
Term
what is the major PROPHYLACTIC agent for asthma
Definition
chromolyn
Term
what 2 receptor types if stimulated result in cAMP increase
Definition
beta and histamine
Term
what 3 hormones or drugs increase cGMP
Definition
NO
ANP
viagra
Term
with G proteins which one inhibits adenylate cyclase, which stimulates it, which activates phospholipase C
Definition
Gi inhibits
Gs stimulates
Gq phospholipase C
Term
what type of nerve fiber innervates skeletal muscles
Definition
Nm
Term
what is the diameter of a skeletal muscle fiber in comparison with others
Definition
large, myelinated, fast A-alpha fiber
Term
what two types of nerve fibers are involved with afferent and efferent innervation of muscle spindles
Definition
afferent: alpha 1 and 2
efferent: gamma
Term
what touch receptors sense pressure, touch, pain/temp, vibration
Definition
pressure: merkel
touch: meissners, follicle sensors
vibration: pancinian
temp: free nerve endings
pain: free nerve endings
Term
describe the elasticity in presbyopic patients
Definition
decreased elasticity due to aging
(need reading glasses)
Term
does the slow or fast phase of eye movement determine direction of nystagmus
Definition
fast
Term
what are the results of the rinne and webber in conduction deafness
Definition
webber: lateralize to the bar ear bc not distracted by other sounds
rinne: BC > AC
Term
what does sympathetic stimulation do to bronchi, GI sphincters, pupils, GI motility
Definition
bronchi: dilate
sphincter: contract
pupil: mydriasis (contract iris dilator)
motility: decrease
Term
which cholinergic receptors are on sweat glands
Definition
muscarinic
Term
which adrenergic receptor causes bronchidilation, presynaptic sympathetic inhibition, sympatheitc stimulation in heart, vasoconstriction in the GI tract
Definition
bronchodilation B2
presynapse inhibition A2
sympathetic heart B1
vasocon Gi A1
Term
what is the parasympathetic stimulation of the SA/AV in the heart, what does it cause to happen
Definition
left vagus: AV node decreased conduction and atrium contraction

right vagus: SA node decrease frequency
Term
what component of muscle measures the muscle length
Definition
spindle
Term
when the muscle spindle is activated what does it do to the muscle
Definition
activate it (causes pain and tightness)
Term
which has higher glycolytic capacity red or white skeletal muscle
Definition
white
Term
what does Ca bind to in activating skeletal muscle, smooth muscle, and heart muscle
Definition
skeletal: traponin C
smooth: calmodulin
heart: traponin C
Term
what does the a wave represent in assessing cardiac pressure
Definition
atrial filling
Term
in what part of the lung is perfusion the greatest, where is ventilation the greatest
Definition
base (area 3): perfusion > ventilation
apex (area 1): ventilation > perfusion
Term
what level of te brainstem may a transection occur that will have no effect on respiration
Definition
midbrain
Term
what adrenal disorder has overproduction of androgens
Definition
11 and 21 enzyme thingy deficiency (virilization)
Term
what adrenal disorder has overproduction of mineral corticoids
Definition
17 enzyme thingy deficiency (conns)
Term
what adrenal disorder has over production of glucacorticoids
Definition
21 enzyme thingy deficiency (cushings)
Term
what is the primary motion of T11 and T12
Definition
flexion and extension (the rest of the thoracic is rotation!!)
Term
what rib dysfunction has the ribs stuck down, what is the restriction, what is the key rib
Definition
dysfunction: inhaled
restriction: exhaled
key: bottom rib
Term
what gender is dysplastic spondylolisthesis most common, what type of spondylolisthesis is it, when does the initial deficit occur
Definition
F>M
type 1
congenital, birth it is present
symptomatic 7-9yo
Term
what is the first line drug for newly diagnosed DM2
Definition
metformin
Term
what defect results in each hyperlipidemia: 1, 2a, 2b,
Definition
1) LPL deficiency
2a) LDL receptor defect
2b) b100 defect
3) apo E deficiency
4) VLDL and underutilization
Term
how many kcal/g of energy is made by the metabolism of carbs, fat, proteins
Definition
carb 4
fat 9
protein 4
Term
what is the primary disturbance causing respiratory acidosis and metabolic acidosis
Definition
respiratory CO2
metabolic decreased bicarb
Term
what are the two normal Hb in an adult
Definition
HbA (a2, B2)
HbA2 (a2, gamma2)
Term
what Hb is elevated in hyperglycemia
Definition
HBA1C
Term
4 situations that reduce O2 binding to Hb
Definition
acidic
CO
increased temp
1,3-DPG
Term
what are the two primary functions of albumin
Definition
carry lipid soluble things in the blood
create oncotic pressure to draw water in
Term
which part of the circulatory system holds the largest volume of blood, which has the greatest cross sectional area, which has the most resistance
Definition
largest: veins
area: capillaries
resistance: arteriOLES
Term
what two vessels does the ductus arteriosus connect, if patent what body part recieves full oxygendation despite PDA
Definition
pulmonary artery and aorta

