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Principles of Chemistry I: Immune system
N/A
51
Chemistry
Not Applicable
11/04/2014

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Term
Inside your body there is an
amazing protection mechanism
called the ______ ______. It is
designed to defend you against
millions of bacteria, microbes,
viruses, toxins and parasites that
would love to invade your body.
Definition
Immune System
Term
The major components of the
immune system are (there are 8):
Definition
Thymus, spleen, lymph system,
bone marrow, white blood cells,
antibodies, complement system,
hormones
Term
__________ hold up to 80% of all of
our immune function by some
sources
Definition
Intestines
Term
In your chest, between your breast bone
and your heart, is responsible for
producing T-cells (see later) early in
our lives.
Definition
Thymus
Term
The ______ filters the blood looking for
foreign cells (it also
looks for old red blood cells in need
of replacement to destroy and
recycle
Definition
Spleen
Term
What is the main function of bone marrow?
Definition
Produces new red and white blood cells.
Term
The marrow produces all blood cells from ____ _____.
Definition
Stem Cells
Term
Precursors to different cell types:
Definition
Stem Cells
Term
These blood cells are fully formed in the bone marrow, and enter the blood stream fully formed.
Definition
Red Blood Cells
Term
These blood cells are produced in the bone marrow, but mature elsewhere.
Definition
White Blood Cells
Term
Lymph is blood plasma. What is blood plasma?
Definition
The liquid that makes up blood minus the red and white blood cells.
Term
Random bacteria that enter the body eventually end up in this fluid.
Definition
Lymph
Term
The cells also produce proteins and waste products and the _____ absorbs these products and carries them away.
Definition
Lymph
Term
One job of the _____ ______ is to drain and filter these fluids to detect and remove the bacteria.
Definition
Lymph System
Term
How is lymph moved throughout the body? Hint: its not pumped.
Definition
Lymph is not pumped through
the body like blood, but instead is “pushed”
through the lymph system as the vessels are
compressed by surrounding muscles
Term
Lymph eventually drains into the Left and Right __________ veins.
Definition
Subclavian
Term
__________ are also referred to as immuno-globulins and gamma-globulins
Definition
Antibodies
Term
Antibodies are produced by _____ _____ _____.
Definition
White Blood Cells (specifically, the differentiated form of a B-cell known as a plasma cell)
Term
What shape, in general, are antibodies?
Definition
Y-shaped
Term
They are Y-shaped proteins that each respond to a ________ _______ (bacteria, virus or toxin) and are ADAPTIVE.
Definition
Specific Antigen
Term
When an antibody binds to a toxin, it is called a/an _________.
Definition
Antitoxin
Term
When an antibody binds to a venom, it is called a/an _________.
Definition
Antivenom
Term
The binding of an antibody to a toxin generally enables/disables the chemical action of the
toxin
Definition
Disables
Term
When an antibody binds to the outer coat of a virus particle or the cell wall of a bacterium it can facilitate/stop their movement through cell walls.
Definition
Stop
Term
A large number of antibodies can bind to an invader and signal to the __________ ______ that the invader needs to be removed.
Definition
Compliment System
Term
What are the 5 classes of Antibodies?
Definition
IgG, IgM, IgA, IgE, IgD
Term
Which classes of antibodies are monomers? There are 3.
Definition
IgD, IgE, IgG
Term
Which class of antibody is a dimer? There is only one.
Definition
IgA
Term
Which class of antibody is a pentamer? There is only one.
Definition
IgM
Term
Which antibody is the most common in the body, making up roughly 70-75% of the antibodies?
Definition
IgG
Term
Which antibody is typically found in bodily secretions, such as sweat, breast milk, and mucous of the respiratory and gastrointestinal systems?
Definition
IgA
Term
This type of antibody causes the release of histamine in response to an allergy. It also protects against parasitic worms.
Definition
IgE
Term
This antibody is the only one that crosses the placenta, and therefore, the only antibody that provides passive immunity to the fetus.
Definition
IgG
Term
There are only a handful of proteins
in the __________ ______, which float freely in your blood, that
assist the antibodies in a less specific fashion
Definition
Compliment System
Term
Complements are manufactured in the _____.
Definition
Liver
Term
Compliment causes the ________ of cells.
Definition
Bursting/Lysing
Term
There are several ________ generated by components of the immune system.
Definition
Hormones
Term
Steroids and corticosteroids (components of
adrenaline) ________ the immune system.
Definition
Suppress
Term
_______ is a hormone that
encourages lymphocyte production (a lymphocyte is a form of
white blood cell - see below).
Definition
Thymosin
Term
Name 4 Surface barriers to microorganism attack:
Definition
- Skin
– Mucus in nasal passages and lungs
– Lysozyme in the tears of eyes
– HCl (low pH) in the stomach
Term
What are the two different types of immunity?
Definition
Innate and Adaptive
Term
A hypersensitivity reaction is also known as?
Definition
Allergic Reaction
Term
Which antibody is most closely associated with hypersensitivity reactions?
Definition
IgE
Term
Hyperseneitivity reactions can be severe: closing airways, blood pressure drops, and circulatory collapse occur as this type of shock sets in:
Definition
anaphylactic shock
Term
Are hypersensitivities (allergies) permanent, or can it be lost eventually?
Definition
In theory, people can overcome, or become desensitized to, allergies.
Term
What is immune incompetence?
Definition
The immune system stops working
Term
Which type of disease is characterized by the immune system no longer recognizing its own cells and
starting to attack them?
Definition
Autoimmune Disease
Term
Rheumatoid arthritis and Lupus are two of this type of disease:
Definition
Autoimmune disease
Term
These stimulate antibody production, which can last for years.
Definition
Vaccinations
Term
What are the 4 types of vaccinations?
Definition
1. Live attenuated (weakened) virus or bacterial for virus protection
2. Inactive (killed) bacteria or virus
3. Toxiods (poisons) that kill bacteria
4. Component systems (part of a virus or bacteria)
Term
Why are diseases such as cholera and influenza not easily controlled by vaccinations?
Definition
These types of diseases mutate easily. Vaccines typically only control one form of the disease, meaning that when the disease mutates, it can mutate into a form of the disease that is not controlled by the vaccine.
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