Shared Flashcard Set

Details

Rana Alquarashi
molecular and cellular radiation biology
20
Medical
Not Applicable
05/22/2019

Additional Medical Flashcards

 


 

Cards

Term
Ionizing Radiation
Definition
Damages living systems by ionizing the atoms compromising the molecular structures of the systems.
Term
Three characteristics of ionizing radiation are:
Definition
  • Charge
  • Mass
  • Energy
Term
Linear energy transfer
Definition
The average energy deposited per unit length of track.
Term
Wave-particle duality
Definition
streams of particles called photons, each of which has no mass and no charge.
Term
Examples of low LET radiation
Definition
  • x-rays
  • Gamma Rays 
Term
Examples of High-Let Radiation
Definition
  • Alpha particles,
  • Ions of heavy molecules,
  • Charges particles released from interactions between neutrons and atoms,
  • low-energy neutrons

 

Term
High- Let radiation includes particles that possess substantial:
Definition
  • Mass
  • Charge 
Term
Neutrophils
Definition
a type of white cell play an important roll in fighting infection.
Term
Permanent sterilization occurs at
Definition
5 to 6 Gyt
Term
where are lymphocytes manufactured in the human body?
Definition
Bone marrow
Term
Examples of distorted chromosomes:
Definition
  • Anaphase bridge
  • Dicentric chromosomes
  • Ring chromosomes
Term
Radiosensitivity of the individual cell
Definition
governs the radiation dose required to cause apoptosis.
Term
3 levels of radiation damage:
Definition
  • Molecular
  • cellular
  • organic systems
Term
Oxygen enhancement ratio (OER)
Definition
the ratio of the radiation dose required to cause a particular biologic response of cells or organisms in an oxygen-deprived environment to the radiation dose required to cause an identical response under normal oxygenated conditions.
Term
In living system, biologic damage stemming from exposure to ionizing radiation is observed on three levels:
Definition
  • Molecular
  • Cellular
  • Organic systems
Term
Mitotic delay reasons:
Definition
  • Alteration of a chemical involved in mitosis
  •  Proteins required for cell division not being synthesized
  • A change in the rate of DNA synthesis after irradiation
Term
Radiosensitive cells
Definition
  • Basal cells of the skin
  • Blood cells such as lymphocytes and erythrocytes 
  • intestinal crypt cells
  • Reproductive (germ) cells

 

Term
As the ___ of radiation increases, so do biologic effects.
Definition
LET
Term
Muscle tissue
Definition
is relatively insensitive to radiation.
Term
Most radiosensitive blood cells
Definition
Lymphocytes
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