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SEnsory Perception (pharm)
term/ definitons/questions
49
Pharmacology
Undergraduate 1
10/07/2013

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Term
Lubricants
Definition
moisten and maintain epithelial surface.

can be bought over the counter
Term
Example of diagnostic aid?
Definition
Dyes
Term
Cholinergic agents (Miotics)
Definition
lower intraocular pressure

increase blood flow to retina

decrease retinal damage and loss of vison
Term
what are the two types of cholinergic agents?
Definition
direct acting cholinergics

indirect acting cholinergics
Term
Example of cholinergic agent
Definition
Pilocarpine- which cause constricition of the pupil and increases intraocular pressure.
Term
Side effects of Cholinergic agents
Definition
headache
eye pain
decrease vision
can become toxic
vertigo
decrease heart rate
decrease b/p
seizures
Term
What is the antidote of Cholinergic agents?
Definition
Atropine
Term
Nursing considerations for cholinergic agents
Definition
apply pressure on lacrimal duct to inhibit drug entering the systemic circulation

contraindicated with retinal detachment

caution with asthma, htn, corneal abrasion, hyperthyroidism, cvd

treat overdose with Atropine.
Term
Beta adrenergic Blockers
Definition
***First line drug choice for the treatment of glaucoma.
Term
What doea Beta Blockers do for glaucoma?
Definition
decrease production of aqueous humor- exact mechanism is unknown.
Term
Examples of Beta Adrenergic Blockers?
Definition
Betaxol Hcl (betoptic)
Carteolol Hcl (ocupress)
Levobunolol HCl (Timoptic)
Term
Prostaglandin analogues
Definition
is effective like beta blockers with the side effects.

lowers intraocular pressure
increase outflow of aqueous humor
Term
Examples of Prostaglandin analouges
Definition
latanoprost (xalatan)
Bimatoprost (lumigan)
Travoprost (travatan)
Term
Side effects/adverse reactions of Prostaglandin Analogues
Definition
*brown pigmentation esp. with green/yellow irises +permanent+
*growth of eyelashes
*blurred vision
*conjunctivitis
*dry eye
*tearing
*light intolerance
Term
Carbonic Anhydrase Inhibitors
Definition
interfere with production of carbonic acid

decrease aqueous humor formation

decrease intraocular pressure
Term
Nursing considerations for CAI's
Definition
use only when pilocapine, beta blockers, epinephrine, and cholinesterase inhibitors are not effective.

allow 5 to 10 minutes before applying another medication.
Term
Example of CAI's
Definition
Acetazolamide (Diamox)
Term
Side effects of CAI's
Definition
do not use in 1st trimester
do not use if allergic to sulfonamides
lethargy
anorexia
drowsiness
paresthesia
depression
polyuria
nausea and vomiting
hypokalemia
renal calculi
Term
Osmotics
Definition
used for preop and postop

decreases vitreous humor volume

rapidly decreases intraocular pressure
Term
examples of osmotics
Definition
Glycerin (Osmoglyn)
Isosorbide (Ismotic)
Mannitol (Osmitrol)
Term
Side effects of Osmotics
Definition
headache
nausea and vomiting
diarrhea
disorientation due to electrolyte imbalance
Term
Anticholinergic, Mydriatics and Cycloplegics
Definition
used in diagnostic procedures and ophthalmic surgery
Term
mydriatics
Definition
dilate the pupils
Term
cycloplegics
Definition
paralyze the muscles of accommodation
Term
anticholinergics
Definition
dilate pupils and paralyze muscles of accommodation
Term
Anticholinergic, Mydriatics, Cycloplegia
Definition
atropine sulfate
epinephrine hcl (epifrin, glaucon)
tropicamide (mydriacyl ophthalmic)
Term
Side effects of adrenergic mydriatics