head and upper extremities because the PDA comes after the first branches off the aorta
Term
at what part of the renal tubule do carbonic anhydrase inhibitors function, loop diuretics, and thiazides
Definition
CA: PCT
loop: thick descending limp of henle
thiazide: DCT
Term
what part of kindy resorbs glucose and AA, which secretes K
Definition
resorbs: PCT
secretes: collecting duct
Term
what is the normal value of GFR
Definition
125 mL/min
Term
is the ICF increased decrease or unchanged in hypotonic dehydration, hypotonic hydration, isotonic dehydration
Definition
hypotonic dehydration: increased
hypotonic hydration: decreased
isotonic dehydration: no change
Term
in what part of kidney is the macular densa, what does it sense
Definition
DCT, Na concentration decreases
Term
what is the renin level in Bartter's syndrome, what is the BP
Definition
high renin
normal BP
Term
what metabolic process does niacin prevent in adipocytes, what is the primary adverse drug reaction
Definition
stops lipoprotein lipase
flushing, puritis
Term
what enzyme is inhibited by statins
Definition
HMG-COA reductase
Term
cimetidine and ranitidine block what receptor
Definition
H2
Term
what molecule transports Fe
Definition
transferrin
Term
what molecule stores Fe
Definition
ferritin and hemosiderin
Term
what are the main products of mucous cells, parietal cells, and chief cells
Definition
mucous: bicarbonate, mucous
chief cells: pepsinogen
parietal cells: HCl, intrinsic factor
Term
what is the direct result of secretin release
Definition
stomach motility
bicarb pancreas secretion
Term
what is the direct result of CCK release
Definition
pancreatic exocrine secretion
gallbladder contraction
Term
what disease is defined by hyperaldosteronism
Definition
ALD producing adenoma (Conn's syndrome)
Term
effects insulin has on liver metabolism
Definition
increases glyconeogenesis
decreases gluconeogenesis
decreases glycogenolysis
decreases FA oxidation
increases lipogenesis
Term
what age does separation anxiety occur
Definition
9mo
Term
what age does a baby sit alone
Definition
7mo
Term
what age does a baby stand holding onto nearby objects
Definition
10mo
Term
what age does a baby stand alone
Definition
14mo
Term
what ages does a baby walk alone
Definition
15mo
Term
what is an average IQ
Definition
100
Term
what are the IQ ranges for mild MR, moderate MR, severe MR, and profound MR
Definition
mild: 55-79
mod: 40-55
severe: 25-40
profound: <25
Term
define operant conditioning
Definition
permanent effects
punishment for behavior
Term
define classical condtioning
Definition
effects do not last
rewarded for good behavior
works better on reflexive behavior
Term
what do nodules (micro/macronodular) indicate about the liver
Definition
had liver injury and regeneration
Term
what vertebral level is the sternal notch
Definition
T2
Term
at what vertebral level is the sternal angle
Definition
T4
Term
what is the main motion in assessing the OA
Definition
sideslipping/translation
Term
what type of hypersensitivity has uticaria, erythema, bronchiole constriction
Definition
1
Term
what AB is associated with RA, SLE, celiac, and wegeners
Definition
RA: anti-IgG aka RF
SLE: anti-dsDNA, anti-smith
celiac: anti-glidan
wegeners: c-ANCA
Term
what type of cell is stimulated by IL4 and IL5
Definition
B cell
Term
what effect does NO have on the vessels
Definition
vasodilation
Term
what is the moa dipyridamole, why is it used
Definition
decreases PDE which decreases TXA2 which decreases platelet ADHESION

with warfarin: decreases clots in replacement valves

with aspirin: chronic platelet adhesion prevention

radiotracers: stress tests
Term
what is the MOA doxorubicin, what is the classic side effect
Definition
decreases topoisomerase II which makes Fe ROS by decreasing IP3

