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Psychiatric Disease
Chapter 29
64
Pharmacology
Graduate
05/11/2013

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Term
Thorazine
Definition
Chlorpromazine
Low potency typical antipsychotic
100 mg of chlorpromazine is equivalent to 2 mg of haloperidol

Dosage forms: tablets, sustained release capsules, syrup, concentrate, rectal suppository, injection
Term
Mellaril
Definition
Thioriddazine
Low potency typical antipsychotic
Pigmentary retinopathy is seen at daily doses of >800 mg/d
BBWarning: QT prolongation

Dosage form: tablet, suspension, concentrate
Term
Trilafon
Definition
Perphenazine
Medium potency typical antipsychotic
Moderate sedation

Dosage form: tablets, injection
Term
Prolixin
Definition
Fluphenazine
high potency typical antipsychotic
Deconate injection every 2 weeks; immediate release injection, 5-10 mins onset

Dosage form: tablets, deconate injection, injection regular release, elixir, concentrate
Term
Haldol
Definition
Haloperidol
high potency typical antipsychotic
Deconate injection every 3 weeks; imediate release injection 5-10 min onset

Dosage forms: tablets, concentrate, deconate injection, injection regular release.
Term
Clozaril
Definition
Clozapine
atypical antipsychotic
tablet
AE: sedation, wt gain, seizure, agranulocytosis, orthostasis, myocarditis
indicated for refractory schizo only monitor WBC/ANC
Term
FazzaClo
Definition
Clozapine
atypical antipsychotic
disintegrating clozapine tablet
indicated for refractory schizo only monitor WBC/ANC
Term
Risperdal
Definition
Risperidone
atypical antipsychotic
tablets, concentrate
AE: Dose related EPS
Term
Risperdal-M
Definition
Risperidone
disintegrating risperidone tablets
Term
Risperdal Consta
Definition
Risperidone
Long acting injection
Term
Zyprexa
Definition
Olanzapine
atypical antipsychotic
Adverse effects: sedation, orthostasis, WEIGHT GAIN
Term
Zyprexa Zydis
Definition
Olanzapine
atypical antipsychotic
disintegrating olanzapine tablets
good for patints who cheek meds
Term
Zyprexa IntraMuscular
Definition
Olanzapine
atypical antipsychotic

AE: sedation, orthostasis
Term
Zyprexa Relprevv
Definition
Olanzapine
atypical antipsychotic
Extended-release IM injection
AE: post injection delirium/sedation syndrome, wt gain, EPS, dry mouth.
Term
Seroquel
Definition
Quetiapine
atypical antipsychotic
tablets
AE: sedation, dizziness, HA
Cataract risk
Term
Seroquel XR
Definition
Quetiapine
atypical antipsychotic
Extended release tablet
Term
Geodon
Definition
Ziprasidone
atypical antipsychotic
Capsules and injection
AE: qt prolongation
Term
Abilify
Definition
Aripipazole
atypical antipsychotic
tablets, concentrate, injection
AE: possible insomnia
Term
Abilify Discmelt
Definition
Aripipazole
disintegrating tablet
Term
Fanapt
Definition
Illoperidone
atypical antipsychotic
tablets
AE: dizziness, nasea, somnolence, eps, qt prolongation
Titrate dose to avoid orthostatic hypotension
Term
Saphris
Definition
Asenapine
atypical antipsychotic
Sublingual tablets
AE: EPS, insomnia, serious allergic reaction
Term
Latuda
Definition
Lurasidone
atypical antipsychotic
Tablets
AE: somnolence, nasea and vomiting, EPS (dose releated)
Take with food at least 350 calories, contraindicated with strong CYP3A4 inducers or inhibitors
Term
Lithobid
Definition
Lithium
Mood Stabilizers
Dosage forms: caplets, tablets, SR tablets, syrup
Monitor Blood levels: acute: 0.6-1.2mEq/L. Maintenance 0.8-1mEq/L
AE: tremor, polydipsia or polyuria, nasea, diarrhea, wt gain, hypothyroidism
Term
Eskalith CR
Definition
Lithium
Term
Depakote
Definition
Divalproex Sodium
mood stabilizer
tablets, ER tablets
AE: gi upset, sedation, tremor, wt gain, alopecia, transient elevation in LFTs
Term
Tegretol
Definition
Carbamazepine
mood stabilizer
tablets, chewable tablets, Er tablets,
suspension
AE: ataxia, dizziness, slurred speech, aplastic anemia
Term
Lamictal
Definition
Lamotrigine
mood stabilizer
tablets, chewable tablets
AE: dizziness, HA, ataxia, nausea, rash
Term
Nardil
Definition
Phenelzine
Monoamine Oxidase Inhibitor
tablet
Term
Parnate
Definition
Tranylcypromine
Monoamine Oxidase Inhibitors
tablet
Term
Elavil
Definition
Amitriptyline
Tricyclic Antidepressants
tablets, injection
Pregnancy category D
Term
Pamelor
Definition
Nortriptyline

