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S1- Mini 3
n/a
84
Medical
Professional
03/28/2011

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Term
Sensitivity formula
Definition
a/(a+c)
Term
Specificity Formula
Definition
d/(b+d)
Term
Positive Predictive Value
Definition
a/(a+b)
Term
Negative Predictive Value
Definition
d/(c+d)
Term
First Aortic Arch Forms
Definition
Maxillary A.
Term
2nd Aortic Arch
Definition
Stapedal A.
Term
Third Aortic Arch forms
Definition
Right and left common carotids
Term
Fourth Aortic Arch
Definition
ASSYMETRIC
Left-Arch of Aorta
Right-Right Subclavian A.(proximal seg)
Term
6th Aortic Arch forms
Definition
ASSYMETRIC--Pulmonary Arch
Left-Ductus Arteriosus & some L Pulm A.
Right-Right Pulm A.
Term
Inf. Vena Cava--Hepatic segment
Definition
right Vitelline vein
Term
IVC--Renal Segment
Definition
Right Subcardinal Vein
Term
IVC--Postrenal/Sacrocardinal Seg
Definition
Right Sacrocardinal V.
Term
SVC forms from
Definition
Right common cardinal v. and right ant cardinal v.
Term
Left brachiocephalic vein from
Definition
Left and right anterior cardinal veins
Term
Formation of Aorta and Pulm Trunk from
Definition
Truncus Arteriousus
Term
Formation of Aorta and Pulm Trunk from
Definition
Truncus Arteriousus
Term
Formation of Ventricles
Definition
Smooth Portions-Caudal portion of bulbis cordis
Trabeculated-Primitive ventricle
Term
Formation of atrium
Definition
Trabeculated part of Atria- Primitive Atria
Smooth R Atrium-Sinus Venosus
Term
citrate is intermediate of
Definition
FA synthesis
Term
Alpha Ketoglutarate int of
Definition
AA (GABA) and NT syn
Term
Succynl CoA int of
Definition
Heme syn
Term
L-Malate int of
Definition
Gluconeogenesis
Term
oxaloactate int of
Definition
AA syn (Asp)
Term
Alveolar PO2 (PAO2)
Definition
PAO2= PIO2-PACO2/R
Term
Alveloar PCo2 (PACO2)
Definition
PACO2= (V.CO2/V.A)*863
Term
Avg PACO2
Definition
40 mmHg
Term
Tension Pneumothorax
Definition
pushes mediastinum to opposite side of chest
Term
3 famial hypertrophic cardiomyopathy proteins are
Definition
beta-myosin heavy chain
cardiac tropinin t
cardiac myosin-binding protein c
Term
DCM from
Definition
disease of cytoskeleton
Term
Pompe disease
Definition
recessive 1,4 glucosidase
Term
danon disease
Definition
Lamp2 x linked
Term
fabry
Definition
galactosidase a
x linked
Term
PRKAG2
Definition
AMP Kinase
Term
Restrictive Cardiomyopathy
Definition
Decreased vol of both ventricles
Cardiac troponin I
Term
Arrthmyogenic right ventricular cardiomyopathy ARVC
Definition
Predominates right ventricle and replacement with fatty or fibrofatty tissue.
-Disease of desmosome
Term
Most common cause of channelopathy in Cardiac
Definition
K+
Term
Long QT Syndrome
Definition
Auto-Dom
60% prob with k Channel
Term
Short QT
Definition
SQTS repolarization is hastened by enhanced outward current
Term
Brugada Syndrome
Definition
ST elevation in right precordials
Leads to sudden cardiac death
Endemic to SE Asia
Term
Cardiac Conduction Disease
Definition
Problem with Na+
Term
Catecholaminergic Polymorphic Ventricular tachycardia
Definition
Prob with RyR auto dom
Term
aPO a1
Definition
Activates LCAT
Term
APO a2
Definition
enhances hepatic lipase activity
Term
Apo b48
Definition
lacks ldl receptor binding domain
exclusive to chylomicrons
Term
Apo B100
Definition
only protein that binds to LDL
one of larges known to man
Term
APo C2
Definition
activates lipoprotein lipase
(to go = 2 = activator)
Term
apo c3
Definition
inhibits lipoprotien lipase
(3 i's in inhibit)
Term
APO d
Definition
assoc w/ lcat
Term
CETP
Definition
exclusive to HDL
cholesterol ester transfer to IDL or VLDL
Term
Apo E (E2 E3 E4)
Definition
Bind to B/E receptors on hepatocytes
E2-homozygote no funct cant clear from plasma
E3-most commmon allele
E4-homozygote has link with alzheimers
Term
Apo (a)
Definition
19 diff alleles
when bound to LDL strongly resembles plasminogen
Term
Chylomicron matured by proteins from
Definition
HDL
Term
HL
Definition
IDL -> LDL
Term
LPL
Definition
nascent VLDL -> IDL
Term
LCAT
Definition
Nascent HDL -> HDL
Term
HMG co-a
Definition
makes cholesterol intracellularly
Rate limiting step
Term
SREBP
Definition
Sterol binding element protein
-Rest on ER and then will break off if cell need cholesterol
Term
Inhibitory of Intracellular Cholesterol
Definition
glucagon, cortisol, statins
Term
Activators of HMG COa
Definition
insulin and SREBP
Term
Weight Gain
Definition
Bad-HDL and VLDL
Good-LDL
Term
Sat fats (bad)
Definition
Bad- LDL
Term
Monounsat
Polyunsat fats
Definition
good for LDL
Term
regular alcohol
Definition
good for LDL
bad for VLDL
Term
Exercise
Definition
Good for HDL
Term
Diabetes Mellitus
Definition
bad for VLDL and LDL
Term
Hypothyroidism
Definition
bad for LDL
Term
Type 1 IL
Definition
low LPL and apo c2
Cant clear chylomicrons
Epigastric pain
tx: low fat diet
Term
Type 2a (aka FH)
Definition
4 classes of LDLr defect
reduced LDL clearance
increased plaques
Term
Type 3 (familial dyslipoprotienemia or broad beta disease)
Definition
xanthomas, high cholesterol increased plaques
Term
type 4 (familial hyperTG)
Definition
increased VLDL assoc with hyperinsulinemia. assoc with insulin resistance and obeseity and alcholol
Term
Type 5
Definition
incr VLDL and chylomicrons unknown cause
Term
Familal hyperalphalipoproteinemia
Definition
incr HDL
beneficial for health
Term
Type 2b
Definition
Incr LDL and delayed clearance of VLDL
Strong assoc with CAD
Term
Xanthelasmas
Definition
usually in younger ppl
dx of hypercholesterolemia
Term
Xanthoma
Definition
usually with hyperTG
Term
Lipid Lowering Drugs
Definition
Statins, Fibrates, Resins, Niacin, Probucul
Term
Tendon Xanthomas
Definition
type 2a and type3
Term
Fibrates
Definition
Clofibrate, Gemfibrozil, Fenofibrate
Term
Resins
Definition
Cholestyramine, Cholestipol
Term
Treating Type 1 (chylomicrons)
Definition
Low fat diet, Gemfibrozil
Term
Tx Type 2a (LDL)
Definition
Statin and Resin
Term
Tx Type 3 (VLDL remnants)
Definition
Gemfibrozil and Statin
Term
Tx Type 4 (VLDL)
Definition
Niacin and Gemfibrozil
Term
Tx type 5 (VLDL and Chylomicrons)
Definition
low fat diet, niacin, and gemfibrozil
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