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PT 100 Blood & Lymphatic
definitions
116
Other
Undergraduate 2
04/27/2008

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Term
erythrocytes (RBCs)
Definition
blood cells that specialize in transporting O2 and CO2; red blood cells
Term
hematopoiesis
Definition
the process of blood cell formation within the red bone marrow
Term
hemoglobin
Definition
an abundant protein in RBCs that has a high bonding affinity for O2 and CO2
Term
immunity
Definition
the status of being immune or successfully resistant to infection
Term
leukocytes (WBCs)
Definition
blood cells specializing in protecting the body from infection; white blood cells
Term
lymph
Definition
a yellowish fluid channeled through lymphatic capillaries, vessels and trunks
Term
lymph nodes
Definition
pea-sized organs filled with WBCs that filter out foreign materials from the lymph
Term
lymphatic capillaries
Definition
microscopic, blind-ended vessels into which interstitial fluid diffuses
Term
lymphatic nodules
Definition
clusters of lymphatic tissue, composed of WBCs that are embedded within the walls of the large intestine; Peyer's patches
Term
lymphatic trunks
Definition
large vessels that carry lymph to the subclavian veins near the heart
Term
lymphatic vessels
Definition
vessels that carry lymph from lymphatic capillaries to lymphatic trunks
Term
lymphocyte
Definition
a type of WBC that plays the primary role in conferring immunity and forms the bulk of lymphatic tissue; includes T cells and B cells
Term
pathogen
Definition
any microorganism that causes disease, such as a virus, bacterium, protozoan or fungus
Term
toxin
Definition
a poisonous substance produced by a cell or tissue various parts of the body
Term
antibody
Definition
proteins released by activated B cells (plasma cells) which selectively bind to antigens during an immune response
Term

antibody-generating (antigen)

Definition

any foreign substance, usually a protein, against whcih an immune response is directed

Term
basophil
Definition
a WBC that responds to antigens by releasing substances including histamine and serotonin, which cause inflammation
Term
B cell
Definition

1 of 2 types of lymphocytes, B cells respond to an infection by secreting antibodies which require activation by a helper T cell; B cell activiry is called an acquired immune response

Term
blood clot
Definition
a combination of protein fibers and trapped blood cells prdouced to slow or stop blood loss after an injury
Term
coagulation
Definition
the process of blood clot formation
Term
fibrinogen
Definition
a dissolved protein in blood that is the precursor for fibrin, which is the main component in a blood clot
Term
neutrophil
Definition
WBCs that fight infection by phagocytizing unwanted foreign particles
Term
phagocytosis
Definition
the process of "cell eating", during which a particle is ingested into the cell's cytoplasm and digested
Term

plasma

 

Definition
the liquid portion of blood
Term
platelets
Definition
cell fragments in the blood that facilitate the formation of blood clots; thrombocytes
Term
serum
Definition
the fluid portion of plasma after fibrinogen has been removed
Term
spleen
Definition
a soft, oblong organ located lateral and slightly posterior to the stomach in the abdominal cavity; it serves as a storage site for RBCs and WBCs
Term
T cell
Definition
a type of lymphocyte that mounts an immune response that includes activation of otehr WBCs, direct destruction of foreign cells, and establishment of a memory of the infection to create immmunity; T cell activity is called an innate immune response
Term
thoracic duct
Definition
the main lymphatic trunk
Term
tonsils
Definition
small, oval organs in the throat region that are filled with WBCs that fight infection
Term
anisocytosis
Definition
presence of RBCs of unequal size
Term
bacteremia
Definition
presence of bacteria in the bloodstream
Term

erythropenia

Definition
abnormally reduced number of RBCs
Term
hemolysis
Definition
rupture of the RBC membrane
Term

hemorrhage

 

