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Science 1000c STJ
Infectious Disease and the Immune System, STJ
383
Science
Undergraduate 1
03/12/2013

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Term
Science is derived from this word:
Definition
Scientia
Term
Scientia:
Definition
Knowledge
Term
Science is the:
Definition
Idea of testing and gathering information
Term
Science is based on the:
Definition
5 senses
Term
Science began to take more precedence once:
Definition
Doubt in Christianity began to emerge
Term
"Infectious":
Definition
An agent causes a disease that harms the body, can be spread through personal methods
Term
Contagious:
Definition
Communicable, spreads person to person
Term
Infectious disease can be:
Definition
contagious
Term
Infectious disease can be spread by:
Definition
- Fungus
- Virus
- Bacteria
- Parasites
- Prions
Term
Bacteria can cause:
Definition
Lyme disease (ticks) and Pink eye
Term
Parasites can cause/create:
Definition
"worms"
Protists
Amoebas
Protozoans
Term
Prions can cause:
Definition
Mad cow disease
Term
What causes Mad Cow Disease?
Definition
A strain of protein found in a cows brain that negatively impacts a humans body when digested
Term
The Flu is caused by a _____ and can be prevented with a _______.
Definition
Virus
Vaccine
Term
Tuberculosis is caused by ______ and can be treated with ______.
Definition
Bacteria
Antibiotics
Term
Cholera is caused by ______ and can be treated with ______.
Definition
Bacteria
Antibiotics
Term
HIV/AIDs is caused by a _____ and can be treated with _______
Definition
Virus
Nothing
Term
Malaria is caused by _______ and can be treated with _________.
Definition
Protozoan
Nothing
Term
Measles are caused by ______ and can be treated with ______.
Definition
Virus
Vaccine
Term
Hepatitis B is caused by ______ and can be treated with _______
Definition
Virus
Vaccine
Term
Whooping cough/Pertussis is caused by _______ and can be treated with _______.
Definition
Bacteria
Vaccine
Term
Tetanus is caused by _______ and can be treated with _________.
Definition
Bacteria
Vaccine
Term
Dengue/Hemorrhoids are caused by ________ and can be treated with _______
Definition
Virus
Nothing
Term
Blood shelf life is only:
Definition
42 days
Term
Blood platelets:
Definition
Can be frozen
Term
Blood plasma/serum:
Definition
Fluid part of blood, can be frozen
Term
Red blood cells:
Definition
Limited shelf life
Term
White blood cells:
Definition
Unique to each person, cannot be transferred from one person to another.
Term
Blood proteins:
Definition
Clotting factors of blood
Term
Those with hemophilia lack:
Definition
blood proteins
Term
In 1918, Landsteiner:
Definition
Develops blood typing system
Term
Mixing incompatible blood results in:
Definition
coagulated (jello-like) blood
Term
True/False: O blood can be transferred to people of all blood types
Definition
True
Term
If both parents have a negative Rh factor,
Definition
Their child will have a negative Rh factor
Term
What does the term "Rh" come from?
Definition
Rhesus Monkey, Landsteiner did his blood tests on monkeys
Term
If you have a positive Rh factor:
Definition
your blood would clot the monkey blood (bad)
Term
If you have a negative Rh factor:
Definition
your blood wouldn't clot the monkey blood (good)
Term
_____ of the world population has a positive blood type
Definition
75%
Term
Your blood type is your:
Definition
Phenotype
Term
In the 1850s, Mendel:
Definition
studied empiric senses
Term
Your genotype is:
Definition
what is on your alleles to define the trait
Term
Our DNA is on our:
Definition
chromosomes
Term
Everyone has ___ alleles on every ___ gene
Definition
2
1
Term
Every person has ____ chromosomes which divides into ____ pairs
Definition
46
23
Term
Women have two:
Definition
XX Chromosomes
Term
Men have:
Definition
an X and a Y chromosome
Term
If your blood type is AB, then on your alleles:
Definition
you have A on one allele and B on the other
Term
If you have an A or a B blood type, what are the two possible bloodtypes on your alleles?
Definition
AA or AO
BB or BO
Term
Can a woman with Ao blood and a man with Oo blood give birth to a son with B blood? Why?
Definition
No because B is not dominant on any of their alleles
Term
What is the possible blood type of the child of a mother with Ao blood and a father with Oo blood? Why?
Definition
Ao or Oo because A and O are both dominant on the parents alleles and o is also recessive on both of their alleles
Term
IVF stands for:
Definition
In Vitro Fertilization
Term
How can IVF be taken care of?
Definition
Implanted into the body
Kept frozen
Term
What do Human Leukocyte Antigens do?
Definition
They can tell what naturally is from and belongs in the body and what is foreign
Term
In order to receive any form of transplant from someone else, what must match up?
Definition
All of the Human Leukocyte Antigens on the chart
Term
What is on the Human Leukocyte Antigens list?
Definition
A, B, C, DR, DP, DQ
Term
You receive _____ HLA from your mom and _____ from your dad.
Definition
6
6
Term
Your perfect match is:
Definition
yourself and your twin
Term
If you have leukemia, what's a possible source of a transplant?