cardiotixicity, red urine
Term
what disease is endemic to south west US and is arked by fever, cough, arthralgia
Definition
coccidioidomycosis / valley fever
Term
what disorder has personality changes, intelluctual deterioration, autonomic motor dysfunctions, and occurs as a result of HIV infection
Definition
HIV encephalopathy
Term
what are the 3 antibiotics most common to cause pseudomembranous collitis
Definition
clindamycin
cephalosporin
ampicillin
Term
largest joint in the body
Definition
tibiofemoral
Term
primary hip flexor
Definition
iliacus
Term
primary hip extensor
Definition
gluteus maximus
Term
ligament of the knee that connects to the ant tibia and post femur
Definition
anterior cruciate
Term
ligament of the knee that connects to the post tibia and the ant femur
Definition
posterior cruciate
Term
ligament of the knee that prevents knee hyperextension
Definition
anterior cruciate
Term
what does a positive anterior drawer test indicate
Definition
torn ACL
Term
test for a meniscus injury
Definition
apleys compression
mcmucrrys
Term
2 divisions of the sciatic nerve
Definition
tibia and femoral (peroneal)
Term
what nerve roots make the femoral nerve
Definition
L2-3
Term
a patient complains of superificial knee pain on medial aspect of the leg half way between the ankle and the knee, what dermatome is it
Definition
L4
Term
what dermatome is the big toe
Definition
L5
Term
achilles reflex is what nerve root
Definition
S1
Term
patellar reflex is what nerve root
Definition
L4
Term
what degree of angulatioon for the femoral head is normal
Definition
120-135
Term
what degree of angulation for the Q angle is normal
Definition
10-12
Term
what are the three positions of pronation
Definition
dorsiflex
external rotation
abduction
Term
a pt presets with supinated right foot what can be said about the fibular head
Definition
posterior
Term
what nerve can be damaged by a posterior fibular head
Definition
peroneal
Term
what is the most common compartment syndrome
Definition
anterior
Term
pt presents with ankle sprain, there is trace laxity, only involves that anterior talofibular ligament, what is the degree and type of sprain
Definition
degree 2
type 1
Term
what are the components of odonahues triad
Definition
medial meniscus
medial collateral
ACL
Term
which position of the ankle is most stable
Definition
dorsiflexion
Term
which set of ligaments are the most common involved in ankle sprains
Definition
lateral ligaments
Term
what kind of blocker is prazosin
Definition
a1 antagonist
Term
MOA clonidine
Definition
central a2 agonist
Term
what receptors do dobutamine, dopamine, and isoproterenol stimulate
Definition
dobutamine B1
dopamine D1 B1
isoproterenol B1 B2
Term
MOA metoprolol
Definition
blocks B1 receptors
Term
what cholenesterase inhibitor is used to test for myasthenia gravis
Definition
endonorphium
Term
MOA organophosphates
Definition
irreversible acetylcholinesterase inhibitors
Term
what is the difference between denial and repression
Definition
denial: pretending like it didnt happen even though you know it did

repression: auctally not remembering it happened, supression of emotion and memory
Term
when does REM begin when a nacroleptic falls into a narcoleptic state
Definition
immediatly
Term
what is the difference between central and obstrictuve sleep apnea
Definition
central: medulla chemoreceptors are not sensing or not working

obstructive: physical block
Term
list the 5 stages of dying
Definition
denial
anger
barganing
depression
acceptance
Term
what neurotransmitters are high or low in schizophrenia, depression, alzheimers, anxiety
Definition
schizophrenia high DA
depression low SE/DA/NE
alzheimers low DA high ACh
anziety low GABA
Term
compare conciousness, speed on onset and reversibaility of delirium and dementia
Definition
delirium: acute, reversible, some conciousness

