Term
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Definition
-urethral d/c and/or internal dysuria, pyuria
-No frequency or urgency |
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Term
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Definition
| urethral PAINFUL PURULENT d/c and/or dysuria |
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Term
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Definition
| unilateral pain and swelling in the testes |
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Term
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Definition
| increased d/c and odor with itching/swelling and EXTERNAL dysuria |
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Term
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Definition
| inflammation of columnar epithelium of cervix with yellow d/c and lots of neutros |
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Term
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Definition
-inflammation of upper reproductive tract (ascends from cervix to endometrium and fallopian tubes).
-very painful |
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Term
| Neisseria gonorrhoeae features |
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Definition
-gram negative diplococci
-non-motile
-OX/CAT +
-Aerobic w/ CO2 reqmnt
-ferments glucose
-fastidious
-no capsule |
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Term
| Neisseria gonorrhoeae Virulence |
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Definition
-Pili Adherence(antigenic and phase variation)
-LOS (O Ag, Lipid A endotoxin and Sialic Acid)
-IgA Protease
-Outer Membrane Proteins |
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Term
|
Definition
| Sialic Acid: one of this organisms virulence factors which mimics RBS and helps spread the organism when it disseminates. |
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Term
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Definition
| Can be acq/d via VD: Conjunctivitis/ Opthalmia neonatorum with copious, thick yellow d/c |
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Term
| Neisseria gonorrhoeae transmission |
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Definition
-Sexual contact and VD
-org adgeres to vaginal/urethral columnar epithelium and incubates 3-5 days
-after 1 week, org multiplies and can be shed in genital secretions
-immune response is powerful: influx of PMN (complement activation) |
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Term
| Neisseria gonorrhoeae sx's |
|
Definition
M: urethritis->epididymitis
F: mucopurulent cervicitis/urethritis-> PID and rarely, bacteremia
-10% develop septic arthritis |
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Term
|
Definition
-gram stain of d/c (exudate)will show diplococci and neutros
-culture on Thayer-Martin Medium (choc agar w/ CO2 disk) |
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Term
| Chlamydiae Trachomatis features |
|
Definition
-INTRAcellular parasite, replicates in vacuoles (inclusion bodies)
-cell wall resembles gram -; high lipid content, no peptidoglycans.
-do have penicillin binding proteins
-lysozyme resistant
-LPS has a group specific Ag |
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Term
| Chlamydiae Trachomatis dx |
|
Definition
-Immunofluorescence and PCR from urine.
-*50% of infants born to + mothers will have a + culture. |
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Term
| Chlamydiae Trachomatis Virulence |
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Definition
| -infectious elementary body enters host cell, becomes reticulate body, multiplies. Reforms STABLE/INFECTIVE elementary bodies after 48 hrs which are released from cell by cytolysis |
|
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Term
|
Definition
-serotype D->K causes Chlamydia
-ICN (which can dev to PNA w/o tx) |
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Term
|
Definition
M: non-gonococcal urethritis (NGU); non painful/purulent d/c, dysuria
-30% are asymtomatic
F: Urethritis, Cervicitis, PID (can lead to sterility due to infection lasting years
-70% asymptomatic |
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Term
| Inclusional Conjunctivitis (ICN) |
|
Definition
-signs/sxs withing 5-14 days post birth
-copious, thick yellow d/c (like opthalmia neonatorum)
-babies are tx'd prophylactically
-tx systemically also to prevent PNA (risk is up to 6 months post birth) |
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Term
|
Definition
-Serotype L1-L3 C. Trachomatis
-very rare, ulcerative dz (common in tropical climates)
-causes unilateral supperative adenitis w/ inguinal lymphadenopathy
-iniital papule is self healing but will eventually ulcerate; can dev systemic sxs |
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Term
| Treponema Pallidum features |
|
Definition
-Gram Negative Spirochete causes Syphilis
-microaerophilic
-high lipid content in cell wall (agglutination with Cardiolipin) |
|
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Term
| Treponema Pallidum Virulence |
|
Definition
-Very Motile: has axial filaments and hyalurodinase
-no exotoxins |
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Term
|
Definition
-Innoculation via blood or sexual contact with infectious lesions
-Organism penetrates MM and spreads around body within hours |
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Term
|
Definition
-painless, self healing HARD chancre at site of innoculation
-followed by a 24 week asymptomatic stage |
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Term
|
Definition
-Systemic sxs: fever, CNS sxs, hepatitis, meningitis, glomerular nephritis
-flat/macular reddish brown rash anywhere on body
-condylomata lata: pale/moist/flat papules in moist regions of body
-may be followed by a latent stage lasting 3-30 years |
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Term
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Definition
-destructive necrotic mucocutaneous lesions (Gumma)
-degeneration of CNS w/ CV problems |
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Term
|
Definition
-Spread to fetus by an infected mother after 15 weeks gestation; usually causes spontaneous abortion.
-if fetus reaches FT, may present w/ sxs similar to secondary syphilis (<2 yrs old) OR neuro and physical abnormalities (>2 yrs old) |
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Term
|
Definition
-blood test (will not grow in a culture)
-Non-treponemal Abs (cardiolipin)
-Anti-treponemal Abs (FTA-Abs test) |
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Term
| Haemophilus Ducreyi features |
|
Definition
-gram negative coccobacilli grows in CLUSTERs
-EXTRAcellular organism
-aerobic
-nonmotile
-complex growth req/mnts, GROWS SLOWLY (needs NAD and Factor 10)
-non encapsulated. |
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Term
| Haemophilus Ducreyi Virulence |
|
Definition
-Adhesive Pili
-Cytolethal distending toxin (kills t cells) |
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Term
|
Definition
-2-5 day incubation followed by formation of a small, tender papule that evolves into a PAINFUL ulse (SOFT CHANCRE)
-lymphadenopathy |
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Term
|
Definition
| -hallmark soft chancre clinical presentation, pt hx (travel to dev countries/sexual hx), gram stain |
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Term
|
Definition
-STD's but can also be part of normal flora
-sterol containing membrane
-pleomorphic
-resistant to Penicillin |
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Term
|
Definition
-utilizes urea for growth producing ammonia and CO2.
-infects lower urinary tract
-M: urethritis, dysuria, yellow mucoid d/c
-F: endometritis (can be spread during labor) |
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Term
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Definition
-Utilizes Arginine for growth
-resistant to erythromycin
-causes PID, postabortal/postpartum fever |
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Term
|
Definition
-protozoan found ONLY as a trophozite
-transmission STRICLTY person to person via sexual contact
-M: asymptomatic of NGU
-F: vaginitis, urethritis w/ copious yellow d/c and external dysuria. |
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Term
|
Definition
-Caused by Gardnerella Vaginalis and/or a mycoplasm
-d/c, odor, pain, itching, dysuria
-most ocmmon vaginal infection in women of child bearing age
-risk factorsL new/mult sex partners, IUD placement |
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Term
|
Definition
-caused by Candida Albicans (a dimorphoc fungi)
-infects in hyphae/germ tube form penetrating the MM of mouth, intestines or the vagina
-sxs: pruritis, vaginal soreness, swelling, redness, external dysuria, abn curd like d/c |
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