Definition
Your own bone marrow
Term
Stem cells:
Definition
"Unmade" cells that can be taken from different body parts/embryos,can also be planted in weak body parts, "read" the existing cells, and copy them
Term
Where can stem cells be found?
Definition
Umbilical cords
Bone marrow
Embryos
Term
What chromosome transfers from father to son?
Definition
Y chromosome
Term
What carries the mothers DNA?
Definition
- Egg
Term
Where in the cell is the DNA located?
Definition
Mitochondrial
Term
What can you look at to check the family heritage on your mothers side?
Definition
Mitochondrial DNA
Term
What can you look at to check your family tree on your fathers side?
Definition
Your father's family tree traced through the fathers
Term
What does ESC stand for?
Definition
Embryonic Stem Cells
Term
Deontological Bioethics:
Definition
Black or white. No gray area.
Term
Utilitarian Bioethics:
Definition
Done for the greater good
Term
Relationism:
Definition
Belief asserting the existence of relations as entities (its existence)
Term
Science is composed of:
Definition
- Empiric Data
- Rational Thinking
- Experimentation and testing of hypothesis
Term
Fabrication:
Definition
Making up scientific data
Term
Unconscious bias:
Definition
Fraudulent data or lying about experiment data and results
Term
Abiogenisis:
Definition
The theory that living organisms can come out of nonliving matter
Term
Where did the water on Earth today come from?
Definition
Comets hitting the earth millions of years ago
Term
If a nonliving DNA molecule is injected into a living being what happens?
Definition
The nonliving DNA molecule will replicate the living DNA and become alive again
Term
What does Gene Therapy do?
Definition
Takes a deformed gene and fixes it
Term
What do Stem Cells do?
Definition
Repair tissue
Term
Describe the life cycle of a fly
Definition
Starts as EGG, becomes LARVAE, then a MAGGOT, which feeds on decaying organisms and grows into fly
Term
What was the life span in the 1800s?
Definition
Roughly 44 years
Term
Spontaneous Generation:
Definition
The supposed production of living organisms from nonliving matter
Term
Was Pasteur for or against spontaneous generation?
Definition
Against
Term
Nucleic Acids / ?
Definition
Amino Acids
Term
What are amino acids composed of?
Definition
Fats, lipids, carbs, proteins
Term
DNA / ?
Definition
RNA
Term
Was Pouchet for or against spontaneous generation?
Definition
For spontaneous generation
Term
Did Pouchet's test prove Spontaneous Generation?
Definition
No
Term
What do Botalism molecules create?
Definition
A toxin that is quick and fatal to human beings.
Term
Where can a human receive Botalism molecules?
Definition
Improperly presesrved cans and jars
Term
What do Botalism molecules do in high quantities?
Definition
Paralyze organs, muscles, and tissues until you're dead
Term
What are small doses of Botalism molecules also known as?
Definition
Botox
Term
Is a valid argument always true?
Definition
No
Term
Examples of Spontaneous Generation:
Definition
Maggots growing on meat
Mold growing in damp, warm areas
Term
In the Pasteur/Pouchet experiment, what was the control group?
Definition
The uncovered meat that grew the maggots
Term
In the Pasteur/Pouchet experiment, what was the variable group?
Definition
The covered meat
Term
Observation leads to?
Definition
Conclusion by inductive reasoning
Term
Hypothesis leads to?
Definition
Deduction
Term
Experiment Hypothesis standard set-up:
Definition
If ___ is done, then ___ will happen because ___
Term
If my hypothesis is correct,:
Definition
I cannot have a false prediction
Term
If my hypothesis is wrong,:
Definition
I can have a true prediction
Term
Example of hypothesis:
Definition
People 65 or older have a high percentage of diabetes. Is aging the cause of diabetes? (No)
Term
Any test subjects for a clinical trials must:
Definition
give informed consent before undergoing testing
Term
What happened in Tuskeegee Alabama?
Definition
Black men in Tuskeegee with syphilis were tested on for a cure but were never informed of a cure when penicillin was discovered
Term
Syphilis
Definition
STD, enters the body during sexual contact
Term
What does Syphilis cause?
Definition
Dementia, blindness, nerve damage, paralysis, a womans ability to get pregnant, and can infect a child during labor
Term
What year was penicillin discovered?
Definition
1943
Term
Penicillin cures syphilis how?
Definition
Kills the bacteria in the genital area but cannot reverse any physical damage done to the body
Term
What happened with the research study in Guatemala?
Definition
Scientists hired prostitutes with syphilis and sent them to men to infect them with syphilis to study them without consent
Term
When approached about a clinical trial, you must be informed of what?