dementia: chronic, irreversible, concious
Term
personality type where someone feels better than others all the type
Definition
narrassistic (ciara)
Term
personality type with dramatic emotion personality that may have some level of sexual promiscuity
Definition
histrionic (nick)
Term
what category of disorders are phobias, agoraphobia, PTSD in
Definition
anxiety
Term
how does the duration of symptoms compare between somatization and conversion disorder
Definition
somatization lasts years
conversion lasts days to weeks
Term
if a schizophrenic presents with hallucinations and delusions what type of symptoms are these classified as under heading of schizophrenia
Definition
positive
Term
at what point in the night does a person with major depression have the most difficulty remaining asleep
Definition
early morning waking
Term
what type of epilepsy is marked by 3sec spike and domes on EEG during attack
Definition
absence seizure
Term
what are the two major signs of opioid intoxication
Definition
euphoria
apathy
Term
what are 4 major signs of opioid withdrawal
Definition
nausea/vomiting
sweating
fever
muscle aches
Term
4 risk factors for physical child abuse
Definition
parent hx of abuse as child
poverty
premature or low birth weight
parent drug abuse
Term
2 risk factors for sexual child abuse
Definition
single parent home
parent does drugs
Term
what percent is included in +/-1, +/-2, +/23 standard deviation
Definition
1: 68%
2: 95%
3: 99%
Term
probability that a negative test result is actually negative
Definition
negative perdective value
Term
probability that a positive test result is actually positive
Definition
positive perdictive value
Term
probability an ill patient will have a positive test
Definition
sensitivity
Term
probablity a healthy patient with have a negative test
Definition
specificity
Term
what is the term for the number of people who have a specific disease at a given point in time per 100,000 people
Definition
prevalence
Term
what is the term for the number of new people that develop a specific disease in a year per 100,000 peple
Definition
incidence
Term
in a randomized clinical trial what type of error results in rejection of the null hypothesis even though the null hypothesis is true
Definition
1 or alpha
Term
in observed cohort what is the term for ability of a test to test what is ment to test
Definition
validity
Term
what is the term for how well the test results can be reproduced
Definition
relability
Term
what two components are needed for someone to be involuntairly treated
Definition
mentally ill
AND
in danger of self or others
Term
what 4 situations are parental consent not needed in treatment of a minor
Definition
emergency
pregnancy
STF
judge determined
Term
what government insurance is for the poor
Definition
medicaid
Term
what government insurance is for the elderly
Definition
medicare
Term
what type of bladder is created by spinal cord damabe above the sacral cord
Definition
spastic autonomic
Term
what type of bladder is created by damage of the sensory nerves flaccid
Definition
atonic bladder
Term
what are three major drugs that enhance NMJ blockers
Definition
CCB
halothane
aminoglycocides
Term
what is a common indication for scopolamine use
Definition
motion sickness
Term
what are 6 major SE of estrogen treatment
Definition
nausea
vomiting
endometrial hyperplasia
DES- clear cell CA in daughters
Term
3 main SE of progesterone tx
Definition
hirsturism
increased LDL and decreased HDL
weight gain and acne
depression
Term
what type of blood and liver disorder can result from OPCs
Definition
tumor of liver benign adenoma

clots
Term
what color are gram positive after gram stain
Definition
first step: crystal violet stains blue purple
last step: safranin changes it to blue violet
Term
what triggers classical and alternate pathway for complement system
Definition
classic: antigen antibody complexes

alternate: endotoxin, cobra venom, fungi capsules
Term
compare botulinum toxin and tetanospasmin where is it made
Definition
botulinum: muscle flaccid, produced in body

tetanus: muscle spasm, preformed toxin
Term
compare and contrast hypotonic dehydration and hypertonic dehydration in terms of ICV and ECV and causes
Definition
hypotonic: increased ICV, decreased ECV, osmotic diarrhea, vomiting, addisons (Na loss)