Nursing consideratons
Definition
headache
brow pain

contraindicated in pts with cardiac dysrhythmias, cerebral atherosclerosis, bph, diabetes, parkinsonism

pt to notify hcp of blurred vision, loss of sight, difficulty breathing , increase perspiration, and flush
Term
Side effects of cycloplegia
Definition
tachycardia
photophobia
mouth dryness
edema
conjunctivitis
dermatitis

signs of atropine toxicity: dry mouth, blurred vision, photophobia, constipation, fever, tachycardia, confusion, halluncinations, delirium, coma

contraindicated in pt with glaucoma- increase intraocular pressure
Term
Macular degeneration
Definition
is the leading cause of vision loss over 65.
Term
what type of vision is the macula responsible for?
Definition
sharp, central vision
Term
2 types of Macular degeneration
Definition
wet-growth of abnormal blood vessels behind the retina shifting macula from normal position; progresses rapidly; 10-15% of cases; wet develops from dry

dry- slowly destroys vision over a period of years. 85-90% of cases; gradual destruction of light sensitive cells leading to blurred vision or blind spot
Term
treatment of macular degeneration
Definition
laser; photodynamic
medications: stabilizes vision
Term
Patient teaching for macular degeneration
Definition
make sure the pt is listening to you
give them the time , instructions and let them do a return demonstration
1 drop is the typical dose
2nd drop is an overflow; too much
wait 5 minutes between drops
maintain sterility of the dropper
store in light resistant container; cool place
do not stop meds without HCP approval
if they have glaucoma that should avoid atropine like drugs
check labels on all otc drugs
carry a medical alert id bracelet.
Term
Otic (ear)
Definition
commonly used for:
acute otitis media
acute otitis externa (swimmer's ear)
Term
Examples of Otic drugs
Definition
polymixin B- ** first line of drug treatment

tetracycline(achromycin)

erythromycin (e-mycin)
Term
side effects of Otic medications
Definition
overgrowth on non susceptible organisms
Term
Antihistamine (decongestants)
Definition
reduces nasal and middle ear congestion in acute otitis media

reduce edema around orifice of Eustachian tube-promotes drainage from middle ear
Term
Examples of Antihistamines
Definition
Actifed
Allerest
Dimetapp
Ornade
Phenergan
Triaminic
Term
Side effects of Antihistamines
Definition
drowsiness
blurred vision
dry mucous membranes
Term
Ceruminolytics
Definition
loosen and remove impacted ceremun from ear canal.
Term
examples of Ceruminolytics
Definition
cerumenex, debrox(otc)
Term
Alternatives to loosen cerumen:
Definition
irrigate with hydrogen peroxide
if chronic?- 1-2 drops of olive oil or mineral oil
Term
Patient teaching for Ear care
Definition
*no foreign objects in ear
*take drugs as prescribed
*keep drug in light resistant container
*instruct the patient about expected drug effect, dosage, side effects, administration technique and also when to notify the HCP
Term
Dermatitis(drug-induced)
Definition
is an adverse reaction to drug therapy

rash, urticarial, papules, vesicles to life threatening erythema multiforme blisters, steven Johnson syndrome, and epidermal necrolysis.

last drug given

lupus like symptoms

antibacterial/anticonvulsnats -(exfoliative dermatitis) cause erythema, itching, scaling, loss of body hair

sulfa antibiotics- epidermal necrolysis
Term
Contact dermatitis
Definition
cause by chemical or plant irritation

skin rash, itching, swelling, blistering, oozing, scaling
Term
Treatment for contact dermatitis
Definition
topical exposure- clean skin immediately!

topical- calamine lotion

systemic- Benadryl and periactin

antipruritic bath- oatmeal or alpha-keri

solutions of potassium permanganate, aluminum subacetate, Ns

glucorticoid ointments, creams, gels- can be absorbed systemically.
Term
Burns
Definition
use Silvadene cream (silver sulfadiazine)
Term
Silvadene cream
Definition
prevents and treats sepsis in 2nd and 3rd degree burns

acts on cell membrane and cell wall to produce bactericidial effects

1% or less of silver is absorbed; 10% of sulfadiazine is absorbed
Term
Nursing consideration for Silvadene Cream
Definition
Watch for crystalluria

side effects: skin discoloration, burning, rashes, erythema, skin necrosis, leukopenia
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