Definition
- Risks/side effects
- What treatment plan/drug does
- Chances (if done on people/animals before)
- Name/Formula
- Summary of results so far
- How drug or treatment plan is given
- How often it must be taken
Term
Trial host must:
Definition
Answer any and all questions asked
Term
Petri dishes:
Definition
In vitro "cells"
Term
Phase I studies:
Definition
Consists of 25-50 people
Focuses on side effects
Term
Phase II studies
Definition
Effective dosage
Consists of 50-200 people
Term
Phase III studies
Definition
Typically divided between control group and drug group
Consists of around 1000 participants
Term
Single-Blinded Study:
Definition
Patient doesn't know what could happen
Term
Double-Blinded Study:
Definition
The nurses, Doctor, and Patient don't know what could happen
Term
Paradigm:
Definition
a pattern that serves as a model or an example
Term
Anomaly
Definition
Something that does what isn't standard, normal, or expected
Term
Panspernia
Definition
Theory that the first living cell came from outer space because the Earth came from outer space
Term
Biogenesis
Definition
Living beings come from living beings
Term
Example of Biogenesis
Definition
Humans will come from humans, rats will come from rats, etc
Term
Null hypothesis:
Definition
Theory that there is no significant difference between specified populations, any observed difference being due to sampling or experimental error
Term
False Hypothesis:
Definition
Incorrect hypothesis.
Term
Conscious bias:
Definition
Purposely lying about experiment, results, data, and other aspects
Term
What happened at the Bowery in the Lower East Side in 1948?
Definition
13 men were found dead with blue skin
Term
What were some theories behind why the dead men had blue skin?
Definition
- Lack of Oxygen to the blood
- Air pollution
- Chronic Obstructive Pulminary Disease
- Vitamin deficiency
- Suffocation
- Work-related Toxic chemicals or working conditions
Term
How did all 13 men acquire the blue tinged skin?
Definition
They all ate oatmeal at a diner that morning before work and used the salt shaker. Rather than salt, the immigrant that filled the bag of salt the diner used with Potassium nitrate, which is lethal in certain doses.
Term
What is Potassium nitrate used for?
Definition
Brining corn beef, cheaper alternative
Term
What are some examples of genetically modified food?
Definition
Soybeans
Corn products
Canola
Cotton seed oil products
Term
What are genetically modified foods engineered to do?
Definition
- Grow faster
- Decay or spoil slower
- Look better when packaged
- Withstand the weather in the area it's grown in
- Withstand hungry animals, homeless, etc
- Withstand antibiotics or pesticides in the soil
Term
What happens during genetic modification?
Definition
One or more genes are added to a plant's genome using genetic engineering techniques, after a plant is tested in the lab for its desired qualities
Term
What do they do with the newly genetically modified plant?
Definition
Gather the seeds and plant them in their field-test
Term
What happens if the field tests of the genetically modified plants are successful
Definition
The plants will be packaged and marketed
Term
What was the original idea of infectious disease?
Definition
Being anywhere near an infected person or thing would give you the disease
Term
Are infection and contagion the same thing?
Definition
No
Term
Definition of Infectious?:
Definition
An organism that can cause disease
Term
Examples of Infectious agents?
Definition
- Bacteria
- Fungi
- Viruses
- Protozoans
- Prions
Term
Definition of Contagious?
Definition
Spread from person to person by direct or indirect contact.
Term
How can contagious diseases be spread?
Definition
- The air
- Body fluids
- Sexual contact
- Touch
Term
Some examples of the germiest things in your home that you touch or do are:
Definition
- Bathrooms
- Cell phones
- Door knobs
- Sink and soap nozzles
- Talking
- Coughing/Sneezing without covering up
- Food (can be spoiled or undercooked)
- Water (if old or untreated)
Term
Where does vacca come from?
Definition
Vacca means "cow" in Spanish.
Term
Where did the first vaccine come from?
Definition
Cows that kept their milkmaids free of smallpox
Term
What is smallpox?
Definition
A disease that left huge, pus-filled, gaping holes in every organ of the body, internal and external.
Term
How many people that were affected by smallpox die from it?
Definition
30%
Term
How many people affected by malignant smallpox die from it?
Definition
over 85%
Term
What happened to the 10% of those affected by smallpox that survived it?
Definition
They went blind, had large scars all over their body and organs from the pox
Term
Why didn't smallpox affect the milkmaids?
Definition
The milkmaids all were infected with cow pox, which can infect humans but will not make them sick. It also makes them immune to smallpox
Term
What did Jenner do in 1796?
Definition
Scratched an 8 year old boys hand and infected him with cow pox
Term
What was the "original" way to vaccinate people?
Definition
Scratch their arm or hand until it bled and then put the vaccine into their blood through the wound
Term
Was the boy infected by smallpox when he went home?
Definition
No
Term
During the height of the smallpox epidemic, how many people a year died from it?
Definition
400,000
Term
How many other people did Jenner test his theory on and were they all successful?
Definition
22 and yes
Term
What became of smallpox after this discovery?
Definition
The World Health Organization (WHO) would go to areas stricken by the disease and vaccinate the healthy so they would not get sick. Those who were infected would either die with the disease or survive with the side effects
Term
When did the USA stop vaccinating their citizens for smallpox?
Definition
The 1960s
Term
When did the World Health Organization declare smallpox eradicated?
Definition
The 1970s
Term
Some examples of viral infections with vaccines?
Definition
- Whooping cough/Pertussis
- Tetanus
- Smallpox
- Flu
- Chicken Pox
- Hepatitis C
- Polio
Term
What happened to those that were given the live vaccine for polio?