Definition
loss of blood from the circulation
Term
macrocytosis
Definition
abnormally large-sized RBCs
Term
poikilocytosis
Definition
large, irregularly shaped RBCs
Term
polycythemia
Definition
abnormal increase in the number of erythrocytes in the blood
Term
splenomegaly
Definition
abnormal enlargement of the spleen
Term
toxemia
Definition
presence of toxins in the bloodstream
Term
acquired immune deficiency syndrome (AIDS)
Definition
caused by human immunodeficiency virus (HIV), which disables the immune response by destroying mainly helper T cells
Term
allergy-
Definition
a response to an allergen
Term
anaphylaxis
Definition
an immediate reaction to an antigen that includes rapid inflammation and system- wide smooth muscle contractions
Term
anemia
Definition
a reduced ability of RBCs to deliver O2 to tissues resulting from a reduction of circulating RBCs, the amount of hemoglobin or the volume of RBCs
Term
aplastic anemia
Definition
anemia characterized by the failure of red bone marrow to produce RBCs
Term
autoimmune disorder
Definition
any one of several diseases that are caused by a person's own immune response attacking otherwise healthy tissues
Term
botulism
Definition
a form of poisoning caused by the ingestion of food contaminated with the toxin produced by the bacterium Clostridum botulinum
Term
diphtheria
Definition
a disease caused by a bacterium and its toxin, resulting in inflammation of mucous membranes, primarily in the mouth and throat
Term
dyscrasia
Definition
a general term for an abnormal condition of the blood
Term
erythroblastosis fetalis
Definition
a blood disorder resulting from incompatibility between a fetus with Rh+ blood and its mother with Rh- blood, which causes the destruction of fetal RBCs and requires blood transfusion to save the fetus; Rh mismatch; hemolytic disease of newborn
Term
fungemia
Definition
a fungal infection distributed by way of the blood stream
Term
gas gangrene
Definition
the infection of a wound caused by various anaerobic bacteria that produces a fermentation gas, necrosis, and septicemia
Term
hemochromatosis
Definition
inherited disorder that results in an excessive accumulation of iron deposits in the body
Term
hemophilia
Definition
an inherited bleeding disorder that results from defective clotting proteins involved in blood coagulation
Term
Hodgkin's disease
Definition
cancer of the lymphatic tissue
Term
immunodeficiency
Definition
a conditon resulting from a defective immune response
Term
immunosuppression
Definition
reduction of an immune response
Term
infection
Definition
a multiplication of disease-causing microorganisms
Term
inflammation
Definition
a swelling of body tissue caused by the movement of plasma inrto the extracellular space to produce edema or fluid accumulation in tissue
Term
influenza
Definition
a viral disease characterized by a temporary inflammation of mucous membranes and fever
Term
iron deficiency anemia
Definition
anemia that is caused by a lack of iron
Term
leukemia
Definition
cancer of the red bone marrow, which is the blood forming tissue
Term
lymphadenitis
Definition
inflammation of the lymph nodes
Term
lymphadenopathy syndrome (LAS)
Definition
"disease of the lymph nodes"
Term
lymphoma
Definition
a tumor originating in lymphatic tissue
Term
malaria
Definition
a disease caused by a parasitic protozoan that  infects RBCs, which is carried by Anopheles mosquitos
Term
mononucleosis
Definition
a viral disease characterized by enlarged lymph nodes, atypical lymphocytes, sore throat, fever and fatigue
Term
myelodysplasia
Definition
bone marrow disorder characterized by the proliferation of abnormal stemn cells, which usually develops into a form of leukemia
Term
nosocomial infections
Definition
a disorder, usually bacteria infections,contracted during a hospital stay; often due to antibiotic-resistant strains of Staphylococcus
Term
pernicious anemia
Definition

anemia caused by an inadequate supply of folic acid (vitamin B12)

 

Term
plague
Definition
any infectious disease of wide prevalence or excessive mortality; more specifically the bubonic plague
Term
rabies
Definition

a bacterial infection spread from the mouth of an infected animal, usually by way of a bite

