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PWA Unit 4 Chapter 8
Circulation and Immunity
62
Biology
11th Grade
02/23/2009

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Term
Anemia
Definition
a condition in which there is a deficiency of red blood cells or too little hemoglobin inside the red blood cells in the bloodstreams; results in a deficiency of oxygen in the body tissue (8.2)
Term
Agglutination
Definition
clumping together; for example clumping of red blood cells that occurs when imcompatible blood types are mixed (8.3)
Term
Anitbody
Definition
proteins that recognize foreign substances in the body and neutralize or destroy them (8.3)
Term
Anitbody-Mediated Immunity
Definition
component of the immune system that involves the activation of lymphocytes and the secretion of antibodies specitic to a specific antigen; also known as specific defence; compare cell-mediated immunity (8.3)
Term
Antigen
Definition
molecule found on the surface of cells and pathogens; can be recognized by the body's immune system (8.3)
Term
Aorta
Definition
major artery that carries oxygenated blood away from the heart to all regions of the body except the lungs (8.1)
Term
Arterionsclerosis
Definition
general term used to describe several conditions in which the walls of the arteries thicken and lose some of their elastic proerties, thus becoming harder; the most common type is called atherosclerosis (8.1)
Term
Artery
Definition
blood vessel that carries oxygen-rich blood away from the heart (8.1)
Term
Atrioventricular (AV) Node
Definition
bundle of specialized muscle tissue located in the wall of the right atrium; receives electrical stimulus from the sinoatrial node and transmits this impulse over the walls of the ventricles to start their contraction; compare sinoatrial node (8.1)
Term
Atrium (atria)
Definition
one of the two upper chambers of the heart that collects blood flowing into the heart; right atrium receives blood from systemic circulation, and the left from pulmonary circulation (8.1)
Term
Autoimmune Disorder
Definition
condition in which T cells or antibodies mistakenly attack the body's own cells as if they had foreign antigen (8.3)
Term
B Cell
Definition
lymphocyte that is activated by a specific antigen to produce memory B cells and plasma cells; plasma cells produce antigen specific antibodies; also known as B lymphocyte; compare T cell (8.3)
Term
B Lymphocyte
Definition
see B cell (8.3)
Term
Blood Transfusion
Definition
introduction of ablood or blood products into an artery or vein (8.3)
Term
Bundle of His
Definition
a bundle of specialized fibres through which an electrical signal is transmitted from the atrioventricular (AV) noce, initiating the contraction of the right and left ventricles (8.1)
Term
Cell-Mediated Immunity
Definition
non-specific component of the immune system that involves the activation of white blood cells, specifically macrophages, neutrophils and monocytes, rather than the production of antibodies; also known as non-specific defence; compare antibody-mediated immunity (8.3)
Term
Circulatory System
Definition
in animals, the system of vessels that transports blood, and the cells, and substances suspended and dissolved in blood, throughout the body (8.1)
Term
Coronary Pathway
Definition
in animals, the circulatory pathway that supplies oxygen-rich blood to and carries deoxygenated blood from the muscle tissue of the heart (8.1)
Term
Diastolic Pressure
Definition
the lowest blood pressure exerted before the ventricles contract; compare systolic pressure (8.1)
Term
Granulocyte
Definition
a type of white blood cell containing granules in its cytoplasm; the three types of granulocytes are neutrophils, basophils, and eosinophils (8.2)
Term
Blood Pressure
Definition
pressure exerted against blood vessel walls as circulating blood passes through the vessels (8.1)
Term
Erythrocyte
Definition
blood cell that contains the respiratory protein hemoglobin and is specialized for oxygen transport; also known as red blood cell (8.2)
Term
Formed Portion
Definition
solid portion of the blood consisting of red blood cells, white blood cells, and platelets (8.2)
Term

Purkinje Fibre

Definition
in the heart, a fast-conducting muscle fibre that initiates the almost simultaneous contraction of all cells of the right and left ventricles; signal for this contraction is initiated by the sinoatrial (SA) node and is relayed through the atrioventricular (AV) node and the bundle of His (8.1)
Term
Red Blood Cell
Definition
see erythrocyte (8.2)
Term
Helper T Cell
Definition
lymphocyte that, upon recogizing an antigen, gives off chemical signals that stimulate certain immune cells (macrophages, B cells, and other T cells) to perform their respective functions (8.3)
Term
Hemoglobin
Definition
iron-containing respiratory pigment found in red blood cells that transports oxygen from the lungs to body tissues (8.2)
Term
Hemolysis
Definition
the bursting of red blood cells (8.3)
Term
Hemophilia
Definition
inherited, life-threatening disorder resulting from insuffcient clotting proteins in the blood (8.2)
Term
Immunity
Definition
ability of the body to protect itself from foreign, disease-causing agents through a specific defence mechanism that uses antibody proteins to recognize, neutralize, and destroy foreign substances (8.3)
Term
Killer T Cell
Definition
cytotoxic lymphocyte that binds with infected cells and destroys them by puncturing a hole in their membrane; may be activated indirectly by chemical signals from a helper T cell or directly by the presence of the invading pathogen and accociated antigens (8.3)
Term
Leucocyte
Definition

see white blood cell (8.2)

