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Reoviridae
VM 607 Final
24
Veterinary Medicine
Professional
02/28/2012

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Cards

Term
Reoviridae Characteristics
Definition
R-respiratory; E-enteric; O-orphan
non-enveloped, medium sized, dsRNA
10-12 segmented RNA
inner and outer nucleocapsid
Term
Orbivirus Characteristics
Definition
Reoviridae Arbovirus
pH labile, very stable in protein
dsRNA; 10-12 segmented RNA
Term
Rotavirus Characteristics
Definition
Reoviridae
pH stable
dsRNA; 10-12 segmented RNA
outer capsid added in RER
major enteric disease
Term
Reoviridae Entry
Definition
receptor mediated endocytosis
short incubation period
Term
Reoviridae Replication and Release
Definition
in cytoplasm
outer capsid formation depends on host protease cleavage
cytolysis
Term
Reoviridae Tropism
Definition
mucosal epithelium
lymphocytes (some viruses)
neurons (some viruses)
Term
Reoviridae Disease
Definition
caused by Orbivirus and Rotavirus
Term
African Horse Sickness (AHS) Characteristics
Definition
Reportable
affects horses, donkeys, mules, zebra
Term
African Horse Sickness Signs
Definition
acute form - pulmonary form; severe respiratory disease with high mortality
fluid shifts cause shock and colic

Chronic form-cardiac form is less virulent strain; fever, edema, cardiac hemorrhages, hydropericardium
Term
African Horse Sickness Tropism
Definition
lymphoid tissue
respiratory epithelium
Term
African Horse Sickness Transmission
Definition
horizontal - arbovirus
mosquitoes and culicoides, reservoir animals (donkeys, zebra, elephants, dogs)
Term
African Horse Sickness Control
Definition
vector control
don't vaccinate because don't want to mask signs and they are not that effective
quarantine
Term
Bluetongue Characteristics
Definition
worldwide disease
sheep, deer, cattle, goats
arbovirus
Term
Bluetongue Signs
Definition
subclinical to severe febrile vascular disease
deer infected the most
cattle and goats could be amplifying reservoirs
Term
Bluetongue Tropism
Definition
hematopoietic cells
endothelial cells
Term
Bluetongue Signs
Definition
cyanotic - "Blue tongue"
circulatory disturbances
lesions on oral mucosa, tongue, coronary bands
edema, hemorrhages, fetal abnormalities
vesicular lesions in cattle
can't eat or drink
Term
Bluetongue Transmission
Definition
horizontal - arbovirus (main)
verticle - transplacental, semen
Term
Epizootic Hemorrhagic Disease Characteristics
Definition
in deer in USA
Ibaraki disease in cattle (foreign animal disease)
arbovirus
Term
Epizootic Hemorrhagic Disease Signs
Definition
clinically resembles bluetongue
Term
Rotavirus Tropism
Definition
enteric mucosa of differentiated epithelium
Term
Rotavirus Pathogenesis
Definition
short incubation period
direct invasion of enterocytes
Term
Rotavirus Transmission
Definition
horizontal - orofecal
Term
Rotavirus Disease
Definition
milk scours
affects young production animals
Term
Rotavirus Control
Definition
sanitation, isolate ill animals
vaccinate local mucosal immunity to increase colostral antibody titers
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