Term
| Ohio River Valley, Mississippi River, Bats/Avian Feces, Ground-moving |
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Definition
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|
Term
| Southwest, Dust clouds, Earthquakes |
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Definition
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|
Term
| Rural Southeast and Northcentral US, 20-50 yr old Male |
|
Definition
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|
Term
| Warm Wet Climate, S.America/Mexico |
|
Definition
| Paracoccidiodes brasiliensis |
|
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Term
| Manifestations of Histoplasmosis |
|
Definition
90% Asymptomatic
Mild Flu<->Fulminating Milliary Disease
Reticuloendothelial Organ Damage |
|
|
Term
| Manifestations of Coccidiodes |
|
Definition
50-60% Asympomatic 40% Flu, 1-10% Severe
Flu-like 1-4 wks->Dissemination Ulcerating Granulomatous Skin Lesions Meningeal Infection-> CNS Signs
Erethema Nodosum: 20% Women |
|
|
Term
| Manifestations of Aspergillious |
|
Definition
Allergic:SerineProtease->Rhinitis/Wheeze
Chronic Exp->SevereAsthma->Brochiectasis
Pulmonary: Asympt<->Hemoptasis
Invasive
Vessel Invasion |
|
|
Term
| Risk Factors for each Aspergillus Infection |
|
Definition
Allergic:CF/CF Carrier,Atopy,High Exposure Pulmonary:TB,Sarcoid,Emphysema,Cavitary Cancer
Invasive: Immunosupression(Glucorticoids,Chemo) |
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|
Term
| Diagnosis of Histoplasmosis |
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Definition
Clinical suspicion
Skin Test: Histoplsmin Antigen
Staining: Methanemina-Silver or PAS of Sputum or Marrow
Culture: Mold(25),Yeast(37) |
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|
Term
|
Definition
Suspicion: Flu-like after Southwest visit
Skin Test: After 1-2 Wks
Serology: Precipatin(1-2wks), Complement Fix(2-3mths)=Disseminated
Direct Exam
Culture: Mold at 25, Yeast not culturable |
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|
Term
|
Definition
Allergic: Skin Test-Wheal/flare with late arthus
Ball: CXR
Invasive: Histopath-Septate Hyphae with 45 branch |
|
|
Term
|
Definition
Direct Exam: Pus, Sputum, Nasal, cerebral
Culture
Histopath: Aseptate, 90 Branch |
|
|
Term
| Diagnosis of Blastomyces dermatitidis |
|
Definition
Sputum/Biopsy Ulcer:Broad-Based Bud
Culture(25 mold,37 yeast) |
|
|
Term
| Diagnosis of Paracoccidiodes brasiliensis |
|
Definition
Culture: Mold (25), Yeast (37), Parent Cell w/ Peripheral Bud
Skin Test
|
|
|
Term
| Manifestations of Zygomyces |
|
Definition
Rhinocerebral: Occular and Palate Lesions
Pulmonary: Bronchitis/Pneumonia
Gastrointestinal |
|
|
Term
| Manifestations of Blastomyces dermatitidis |
|
Definition
Respiratory->Skin, Sub-Cut, Bone
Lesions:Palpable->Ulceration->
Central healing
Death: 90% if Untreated |
|
|
Term
| Manifestations of Paracoccidiodes brasiliensis |
|
Definition
| Respiratory-> Chronic Granulomatous(Pulm and Lymph)->Mucocutaneous Lesion |
|
|
Term
| Treatment of Histoplasmosis |
|
Definition
Amphoterin B or Oral/IV Itraconazole
Only tx severe pulm, cavitary, acute/chronic disseminated |
|
|
Term
|
Definition
Meningitis: Amphotericin B
Chronic Pulmonary: Azoles
Surgery |
|
|
Term
|
Definition
Allergic: Corticosteroid w/ or w/o Intraconazole
Ball: Amphotericin B + Fluctosine, Surgery
Invasive: Surgical Drain, Increase Immune, Amphotericin B and/or Azole, If Refractory to Ampho: Caspofungin or Voriconazole |
|
|
Term
|
Definition
Surgical Drain, Increase Immune, Amphotericin B and/or Azole, If Refractory to Ampho: Caspofungin or Voriconazole |
|
|
Term
| Treatment of Blastomyces dermatitidis |
|
Definition
Acute: Amphotericin B
Chronic: Azoles |
|
|
Term
| Treatment of Paracoccidiodes brasiliensis |
|
Definition
Disseminated: Ampho B
Pulm: Azoles |
|
|
Term
| Species of Aspergillus and which is the most common pathogen |
|
Definition
| Fumigatus(Most Common), Flavus, Niger |
|
|
Term
| Infectious form of Cocciodes immitis |
|
Definition
|
|
Term
| Epidemiology of Zygomyces |
|
Definition
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