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S3 Ross Pharm General Anesthetics
Azim
10
Pharmacology
Professional
11/23/2009

Additional Pharmacology Flashcards

 


 

Cards

Term
Define the 4 stages of General Anesthesia
Definition

1. Analgesia

2. Stage of excitement: irregular respiration

3. Stage of surgical anesthesia: normal respiration

4. Stage of medullary depression: no respiration

Term
What does a higher MAC translate to in terms of potency?
Definition
Higher MAC means less potency.
Term
What is the MOA of most inhailed anesthetics?
Definition
Opens the GABAa regulated Ca channel.
Term
This general anesthetic has a higher solubilty in fat than blood.
Definition
Halothane
Term
What are two important adverse effects of Halothan?
Definition

Fulminant hepatic necrosis

Malignant hyperthermia (+ succinylcholine)

Term
So it turns out hiring an anethesiology off of craigs list was a bad idea. Your patient has just started to experience seizures. What general anesthetic do you think caused this?
Definition
Probably Isoflurane. Recall that this drug
Term
This drug should not be used in Automatic Anethesia Machine Despenser Rhingies if the AAMDT uses dissicated CO2 absorbant.
Definition
Sevoflurane. It may cause airway burns
Term
Halothane can cause Malignant Hyperthermia. What is the treatment for this and what is its MOA?
Definition

Dantrolene. It blocks calcium release from the sarcoplasmic reticulum.

 

Recall that Malignant Hyperthermia presents with hyperthermia, tachycardia, metabolic acidosis, hypercalcemia, muscle contraction and myoglobinura.

Term
An anethetic that has a 100% MAC and can cause diffusion hypoxia.
Definition

Nitrous Oxide

 

The diffusion hypoxia occurs when NO is quickly removed from the patient's ventilator and NO from the plasma rapidly diffuses into the alveoli and replaces oxygen.

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