Shared Flashcard Set

Details

RA
immunity
25
Nursing
Not Applicable
08/19/2012

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Cards

Term
What virus is associated with RA?
Definition
Epstein-Barr
Term
Risk factors of RA?
Definition
European Americans
Women 40-60yrs
Family history
Heavy smokers
Term
Gel phenomenon
Definition
morning stiffness lasting for 45min to several hrs
Term
RA course is generally
Definition
progressive w/ remissions and exacerbations
Term
Affected joints appear?
Definition
red, hot, swollen; boggy and tender to palpation
Term
Most common form of arthritis in older adults?
Definition
Osoarthritis
Term
Pannus
Definition
long term, severe proliferation of the synovial intimal layer
Term
What diagnostic tests are used for RA?
Definition
ESR (elevated)
RF (elevated)
CBC - anemia
C-reactive protein (elevate)
Term
Appearance of synovial fluid in RA
Definition
increased turbidity(cloudiness)
Decreased viscosity
Increased protein and WBC levels
Term
Medications are used with caution in older adults because of
Definition
increased risk of toxicity
Term
Early manifestations RA?
Definition
joint inflammation
low grade ever
faigue
weakness
anorexia
paresthesias
Term
Late joint manifestations RA?
Definition
Deformities- swan neck or ulnar deviation
Moderate to severe pain and morning stiffness
Term
Late systemic manifestations?
Definition
Osteoporosis
Severe fatigue
Anemia
Weight loss
Subcutaneous nodules
peripheral neuropathy
vasculitis
pericarditis
fibrotic lung disease
jogren's syndrome
renal disease
feltys syndrome
Term
Normal Sed rate?
Definition
Male: up to 15 mm/hr
Women: up to 20 mm/hr
Term
Baker's cysts
Definition
enlarged poplteal bursae behind the knee
Term
Why are RA pts at increased risk for CHD?
Definition
C-reactive proteins
Low HDL
Elevated cholesterol and triglycerides and high homocysteine
Meds- Methotrexate and steriods
Term
Uveitis is most commonly a complication of?
Definition
Juvenile RA
Term
Pericarditis manifestations?
Definition
Chest pain radiating to back relieved by sitting up and leaning forward. Worsened by lying down
Dry cough, fever and anxiety
Auscultation-Friction rub
CHF
JVD
Peripheral edema
Term
Vaculitis manifestions
Definition
Fever, weight loss, palpable purpura, hypertension, gangrene, nose bleeds, bloody cough abdominal pain, bloody stools, perforations andglomerulonephriti
Term
First drug prescribed in the treatment of RA?
Definition
Aspirin
Term
Therapeutic blood level for aspirin and full anti inflammatory effect?
Definition
15-30 mg/dL
4 g/day
Term
Toxic does of aspirin produces?
Definition
Tinnitus and hearing loss
Term
Methotrexate- most frequent side effects?
How are they controlled?
Definition
Gastric irritation and stomatitis
Controled with folic acid
Term
Hydroxycholoroquine (Plaquenil)
classification?
Adverse effects?
Definition
Antimalarial
3-6 months before desired effects
Pigmentary retinitis and vision loss
Term
RA is
Definition
chronic, progressive, systemi inflammatory autoimmune disease process that affects primarily the synovial joints
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