Definition
The vaccine actually gave some people polio
Term
What were hospitals like back before hygiene was common knowledge?
Definition
A place for you to go and die
Term
What would happen to women that went to hospitals to give birth?
Definition
The mother would die from the dirtiness of the area she was in and the people handling her and her child, and the baby would die sometimes as well
Term
What was the common sense that struck people that saved many lives in hospitals?
Definition
Routine hand and clothes washing prevented a lot of deaths in their patients
Term
What was the name of the fatal virus in Outbreak?
Definition
the Motaba Virus
Term
What virus was the Motaba Virus in the movie "Outbreak" based on in real life?
Definition
the Ebola virus
Term
What were the symptoms of Motaba in the movie "Outbreak"?
Definition
- Liquefies organs
- Makes pustules appear on the skin
- The pustules pop and blood and pus pours out
- 100% mortality rate
- Death in 2-3 days
Term
What was the name of the city in California that was infected with the Motaba virus?
Definition
Cedar Creek, CA
Term
What were the intentions of General McClintok and General Ford with the Motaba virus?
Definition
To keep the disease hidden from the general public to use it as biological warfare
Term
How did the virus in the movie Contagion spread?
Definition
1) A bulldozer knocks down a tree with a bats nest in it
2) The bat carrying the virus flies away and lands on a banana plant and eats a banana chunk
3) The bat flies away and lands on a water pipe over a pig pen eating the banana
4) The bat drops a chunk of banana into the pen and a piglet eats the banana chunk, infecting itself and forming a new strain of the virus
5) Chinese chefs collect all of the piglets and butcher them
6) The chef that butchers the diseased piglet doesn't wash his hands before shaking hands with Beth, who brings the disease back to her hometown
Term
What is "Patient Zero"?
Definition
The first known victim of any virus or contagion
Term
What is the name of the virus in the movie "Contagion"?
Definition
Meningoencephalitis Virus One, or MEV-1
Term
What does SARS stand for?
Definition
Severe Acute Respiratory Syndrome
Term
When and where did SARS first appear?
Definition
February 2003 in Asia
Term
Who is Typhoid Mary?
Definition
Host of typhoid fever whose stubbornness infected many people with typhoid
Term
What was Typhoid Mary's occupation in which she spread Typhoid, where did she primarily work and during what decades?
Definition
She was a cook in NYC in the late 1880s-1910's
Term
How was Typhoid Mary spreading the disease?
Definition
She wasn't washing her hands as she cooked and typhoid was being spread through her food
Term
When the government warned her to stop cooking food, what did she do instead?
Definition
Change her name and go to work for private families or restaurants in the Long Island/Westchester county area
Term
When she was caught for the last time after typhoid broke out in her newest place of employment, what did the government do?
Definition
Put her in a quarantine until her death
Term
What is a Quarantine?
Definition
A state of isolation where animals or people exposed to infectious or contagious disease are placed
Term
What is an Anti-Serum?
Definition
The liquid in the vaccine that acts against the virus when the body is already infected with it
Term
What does the anti-serum create?
Definition
It creates the proteins that your body would make if it wasn't already infected by the virus
Term
How long does it take anti-bodies to create in the body?
Definition
7-10 days
Term
What do vaccines prevent?
Definition
Vaccines prevent the virus from ever infecting the body
Term
Is the virus in vaccines alive?
Definition
If it is alive, it is weakened. Most of the time it is dead
Term
What is a carrier?
Definition
The host animal or human of a virus
Term
How can Mad Cows Disease be received?
Definition
If the victim eats infected meat
Term
How does Mad Cows Disease cause dementia?
Definition
The strand of protein in the infected meat attacks the brain
Term
Run of the mill influenza will transfer from:
Definition
People to people
Term
Bird influenza travels from ___ to ___ and then:
Definition
Travels from bird to bird and then mutates to enter and infect humans
Term
Flu is what kind of virus?
Definition
RNA
Term
What are the spikes on an RNA virus made up of?
Definition
Proteins
Term
How many people died on influenza in 1918?
Definition
100-150 million
Term
Do all illness carriers display symptoms?
Definition
No
Term
What is cilia?
Definition
short, almost microscopic hair found on the body that prevents germs, viruses, and bacteria from entering the body
Term
Some examples of cilia?
Definition
Eyelashes, ear hair, nose hair
Term
What does healthy skin act as?
Definition
A strong barrier to the outside world
Term
What do sweat glands do?
Definition
Make fatty acids that releases unwanted shit from the body
Term
What does saliva contain?
Definition
Enzymes and lysozymes
Term
The stomach has a:
Definition
low ph count
Term
What does WBC stand for?
Definition
White Blood Cells
Term
What does it mean to have Innate WBCs?
Definition
It means you're naturally born with them
Term
What does CBC stand for?
Definition
Complete Blood Count
Term
What are the different parts to blood?
Definition
Red Blood Cells
White Blood Cells
Platelets
Term
What does it mean to not have enough blood cells?
Definition
It means you have anemia
Term
What does CBC with differentials tell a doctor?
Definition
What kind of white blood cells you have
Term
In order to receive stem cells, what must they match?
