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Scientific Literature
Quiz 4 (6.18)
25
Other
Not Applicable
06/13/2008

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Term
Single Blind Experiment:
Definition
EITHER the observer of the measurements does not know OR the subject of the experimental treatment does not know in which group (experimental or control) the subjects have been placed
Term
Double blind Experiment
Definition
NEITHER the researcher NOR the subjects know who is receiving the experimental or placebo treatment
Term
Bias
Definition
anything that mistakenly influences the conclusions about groups and distorts comparisons.
Term
Subject Selection Bias
Definition
Inappropriate selection of study subjects; often leads to incorrect relationships between risk factor(s) and disease
Term
misclassification bias
Definition
Inappropriate collection of information during the study; often leads to incorrect relationships between risk factor(s) and disease
Term
confounding bias
Definition
some known or unknown factor is associated with both the risk factor and the outcome; often leads to incorrect relationships between risk factor(s) and outcome (disease)
Term
case control
Definition
study design in which persons with a disease of interest (cases) are compared with those without the disease (controls); researchers look back to identify possible causes
Term
case report
Definition
a professional article that describes the diagnostic, preventive, and therapeutic services rendered to a patient with an unusual or complex condition
Term
case study
Definition
a journal article that describes a series of cases of an unusual or complex condition
Term
clinical trial
Definition
An experiment designed to test the effect of an agent or procedure on two or more groups
Term
cohort
Definition
group of individuals with similar characteristics
Term
cohort study
Definition
study where the same subjects are followed over a period of time to observe the occurrence of a particular event
Term
control group
Definition
Group that does not receive the independent variable (may receive a placebo or no treatment at all). An equivalent group used for comparison
Term
cross sectional study
Definition
descriptive study where variable(s) is/are measured at one point or limited period or time
Term
intervention trial
Definition
Study conducted on a population (i.e. entire city) where independent variable is either added or removed and the outcome is measured
Term
longitudinal study
Definition
An investigation of similar groups of individuals over an extended period of time in order to identify a change or development in that group
Term
quasi-experimental
Definition
research design that attempts to approximate the standards of experimentation, but falls short of the control and precision required; random assignment of participants is not possible
Term
research design
Definition
framework or blueprint for conducting a study
Term
sample
Definition
A subset of measurements selected from a population of interest. A part or subset of the population used to gain information about the whole
Term
census
Definition
sample consisting of entire population
Term
convenience
Definition
subjects chosen from whatever portion of the population is easiest to reach
- access to total is not possible
- risk of bias
Term
judgemental
Definition
someone with knowledge of population arbitrarily selects the sample to represent the population
- risk of bias
Term
random
Definition
subjects chosen in such a way that every member of the population has an equal chance of being selected to be in the sample
- increases external validity
- reduces chance of bias
Term
stratified random
Definition
subjects chosen from subgroups proportionately in the sample with similar characteristics
Term
systematic
Definition
every nth member of population is selected; ā€œnā€ can represent any number; essentially equivalent to simple random sampling
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