hyper: decreased ICV, increased ECV, sweat, DI (water loss)
Term
what organ is ACE found in
Definition
lung
Term
what part of the nervous system is activated by LSD
Definition
sympathetic
Term
what is the street drug that causes agressive, fearless behavior
Definition
phencyclidine
Term
what opioid receptors causes analgesia, sedation, and respiratory depression
Definition
analgesia and respiratory depression - Mu
sedation - kappa
Term
besides pain control what can codine do
Definition
antitussive
Term
how does fentanyl compare to morphine in potency
Definition
more
Term
what neurotransmitter does TCA block
Definition
NE SE
Term
what are 3 foods high in tyramine
Definition
cheese
beer and wine
liver
Term
what are indications for use of lithium
Definition
bipolar
mania
Term
what is the effect of nicotine on blood pressure
Definition
low dose increases it
high dose decreases it
Term
what type of reflex is define as visceral stimuli by making a response in somatic structures innervated by the same vertebral segment
Definition
viscerosomatic
Term
what type of reflex is occuring when a chronic biceps strain results in respiratory difficulties secondary to diaphragm dysfunction
Definition
somatiovisceral
Term
what is then sympathetic collateral ganglion associated with the greater splanchnic nerve
Definition
celiac
Term
what is the sympathetic collateral ganglion associated with the lesser splanchnic nerve
Definition
superior mesenteric
Term
what is the sympathetic collateral ganglion associated with the least splanchnic nerve
Definition
inferior mesenteric
Term
what nerve root innervates the small intestine with the exception of part of the duodenum
Definition
T10-11
Term
if a pt had an ovarian cyst you might have dysfunction in visceral or somatic structures innervated by what nerve root? what cutaneous landmark would be included in possible reflex sites in the aformentioned situation
Definition
T10-11
umbilicus
Term
what effect does PS has on papillary muscles
Definition
meiosis
Term
what is the result of PNS on the adrenal medulla, GI sphinctors, and penis
Definition
medulla - none
relax GI sphinctors
erect penis
Term
what is the result of sympathetic stimulation of the skeletal muscle, arteries, salivary glands, and intestines
Definition
muscle: increased glycogenolysis
constrict arteries in skin (a1)
relax arteries in muscles (B2)
thicken salivary secretions
decrease motility and secretion
Term
what are 5 major physiologic effects that stimulated H1 receptors have
Definition
nasal and bronchial mucous
bronchiole constriction
intestinal smooth muscle contraction
stimulate sensory nerve endings
vasodilation
Term
what is the main physiologic effect of stimulated H2
Definition
increase HCl inthe stomach
Term
what anesthetic agent has the potential to cause malignant hyperpthermia
Definition
all
Term
besides supporting homeostasis, maintaing healthy metabolism, and supporting the whole patient what is the FIRST step in treating any dysfunctions involving facillitated spinal cord segments
Definition
treat dysfunctional segment
Term
after treating the dysfunctional segment, what are the next three steps in treating a facillitated dysfunction
Definition
decrease hyperSNS
fluid balance
manage PNS
Term
describe how rib raising has effect it does
Definition
alters pressure on sympathetic chain
fascia eound rib head is same as around sympathetic chain
Term
in decreasing sympathetic contribution to a facilitated segment, what structures should be assessed after rib raising
Definition
sympathetic ganglia
Term
name the collateral ganglia
Definition
preaortic
celiac
superior mesenteric
inferior mesenteric
cervical
Term
why do all cervical ganglia result in heart problems
Definition
they all contribute to the cardiac plexus
Term
which chapmans points are used for assessment and which for treatment
Definition
anterior assess
posterior treat
Term
where is the chapmans reflex point for the sinuses
Definition
inferior clavicle
Term
where is the chapmans reflex point for the liver
Definition
costeosternal of 5 and 6 on right
Term
where is the chapmans reflex point for the appendix
Definition
tip of rib 12
Term
where is the chapmans point for the retina
Definition
superolateral humerus
Term
what structures comprise the clinical throacic inlet
Definition
rib 1
manibrum
T1
Term
what 4 diaphragms should be assessed and released when adressing lymph drainage
Definition
cervicothoracic
craniocerivcal
pelvic
abdominal
Term
what should always be done first lymph pumps or diaphragms
Definition
diaphragms
Term
what are 4 anatomic transition sites of fascia, in common compensatory which way to each go
Definition
craniocervical - left
cervicocthoracic - right
thoracolumbar - left
lumbosacral - right
Term
what nerve roots make the pelvic splanchnic nerve
Definition
S2-4
Term
what is the parasympathetic innervation to the mucous membrane of the sinuses and nasal mucosa
Definition
CN 7
Term
what cranial nerve is affected by manipulation of the sphenopalatine gangliona
Definition
CN 7
Term
what structure may be manipulated to balance the vagus nerve
Definition
OA, AA, C2
Term
what is the sympathetic innervation to the pancreas
Definition
T7 right
Term
what is the symptathetic innervation to the gallbladder
Definition
T6 right
Term
what is the primary method for modulating the pelvic splanchnic nerves
Definition
sacral rocking
Term
what are the three components of the primary respiratory mechanism
Definition
CSF, meninges, bones
Term
what are the dural attachments
Definition
cranial bones
foramen magnum
C2-3
S1 posterior
Term
in craniosacram extension what happens to the midline bones and cranial diameter and sacrum
Definition
midline paired bones internally rotate
nutation of sacrum
increased AP diameter
Term
in cranial torsion what is the dysfunction named for
Definition
greater wing of sphenoid that is superior
Term
what is the purpose of th eCV4 method
Definition
increase CRI by decompressing the SBS
Term
what type of cranial dysfunction is marked by cephalic deviation of the sphenoid
Definition
superior vertical strain
Term
DOC petit mal seizure, aka
Definition
ethosuxamide
absence
Term
DOC status epilepticus
Definition
diazepam
Term
DOC vertigo
Definition
meclizine
Term
DOC chemo nausea
Definition
metoclopramide and odanzatron
Term
DOC motion sickness
Definition
scopolamide
Term
effect magnasium, why
Definition
diarrhea, draws water in via osmosis
Term
to what calss of drugs (2 answers) to lorazepam, diazepam, triazolam and chlordiazepoxide belong
Definition
anoxiolytic
benzodiazepines
Term
barbituates have high suicide potentional, what is the common way for them to cause death in overdose
Definition
decrease chemoreceptor response to CO2 causing hypoxia
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