Definition
Your genetics
Term
Adaptive WBCs are?
Definition
Learned
Term
What are the components that make up lymphocytes?
Definition
T cells
B cells
Term
Who discovered Penicillin?
Definition
Alexander Fleming
Term
What is Penicillin?
Definition
An antibiotic that fights off bacteria
Term
Who cannot make antibiotics naturally?
Definition
Mammals
Term
What makes an antibiotic?
Definition
Mold and Fungi
Term
What is inside of the Staph?
Definition
A slant with nutrient media and agar
Term
What is inside of the Petri Dish?
Definition
A form of nutrient media growing with agar inside
Term
What German scientist worked with bacteria?
Definition
Robert Koch
Term
What did Robert Koch discover?
Definition
That bacteria must be given nutrient media to develop and work
Term
What is the purpose of the agar in these experiments?
Definition
To provide a solid surface for the bacteria to grow
Term
How did Fleming discover Penicillin?
Definition
He looked into one of his petri dish experiments and realized that the bacteria around the mold had died
Term
What percentage of antibiotics are given to animals?
Definition
80%
Term
How do humans receive a majority of our antibiotics?
Definition
By eating meat, meat products, or dairy products
Term
How does the body react to Penicillin if allergic?
Definition
1) The Penicillin attaches to red blood cells
2) The body sees this as a foreign protein and attack
Term
How could health officials in the 18-1900's tell if a family was ill even if they weren't showing symptoms?
Definition
If the child was ill and showing symptoms
Term
What did Joseph Lister discover that seems like common sense now?
Definition
Washing your hands before doing anything in a hospital would reduce the mortality rate
Term
What happens if local infections such as an infected toenail or a pimple get into your blood stream?
Definition
It will travel right to your organs and can infect them
Term
What makes up immune system?
Definition
Natural and Learned parts of the immune system
Term
One of the children Pasteur originally worked on worked in Pasteur's institute years later and wouldn't allow the Germans in so he committed suicide, to distract the German so the French could defeat them. What disease did he have?
Definition
Rabies
Term
Who was the first preson to link pure bacteria with an illness?
Definition
Robert Koch
Term
Why were immigrants at Ellis Island afraid to be found sick?
Definition
They would be sent back to their home countries if found sick
Term
What insurance company was the first to help hospitals pay for sick patients to become well?
Definition
Metlife Insurance
Term
What did Metlife pay for in these hospitals and why did they do this?
Definition
Metlife paid for preventive medicine, doctors appointments, vaccines, and surgeries. They did this because it would save them more money doing this than paying death benefits to families of the deceased
Term
Umbilical cord blood:
Definition
Blood that remains in the umbilical cord and placenta after childbirth
Term
Embryonic stem cells:
Definition
pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage embryo.
Term
In vitro:
Definition
Taking place in a test tube, culture dish, or elsewhere outside a living organism.
Term
In Vitro Fertilization:
Definition
a process by which egg cells are fertilised by sperm outside the womb, in vitro
Term
In Vivo:
Definition
Taking place in a living organism
Term
Active Immunity:
Definition
The immunity that results from the production of antibodies in response to an antigen.
Term
Adaptive Immunity:
Definition
composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth.
Term
An adaptive immune system is also known as:
Definition
Acquired immune system
Specific immune system
Term
What does AIDS stand for?
Definition
Acquired Immune Deficiency Syndrome
Term
AIDS is:
Definition
The final stage of HIV disease, which causes severe damage to the immune system.
Term
Allergies are:
Definition
A damaging immune response by the body to a substance, esp. pollen, fur, a particular food, or dust, to which it has become hypersensitive.
Term
Antibodies:
Definition
A blood protein produced in response to and counteracting a specific antigen.
Term
Antigens:
Definition
A toxin or other foreign substance that induces an immune response in the body, esp. the production of antibodies.
Term
Autoimmunity:
Definition
production of antibodies against the tissues of your own body; produces autoimmune disease or hypersensitivity reactions.
Term
B Lymphocytes are:
Definition
a lymphocyte derived from bone marrow that provides humoral immunity
Term
What do B Lymphocytes do?
Definition
recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigens
Term
Blood plasma:
Definition
(the colorless watery fluid of the blood and lymph that contains no cells, but in which the blood cells (erythrocytes, leukocytes, and thrombocytes) are suspended
Term
Bone marrow:
Definition
the fatty network of connective tissue that fills the cavities of bones.
Term
Chemotaxis:
Definition
the movement of a microorganism or cell in response to a chemical stimulus
Term
Contact Hypersensitivity occurs when:
Definition
an antigen interacts with antigen-specific lymphocytes that release inflammatory and toxic substances, which attract other white blood cells and results in tissue injury.
Term
Cytotoxicity:
Definition
the degree to which something is toxic to living cells
Term
Delayed Type Hypersensitivity:
Definition
The reaction is delayed, often 2-3 days
Term
Granulocytes:
Definition
A white blood cell with secretory granules in its cytoplasm
Term
Examples of secretory granules in a white blood cell?
Definition
an eosinophil or a basophil.