Tricyclic Antidepressants
Capsules, injection
pregnancy category D
Term
Aventyl
Definition
Nortriptyline
Term
Tofranil
Definition
Imipramine

Tricyclic Antidepressants
capsule
Term
Tofranil-PM
Definition
Imipramine
tablets, injection
pregnancy category D
Term
Sinequan
Definition
Doxepin

Tricyclic Antidepressants
capsules, concentrate, cream
Pregnancy category C
Term
Norpramin
Definition
Desipramine

Tricyclic Antidepressants
tablets
pregnancy category C
Term
Celexa
Definition
Citalopram
SSRI
tablets, syrup
Max dose 40mg/d, Greater may cause QT prolongation
Term
Lexapro
Definition
Escitalopram
SSRI
tablets
S-isomer of citalopram
10mg lexapro = 40 mg celexa
Term
Luvox
Definition
Fluvoxamine
SSRI
Tablets
Term
Paxil
Definition
Paroxetine
SSRI
tablets, suspension
Max dose 50 mg/d
The least activating SSRI
Term
Paxil CR
Definition
Paroxetine
SSRI
tablets
CR formulation associated with fwer side effects
Term
Prozac
Definition
Fluoxetine
SSRI
capsule
Longer half-life, 5 week break before starting MOA-i
Term
Sarafem
Definition
Fluoxetine
SSRI
Tablet, syrup, capsule
Term
Zoloft
Definition
Sertraline
SSRI
tablets, concentrate
Term
Effexor
Definition
Venlafaxine
SNRI
capsule
Monitor BP
Term
Effexor XR
Definition
Venlafaxine
SNRI
capsule
Less GI upset with extended release
montior BP
Term
Pristiq
Definition
Desvenlafaxine
SNRI
Extended release tablets
Adjust in renal impairment <30ml/min dose every other day
monitor BP
Term
Cymbalta
Definition
Duloxetine
SNRI
capsules
Also used for diabetic peripheral neuropath,
monitor BP
Term
Xanax
Definition
Alprazolam
BZD
Term
Librium
Definition
Chlordiazepoxide
BZD
Term
Klonopin
Definition
Clonazepam
BZD
Term
Tranxene
Definition
Clorazepate
BZD
Term
Valium
Definition
Diazepam
BZD
Term
ProSom
Definition
Estazolam
BZD
Term
Dalmane
Definition
Flurazepam
BZD
Term
Paxipam
Definition
Halazepam
BZD
Term
Ativan
Definition
Lorazepam
BZD
Term
Serax
Definition
Oxazepam
BZD
Term
Centrax
Definition
Prazepam
BZD
Term
Doral
Definition
Quazepam
BZD
Term
Restoril
Definition
Temmazepam
BZD
Term
Halcion
Definition
Triazolam
BZD
Term
Which three BZDs are conjucaged and are preferred in patients with hepatic dysfunction and elderly patients?
Definition
Lorazepam, oxazepam, and temazepam
LOT
Term
Buspar
Definition
Buspirone
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