Term
Leukemia
Definition
cancer of the white blood cells; two main types are myeloid and lymphoid (8.2)
Term
Lymph
Definition
interstitial fluid carried throughout the body in the lymphatic circulatory system; is either colourless or pale yellow, with a composition much like the plasma of blood (8.3)
Term
Lymphatic Circulatory System
Definition
network of glands and vessels that carry lymph throughout the mammaliam body; helps to maintain the balance of fluids in the body (8.3)
Term
Lymphocyte
Definition
type of white blood cell involved in both cell-mediated and antibody-mediated immunity; types include B and T cells (8.2)
Term
Macrophage
Definition
phagocytic white blood cell that develops from a monocyte; acts as a scavenger, ingesting dead cells and foreign material, and killing micro-organisms; macrophages also stimulate other cells in the immune system (8.3)
Term
Memory T Cell
Definition
lymphocyte that carries receptors for a specific foreign antigen that was encountered in an earlier infection or through a vaccination; memory T cell quickly promote an immune response if the same antigen is re-encountered in a subsequent infection (8.3)
Term
Non-Specific Defence
Definition
see cell-mediated immunity (8.3)
Term
Phagocytosis
Definition
process by which a cell ingests another cell, bacterium, or particle of organic matter (8.3)
Term
Plasma
Definition
fluid portion of the blood, made up of water plus dissolved gases, protein, sugars, vitamins, minerals, hormones, and waste products (8.2)
Term
Platelet
Definition
component of the formed portion of the blood, consisting of fragments of cells that are created when larger cells in the bone marrow break apart; contain no nucleus and plays a key role in blood clotting (8.2)
Term
Pulmonary Artery
Definition

blood vessel that carries blood from the heart to the lungs (8.1)

Term
Pulmonary Pathway
Definition
in animals, the circulatory pathway that carries oxygen - poor blood from the heart to the lungs and oxygen - rich blood from the lungs to the heart (8.1)
Term

Pulmonary Vein

Definition

blood vessel that carries blood from the lungs to the heart(8.1)

Term
Purkinje Fibre
Definition

in the heart, a fast-conducting muscle fibre that initiates the almost simultaneous contraction of all cells of the right and left ventricles; signal for this contraction is initiated by the sinoatrial (SA) node and is relayed through the atriventricular(AV) node and the bundle of His (8.1)

Term
Rh Factor
Definition
group of antigens found in most red blood cells; people with the Rh factor on their red blood cells are termed Rh positive (Rh+) and people without it are Rh negative (Rh-) (8.3)
Term
Septum
Definition
in the heart, the muscular wall that separates the two ventricles and the two atria (8.1)
Term
Sinoatrial (SA) Node
Definition
bundle of specialized muscle tissue located in the wall of the right atrium of the mammalian heart; generates an electrical impluse that stimulates cardiac muscle fibres to contract and relax rhythmically, producing a regular heartbeat; also known as pacemaker; compare atrioventricular node  (8.1)
Term
Specific Defence
Definition
see antibody-mediated immunity (8.3)
Term

Suppressor T Cell

Definition
lymphocyte that slows and suppresses the cell-mediated immune response to an antigen to ensure that healthy tissues are not destroyed (8.3)
Term
Systemic Pathway
Definition
in animals, the circulatory pathway that carries oxygen-rich blood from the heart to the body tissues, and oxygen-poor blood from the tissues back to the heart (8.1)
Term

Systolic Pressure

Definition
maximum blood pressure exerted during ventricular contraction; compare diastolic pressure (8.1)
Term
T Cell
Definition
lymphocyte that is primarily responsible for cell-immediated immunity; roles include activation of certain immune cells, destruction of invading pathogens, suppression of cellular immunity, and promotion of immune response upon reinfection; types include helper,killer, suppressor, and memory T cells; compare B cell (8.3)
Term
T Lymphocyte
Definition
see T cell (8.3)
Term
Valve
Definition
membranous extension of a vessel or the heart wall that opens and closes, ensuring one-way fluid flow (8.1)
Term
Vasoconstriction
Definition
decrease in the diameter of blood vessels; vasoconstriction near the skin conserves body heat (8.2)
Term
Vasodilation
Definition
 expansion in the diameter of blood vessels; vasodilation near the skin brings more blood to the surface to help reduce body temperature (8.2)
Term
Vein
Definition
blood vessel that carries oxygen-poor blood to the heart (8.1)
Term
Vena Cava (vena cavae)
Definition
one of two large vessels, the superior and inferior vena cavae, that open into the right atrium of the heart (8.1)
Term
Ventricle
Definition

one of the two lower chambers of the heart; each ventricle receives blood from one of the atria and pumps it into systemic or pulmonary circulation

(8.1)

Term
White Blood Cell
Definition
colourless blood cell that protects the body from infection by the way of the immune response, and also plays a role in allergic reactions and inflammation; three types include granulocytes, monocytes, and lymphocytes; also known as leucocyte (8.2)
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