Term
Helper cells are:
Definition
A T cell that influences or controls the differentiation or activity of other cells of the immune system.
Term
HLA stands for:
Definition
the Human Leukocyte Antigen system
Term
HLA Antigens:
Definition
A complex family of genetically inherited proteins, which are found on the surface of cells throughout the body.
Term
What are HLA antigens used to do?
Definition
They determine the "match" between patient and potential donor in bone marrow transplantation
Term
What is the HLA Class I(A, B, C) responsible for?
Definition
Present peptides from inside the cell
Term
What is the HLA Class II (DR, DP, DQ) responsible for?
Definition
Present antigens from outside of the cell to T-lymphocytes
Term
Hypersensitivity:
Definition
pathological sensitivity.
Term
Immune complexes are formed from:
Definition
the integral binding of an antibody to a soluble antigen
Term
What is Immune Deficiency?
Definition
state in which the immune system's ability to fight infectious disease is compromised
Term
What is Immune Globulin?
Definition
a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response
Term
What is Immune Therapy?
Definition
The prevention or treatment of disease with substances that stimulate the immune response.
Term
Immunization:
Definition
the act of making immune (especially by inoculation).
Term
Incidence:
Definition
The occurrence, rate, or frequency of a disease, crime, or something else undesirable
Term
Incubation period:
Definition
The period between exposure to an infection and the appearance of the first symptoms
Term
Inflammation:
Definition
A localized physical condition in which part of the body becomes reddened, swollen, hot, and often painful
Term
What is Innate Immunity?
Definition
natural immunity to disease that occurs as part of an individual's natural biologic makeup
Term
What is Kaposi's sarcoma?
Definition
a cancerous tumor of the connective tissue, and is often associated with AIDS
Term
What are Killer T Cells?
Definition
A T cell with a particular immune specificity and an endogenously produced receptor for antigen, capable of specifically killing its target cell after attachment to the target cell by this receptor
Term
Leukocytes:
Definition
A colorless cell that circulates in the blood and body fluids and is involved in counteracting foreign substances and disease
Term
Lymph Nodes:
Definition
Each of a number of small swellings in the lymphatic system where lymph is filtered and lymphocytes are formed.
Term
Lymphocytes:
Definition
A form of small leukocyte (white blood cell) with a single round nucleus, occurring in the lymphatic system.
Term
What is a Lysozyme?
Definition
An enzyme that catalyzes the destruction of the cell walls of certain bacteria, occurring notably in tears and egg white.
Term
Macrophage:
Definition
A large phagocytic cell found in stationary form in the tissues or as a mobile white blood cell, notably occuring at sites of infection.
Term
Malnutrition:
Definition
Lack of proper nutrition
Term
Memory Lymphocytes:
Definition
small agranulocytic leukocytes originating from fetal stem cells and developing in the bone marrow that don't secrete antibodies but when exposed to the specific antigen, develop into antibody-secreting plasma cells
Term
What does MHC stand for?
Definition
Major histocompatibility complex
Term
What are MHC Antigens?
Definition
the chromosomal region containing genes that control the histocompatibility antigens
Term
Monocyte:
Definition
A large phagocytic white blood cell with a simple oval nucleus and clear, grayish cytoplasm.
Term
Mucous membranes:
Definition
An epithelial tissue that secretes mucus and that lines many body cavities and tubular organs including the gut and respiratory passages.
Term
Negative Selection:
Definition
The selective removal of alleles that are deleterious
Term
Natural Killer (NK) Cells:
Definition
A lymphocyte able to bind to certain tumor cells and virus-infected cells without the stimulation of antigens and kill them.
Term
Opportunistic Infections:
Definition
any infection caused by a microorganism that does not normally cause disease in humans
Term
Passive Immunity:
Definition
The short-term immunity that results from the introduction of antibodies from another person or animal.
Term
What is a Pathogen?
Definition
A bacterium, virus, or other microorganism that can cause disease
Term
Phagocytes:
Definition
A type of cell within the body capable of engulfing and absorbing bacteria and other small cells and particles.
Term
Phagocytosis:
Definition
The ingestion of bacteria or other material by phagocytes and ameboid protozoans
Term
Plasma Cells:
Definition
A fully differentiated B cell that produces a single type of antibody
Term
Primary Immunodeficiencies are:
Definition
disorders in which part of the body's immune system is missing or does not function properly
Term
What are receptors?
Definition
An organ or cell able to respond to light, heat, or other external stimulus and transmit a signal to a sensory nerve
Term
Red Blood Cells:
Definition
a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues
Term
What does SCIDS stand for?
Definition
Severe Combined Immuno-Deficiency Syndrome
Term
What is SCIDS?
Definition
a congenital disease affecting T cells that can result from a mutation in any one of several different genes
Term
What are Secondary Immunodeficiencies?
Definition
state in which the immune system's ability to fight infectious disease is compromised or entirely absent
Term
What is a Spleen?
Definition
An abdominal organ involved in the production and removal of blood cells in most vertebrates and forming part of the immune system.
Term
What are Sweat Glands?
Definition
A small gland that secretes sweat, situated in the dermis of the skin
Term
What is a Thymus?
