Term
| Cause of Brochogenic Lung Cancer |
|
Definition
| Smoking, Ionizing Radiation, Asbestos, Air Pollution |
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Term
| Precusor lesions to Brochogenic Lung Cancer |
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Definition
A)Squamous dysplasia/carcinoma In-Situ
B)Atypical Adenomatous Hyperplasia
C)Diffuse Idiopathic Pulmonary Neuroendocine Cell Hyperplasia |
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|
Term
| What is the 1-yr and 5-yr survival rates for brochogenic carcinoma? |
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Definition
|
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Term
| What is the location of each of the Bronchogenic Carcinomas? |
|
Definition
Squamous: Central
Adeno: Peripheral
Bronchioalveolar:Peripheral
Small Cell: Central |
|
|
Term
| What is the prodominant sex affected by each of the Brochogenic Lung Carcinomas |
|
Definition
Squamous: Men
Adeno: Women
Brochioalveolar: Equal
Small Cell: Women Slightly |
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|
Term
| Describe the growth pattern of each of the Bronchogenic Carcinomas |
|
Definition
Squamous: Metaplastic Epithelium-> Intraluminal mass or Peribrochial->Mediastinum/Carina
Adeno: Slower Growth
Bronchioalveolar: Along preexisting Interstitium
Small Cell: Aggressive with hemagenous spread |
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|
Term
| Describe the metstatic processes of each of the brochogenic carcinomas |
|
Definition
Squamous: Late metastasis
Adeno: Early metastasis
Bronchioalveolar:
Small Cell: Most Malignant |
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|
Term
| What cell is small cell bronchogenic carcinoma derived from |
|
Definition
|
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Term
| What bronchogenic carcinma can cause a cavitary lesion |
|
Definition
|
|
Term
| what are the most likely sites of metastasis of brochgenic carcinoma |
|
Definition
| Adrenals, Liver, Brain, Bone |
|
|
Term
| What is large cell carcinoma probably derived from |
|
Definition
| Undifferentiated Squamous or Adenocarcinoma |
|
|
Term
| What are the probable causes of the increase in incidence of Adenocarcinomas |
|
Definition
Filters
Women Smokers
Less Squamous makes adeno % increase |
|
|
Term
| Paraneoplastic substances of bronchogenic carcinoma esp associated with Squamous cell and Small cell |
|
Definition
ADH ACTH, PTH, PGE, Calcitonin, Serotonin, Bradykinin, Gonadotropins
Squamous: Hypercalcemia
Small Cell: ADH and ACTH
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Term
| Clinically Observed Complications of Bronchogenic Carcinomas |
|
Definition
Lambert-Eaton Myathnia Gravis
Peripheral Neuropathy
Acanthosis nigricans
Leukomoid Rxns
Hypertrophic Pulmonary Osteoarthropathy
Pancoast Tumor: Apex-> Tracheal Structures->Horner's Syndrome |
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|
Term
| What are the non-bronchogenic Carcinoma cancer diseases |
|
Definition
Hemarthoma
Metastastsis to the Lung
Carcinoid |
|
|
Term
| What age group is typically affected by Carcinoid Tumors |
|
Definition
|
|
Term
| What is the life exectancy after a mesothelioma diagnosis |
|
Definition
|
|
Term
| Identification of small cell carcinoma with light microscopy |
|
Definition
| Small cells with salt and pepper nuclei |
|
|
Term
| What are the most common symptoms of lung cancer? |
|
Definition
| Cough, Weight Loss, Chest pain, Dyspnea |
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