Term
septicemia
Definition
a systemic disease caused by a presence of bacteria and their toxins in the circulating blood
Term
sickel cell anemia
Definition
an inherited, chronic anemia that is characterized by defective hemoglobin that causes RBCs to become misshapen
Term
staphylococcemia
Definition
the presence Staphylococci bacteria in the blood; staph infection
Term
tetanus
Definition
a disease caused by the powerful neurotoxin released by the common bacterium Clostridum tetani
Term
thymoma
Definition
a tumor originating in the thymus gland
Term
antibiotic
Definition
a therapeutic treatment in which a substance with known toxicity to bacteria is administered
Term
anticoagulant
Definition
a chemical agent that reduces the clotting process
Term
antiretroviral therapy
Definition
application of drugs to battle against a class of viruses that tend to mutate quickly, known as retroviruses
Term
attenuation
Definition
a process in which pathogens are rendered les virulent, prior to their incorporation into a vaccine preparation
Term
autologous transfusion
Definition
transfusion of blood donated by a patient for personal use
Term
blood chemistry
Definition
a test or series of tests on plasma to measure the levels of particular components
Term

blood culture

Definition
a test to determine infection in the blood by placing a blood sample on a nutritive media in a n effort to grow populations of bacteria for analysis
Term
blood transfusion
Definition
introduction of blood, blood products, or a blood substitute into a patient's circulation to restore blood volume to normal levels
Term
coagulation time
Definition
a timed blood test to determine the time required for a blood clot to form
Term
complete blood count (CBC)
Definition
a common lab test that provides diagnostic info of a patient's general health
Term
differential count
Definition
microscopic count of the number of each type of WBC using a stained blood smear
Term
erythrocyte sedimentation rate (ESR)
Definition
a timed test to measure the rate at which RBCs fall through a volume of plasma to provide info on their hemoglobin content
Term

hematocrit (HCT or Hct)

Definition
a test that measures the percentage of RBCs in a  volume of blood
Term
hematology
Definition
the general field of medicine focusing on blood-related disease
Term
hemoglobin (HGB or Hgb)
Definition

a test that measures the level of hemoglobin in RBCs (in grams)

Term
hemostasis
Definition
stoppage of bleeding
Term
homologous transfusion
Definition

transfusion of blood that is voluntarily donated by another person

Term
immunization
Definition
a procedure that provides immunity against a particular antigen
Term
immunology
Definition
the study concerned with immunity and allergy
Term
immunotherapy
Definition
used in the treatment of infectious disease, it is the use of agents to activate or strengthen the immune response
Term
lymph node dissection
Definition
removal of lymph nodes for pathological study to assist in diagnosis; lymph node biopsy
Term
lymphadenectomy
Definition
excision of a lymph node
Term
lymphadenography
Definition
the process of x-ray photography of the lymph nodes following injection of a contrast medium
Term
lymphadenotomy
Definition
incision into a lymph node
Term
lymphangiography
Definition
the process of x-ray photography of lymphatic vessels following injection of a contrast medium
Term
phresis
Definition
removal of a donor's blood, which is then separated into blood components, with one portion retained for use and the remainder returned to the donor
Term
platelet count (PLT)
Definition
calculation of the number of platelets in blood
Term

prophylaxis

Definition
any treatment that tends to prevent the onset of an infection or other type of disease
Term
red blood count (RBC)
Definition
measures the number of RBCs per cubic centimeter (cc)
Term
splenectomy
Definition
excision of the spleen
Term
splenopexy
Definition
surgical fixation of the spleen
Term
thrombolysis
Definition
the process of dissolving a blood clot
Term

thymectomy

Definition
excision of the thymus gland
Term
vaccination
Definition
the inoculation of a culture that has reduced virulence as a means of providing a cure or prophylaxis (prevention)
Term
vaccine
Definition
any preparation used to activate an immune response
Term
white blood count (WBC)
Definition
measures the number of WBCs per cubic centimeter
Term
INR
Definition
international normalized ratio
Term
PT
Definition
prothrombin time
Term
PTT
Definition
partial thromboplastin time
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