Definition
A lymphoid organ situated in the neck of vertebrates that produces T cells for the immune system
Term
Tolerance is:
Definition
The capacity to endure continued subjection to something, such as a drug, transplant, antigen, or environmental conditions
Term
Toxins:
Definition
An antigenic poison or venom of plant or animal origin, esp. one produced by or derived from microorganisms and causing disease when present at low concentration in the body
Term
Transplantation:
Definition
An operation moving an organ from one organism (the donor) to another (the recipient)
Term
Vaccination:
Definition
A biological preparation that improves immunity to a particular disease
Term
What is Vaccinia?
Definition
Cowpox, or the virus that causes it
Term
What are Vitamins?
Definition
Any of a group of organic compounds that are essential for normal growth and nutrition and are required in small quantities in the diet
Term
What are White Blood Cells?
Definition
Blood cells that engulf and digest bacteria and fungi
Term
What is Aerosol?
Definition
A substance enclosed under pressure and able to be released as a fine spray, typically by means of a propellant gas
Term
Airborne:
Definition
Transported by air
Term
What are Antibiotics?
Definition
A medicine (such as penicillin or its derivatives) that inhibits the growth of or destroys microorganisms.
Term
What is Antibiotic Resistance?
Definition
a type of drug resistance where a microorganism is able to survive exposure to an antibiotic
Term
What is an Antibody?
Definition
A blood protein produced in response to and counteracting a specific antigen
Term
Antiserum:
Definition
A blood serum containing antibodies against specific antigens, injected to treat or protect against specific diseases
Term
What is an Antitoxin?
Definition
An antibody that counteracts a toxin, or an antidote
Term
Asymptomatic:
Definition
Showing no symptoms
Term
What is Avian influenza?
Definition
flu infection in birds. The virus that causes the bird infectin can change (mutate) to infect humans
Term
Bacteria:
Definition
A member of a large group of unicellular microorganisms lacking organelles and an organized nucleus, including some that can cause disease.
Term
What is a Blood bank?
Definition
A place where supplies of blood or plasma for transfusion are stored
Term
What is supply contamination?
Definition
Bacterial contamination of blood components
Term
What are body fluids?
Definition
the liquid parts of the body
Term
What is the Bubonic Plague?
Definition
The commonest form of plague in humans, characterized by fever, delirium, and the formation of buboes
Term
What is Bush meat?
Definition
Wildlife not traditionally considered edible that is hunted and used for food, usually illegally
Term
What is the definition of a Carrier?:
Definition
A person or an animal that shows no symptoms of a disease but harbors the infectious agent of that disease and is capable of transmitting it to others
Term
What is the CDC Center for Disease Control and Prevention?
Definition
Focuses national attention on developing and applying disease prevention and control (especially infectious diseases, foodborne pathogens and other microbial infections), environmental health, occupational safety and health, health promotion, injury prevention and education activities designed to improve the health of the people of the United States
Term
What is Cholera?
Definition
an infection of the small intestine that causes a large amount of watery diarrhea.
Term
Communicable disease:
Definition
a disease that can be communicated from one person to another
Term
Contagious disease:
Definition
any disease easily transmitted by contact
Term
Contaminated:
Definition
To make something impure by exposure to or addition of a poisonous or polluting substance.
Term
What is Dengue fever?
Definition
A debilitating viral disease of the tropics, transmitted by mosquitoes, and causing sudden fever and acute pains in the joints.
Term
What is DPT (Diphtheria, Pertussis, Tetanus)?
Definition
A vaccine that is combined to fight all of these diseases and is typically given to children
Term
Emerging Disease:
Definition
A disease that has either appeared in a specific area for the first time, or has recently evolved from another disease
Term
Endemic:
Definition
Regularly found among particular people or in a certain area
Term
Epidemic:
Definition
A widespread occurrence of an infectious disease in a community at a particular time: "a flu epidemic"
Term
Epidemiology:
Definition
The branch of medicine that deals with the incidence, distribution, and control of diseases
Term
What is escherchia coli?
Definition
Also known as E. Coli, it's a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms.
Term
What is Flesh-eating bacteria?
Definition
a rare infection of the deeper layers of skin and subcutaneous tissues, easily spreading across the fascial plane within the subcutaneous tissue.
Term
Definition of Foodborne:
Definition
any illness resulting from the consumption of contaminated food
Term
What is Hand to Mouth contact?
Definition
touching something that may be contaminated with bacteria with your hand and then touching your mouth
Term
What is Hemorrhagic fever?
Definition
a group of illnesses caused by a viral infection (usually restricted to a specific geographic area); fever and gastrointestinal symptoms are followed by capillary hemorrhage
Term
What is Helicobacter?
Definition
a Gram-negative, microaerophilic bacterium found in the stomach
Term
What is Hepatitis A?
Definition
Inflammation of the liver from the Hepatitis A virus
Term
What is Hepatitis B?
Definition
A severe form of viral hepatitis transmitted in infected blood
Term
What is Hepatitis C?
Definition
A form of viral hepatitis transmitted in infected blood, causing chronic liver disease
Term
What is herd immunity?
