Term
| Every drug has a __________? |
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Definition
1. MOA
Mechanism of Action
The MOA describes how a drug works in the body
2. Side effects |
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Term
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Definition
An agonist stimulates the receptor to do what the receptor is designed to do.
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Term
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Definition
| An antagonist blocks the receptor from being stimulated. |
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Term
| What is an inverse agonist? |
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Definition
An inverse agonist is the opposite of an agonist. The inverse agonist binds to a receptor site and produces the opposite effects as the original agonist.
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Term
| What is the opposite of an agonist? |
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Definition
| An inverse agonist is the opposite of an agonist. |
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Term
| Among agonist, inverse agonist, and antagonist; which has the strongest reaction on the receptor site? |
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Definition
| The antagonist has the strongest reaction because it causes the receptor site to be blocked. |
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Term
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Definition
| A prodrug is a drug that is only activated by the liver. It remains inactivated until it reaches the liver. |
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Term
| What is the Prototypic Prodrug? |
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Definition
Coedine is the Prototypic Prodrug;
it contains the 2% Morphine |
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Term
| Ways in which medications can be given |
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Definition
Orally-By mouth;Absorption into the blood stream in 20 mins
Subcutaneously-Under the skin
Intraveneously-Into the vein; reaches the brain in 15 secs
Transdermally- On the skin
Intramuscularly- By a shot into the muscle
Nasally- Through the nose; reaches the brain in 8 secs
Vaginally-Through the vagina
Rectally- Through the rectum
Intrathecally-Through the spinal cord
Intrahemispherally-Through one or both of the hemispheres
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Term
| What areas are difficult for drugs to go through? |
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Definition
| The joints, spine,testicles, brain, and eyes. It can be done; but these arent the preferred methods for administering medications. |
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Term
| What is a drug's bioavailability if urine screen test states that 100% of the drug in present in the urine? |
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Definition
| The drug has 100% bioavailabilty. The drug made it through the first pass (first filtering) by the liver and was excreted through the kidneys. |
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Term
| If 100% of a drug is present in fecal matter; what was the drug's bioavailability in the body? |
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Definition
| The drug has 0% bioavailability because the liver functionalized the drug and it was excreted into the fecal matter. |
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Term
| What constitutes a drug's bioavailabilty? |
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Definition
| How much of the drug is present in the bloodstream and cleared the liver. |
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Term
| What are the drug classifications for pregnant women? |
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Definition
The drug classifications for pregnant women are A, B, C, D, and X.
It important to note that Europe treats class C drugs as class D medications and class D as class X medications when prescribing medications for pregnant women |
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Term
| What is the "cleanest" SSRI medication and why? |
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Definition
| Lexapro is the cleanest SSRI because it has the least amount of side effects. |
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Term
| What are the the pregnancy classification for antidepressants? |
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Definition
Most antidepressants are classified as C medications; however, there are several drugs that have a D and X classification and should not be given to pregnant women.
Birth defects and abnormalities have been been found with medications classified as C, D, and X. |
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