Definition
General immunity to a pathogen in a population based on the acquired immunity to it by a high proportion of members over time
Term
What is a Host?
Definition
an organism that originally harbors or nourishes a virus or bacteria
Term
What is Immune Globulin?
Definition
Any of a class of proteins present in the serum and cells of the immune system, that function as antibodies.
Term
What is Immune Memory?
Definition
The increased response of the immune system to an antigen that had been encountered before. This is the basis of vaccination.
Term
What is an Incubation Period?
Definition
The period between exposure to an infection and the appearance of the first symptoms.
Term
Defintion of Infection:
Definition
An infectious disease: "a bacterial infection".
Term
Infectious definition:
Definition
Liable to spread infection
Term
What is Infectious Disease?
Definition
a disease transmitted only by a specific kind of contact
Term
What is Lyme disease?
Definition
A bacterial infection spread through the bite of the blacklegged tick.
Term
What is Mad Cow Disease?
Definition
A degenerative neurologic disease of cattle, thought to be caused by infection-causing agents called prions, in which brain tissues deteriorate and take on a spongy appearance, resulting in abnormal behaviors and loss of muscle control
Term
What is Malaria?
Definition
An intermittent and remittent fever caused by a protozoan parasite that invades the red blood cells
Term
What are Measles?
Definition
An infectious viral disease causing fever and a red rash on the skin.
Term
What are Microbes?
Definition
A microorganism, esp. a bacterium causing disease or fermentation
Term
What does MMR stand for?
Definition
Measles, Mumps ,and Rubella
Term
What is MMR?
Definition
A vaccination given to small children to prevent measles, mumps, and rubella
Term
What is MRSA?
Definition
Methicillin-resistant Staphylococcus aureus, a bacterium with antibiotic resistance.
Term
What is Multi-drug resistance?
Definition
The ability to withstand many antimicrobial drugs
Term
What is Normal Flora?
Definition
The human flora is the assemblage of microorganisms that reside on the surface and in deep layers of skin, in the saliva and oral mucosa, and in the gastrointestinal tracts
Term
Pandemic:
Definition
An outbreak of a disease that is prevalent over a whole country or the world
Term
Parasites:
Definition
An organism that lives in or on another organism (its host) and benefits by deriving nutrients at the host's expense.
Term
What are Passive Antibodies?
Definition
A type of immunity acquired by the transfer of antibody from one individual to another, such as from mother to offspring.
Term
What is the importance of Plum Island?
Definition
It hosts an animal disease control center
Term
Prevalence:
Definition
the quality of prevailing generally; being widespread
Term
What are Prions?
Definition
A protein particle that is believed to be the cause of brain diseases such as BSE, scrapie, and Creutzfeldt–Jakob disease
Term
What is a Protist?
Definition
Protists are a diverse group of eukaryotic microorganisms
Term
Protozoan:
Definition
any of diverse minute acellular or unicellular organisms usually nonphotosynthetic.
Term
What is a Puerperal sepsis?
Definition
An infection of the endometrium after childbirth or an abortion
Term
What is Pus?
Definition
A thick yellowish or greenish opaque liquid produced in infected tissue, consisting of dead white blood cells and bacteria with tissue debris and serum
Term
What are Rabies?
Definition
deadly viral infection that is mainly spread by infected animals through saliva and bites breaking through the first barrier of skin
Term
What is the Disease Reservoir?
Definition
the long-term host of the pathogen of an infectious disease
Term
What is a Retrovirus?
Definition
Any RNA virus that inserts a DNA copy of its genome into the host cell in order to replicate such as HIV
Term
What is the SARS virus?
Definition
the virus that causes severe acute respiratory syndrome
Term
What is Sepsis?
Definition
The presence in tissues of harmful bacteria and their toxins, typically through infection of a wound.
Term
Syphilis:
Definition
A chronic bacterial disease that is contracted chiefly by infection during sexual intercourse, but also congenitally by infection of a developing fetus
Term
What does it mean for a disease to be tick-borne?
Definition
The disease is carried or transmitted by ticks
Term
Definition of toxin:
Definition
An antigenic poison or venom of plant or animal origin, esp. one produced by or derived from microorganisms and causing disease when present at low concentration in the body
Term
Transmissible:
Definition
catching: (of disease) capable of being transmitted by infection
Term
Transmission:
Definition
The action or process of transmitting something or the state of being transmitted
Term
What is Tuberculosis?
Definition
a contagious bacterial infection that involves the lungs. It may spread to other organs.
Term
What is a Vector?
Definition
A quantity having direction as well as magnitude, esp. as determining the position of one point in space relative to another.
Term
What are Viruses?
Definition
a small infectious agent that can replicate only inside the living cells of an organism
Term
What is the West Nile Encephalitis Virus?
Definition
the flavivirus that causes West Nile encephalitis.
Term
What is the World Health Organization (WHO)?
Definition
An agency of the United Nations, established in 1948 to promote health and control communicable diseases.
Term
What is Yellow Fever?
Definition
A tropical viral disease affecting the liver and kidneys, causing fever and jaundice and often fatal. It is transmitted by mosquitoes.
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