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Principles of Chemistry II: Fluids
N/A
63
Chemistry
Undergraduate 1
11/04/2014

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Term
The body needs a
continuous supply of the
gas ___ (not cut off for more
than minutes) and it is
simultaneously trying to rid
itself of excess amounts of
the gas ___.
Definition
O2 (Oxygen), CO2 (Carbon Dioxide)
Term
Pressure =
Definition
Force/Area (Force divided by Area)
Term
One unit of measure for pressure is the Pascal (Pa), which is defined as:
Definition
1 Newton (N) of pressure acting on one square meter
Term
Which unit is blood pressure measured in?
Definition
mm Hg; millimeters of mercury
Term
Gas cylinders and Car tire pressure is typically measured in:
Definition
psi - pounds per square inch
Term
The earth has pressure from
all of the air above it that is
referred to as the ___________ ________ and is equal to about
760mm of Hg lifted up a
column
Definition
atmospheric pressure
Term
The greater the area over which
a force acts, the greater/less pressure it
exerts?
Definition
less
Term
In a clinical setting, we use ___
pressure (vacuum) and ____
pressure (pushing) to fill and
empty a hypodermic syringe.
Definition
low, high
Term
Since liquids flow to fill their containers,
pressure on them is equally exerted in all
directions and pressure is transmitted
equally to every part of the liquid. What is this principle called?
Definition
Pascal's Principle
Term
The pressure exerted by a column of
liquid is proportional to:
Definition
– the height of a column
– the liquid density (toothpaste vs. water)
Term
If a blood vessel has a weak spot in it, Pascal’s principle
would suggest that this is where pressure would be relieved
with a burst. Fluids flow down a pressure gradient-FROM
high pressure TOWARDS low pressure. If the blood vessel doesn't burst, but instead balloons, this balloon is known as:
Definition
an aneurysm
Term
The pressure in the aorta is around __ - ___mmHg
Definition
90 - 100 mmHg
Term
The pressure in the right atrium is about ___ mmHg
Definition
0 mmHg
Term
The difference in pressure between the higher pressure in the aorta and the lower pressure in the right atrium is due to:
Definition
resistance
Term
The viscosity of blood is about ___x - ___x that of water
Definition
3x-4x the viscosity of water
Term
If one were to extract all of the blood vessels int he body and lay them end to end, how long would they stretch?
Definition
60,000 miles
Term
We know that the diameter of the blood vessel plays a part in how fast the fluid flows through it. Given equal relative pressures, would you expect the blood to flow faster in a blood vessel with a larger or smaller diameter?
Definition
The blood would flow faster in a smaller diameter blood vessel.
Term
What is considered normal blood pressure?
Definition
120/80 mmHg
Term
What is the name of the tool used to measure blood pressure?
Definition
Sphygmomanometer
Term
Would you expect blood pressure to be higher at the top of the body (the head) or at the bottom of the body (the feet)?
Definition
Due to hydrostatic effects, the blood pressure in the feet is much higher than that in the head. Typically, when the pressure at heart level is at 90 mmHg, the pressure in the head is around 53 mmHg, and the pressure in the feet is around 202 mmHg.
Term
These blood vessels have the highest blood pressure outside of the heart:
Definition
Arteries
Term
These blood vessels move blood away from the heart.
Definition
Arteries
Term
These blood vessels have one of the lowest percent
volumes of liquid flow per unit area.
Definition
Arteries
Term
These blood vessels move blood towards the heart.
Definition
Veins
Term
These blood vessels have the highest surface area.
Definition
Capillaries
Term
When using an IV delivery system, what two factors affect the rate of flow?
Definition
Height of the IV bag, and viscosity of the IV fluid. For most IVs, however, the viscosity is similar. In these cases, only height matters for determining rate of flow.
Term
What is systolic blood pressure?
Definition
Pressure when the heart is contracting
Term
What is diastolic blood pressure?
Definition
Pressure when the heart is relaxed
Term
Clinically, high blood pressure is defined as blood pressure higher than __/__.
Definition
140/90
Term
Nervousness in the doctors office is a common occurrence, often referred to as "Whitecoat Syndrome." This can _______ blood pressure, leading to false readings.
Definition
Elevate
Term
Blood Pressure is a complex function of the balance of sodium,
potassium, magnesium, calcium, water, etc. in ones blood.

Increasing Water, Magnesium, and Potassium tend to ________ blood pressure.
Definition
Decrease
Term
Blood pressure, especially systolic blood pressure, tends to ________ with age.
Definition
Increase
Term
Someone dies from heart disease every __ seconds.
Definition
34
Term
More people die from _____ _______ than any other cause.
Definition
Heart Disease
Term
What is Angina
Definition
Decreased oxygen getting to the heart
Term
Angina, High Blood Pressure, Thromboses, Strokes, and Heart attacks are all versions of _____ _______
Definition
Heart Disease
Term
There are four types of drugs to lower blood pressure. What are they?
Definition
1. Diuretics
2. beta-blockers,
3. calcium channel blockers,
4. nitro-vasodilators
Term
What are some side effects of drugs used to treat high blood pressure?
Definition
kidney damage, fatigue, muscle cramping, faintness,
increase in gallstones, dry persistent cough, headache, diarrhea, loss of taste,
nausea, dizziness, skin rashes, irregular heartbeats, nervousness, numbness,
fever and chills, stomach pain, cold extremities, constipation, etc.
Term
What are some natural alternatives to blood pressure-lowering drugs?
Definition
Reduction in alcohol intake, regular exercise, eating foods, nutrients, and spices that are known to reduce blood pressure, etc
Term
What is Boyle's Law?
Definition
Boyle's law describes the relationship between the volume and pressure of a gas; the two are inversely related. Therefore, when volume is increased, pressure is decreased. When volume is decreased, pressure is increased.
Term
How does air enter the lungs?
Definition
The lungs expand, causing a partial vacuum within the lungs (increased volume = decreased pressure). This partial vacuum causes air to flow into the lungs.

Note: The lungs themselves contain no muscles. In order for the lungs to expand, the diaphragm contracts, increasing the volume of the thoracic cavity. This causes the lungs to expand (once again, increase in volume = decrease in pressure). The expansion of the lungs causes a partial vacuum within the lungs, as described above, causing air to flow into the lungs.
Term
How does air leave the lungs?
Definition
The lungs contract, causing higher pressure inside the lungs than outside the body. This forces excess air out until the pressures inside the lungs and outside the body are equalized.

Note: Once again, this is mostly driven by the diaphragm. However, in the case of normal breathing, no effort is needed because in order to force air out, the diaphragm simply relaxes. This causes an excess in pressure in the thoracic cavity, forcing air out of the lungs.
Term
What is tidal volume? How much air is moved?
Definition
Tidal volume is the normal amount of air typically breathed in and out. This is around 450 mL.
Term
What is the Inspiratory reserve volume?
Definition
Extra amount of air taken in with deep breathing, ~3600mL
Term
What is Expiratory reserve volume?
Definition
Extra amount of air forced out, ~1200mL
Term
What is the Vital Capacity?
Definition
The vital capacity is the sum of the tidal volume, the inspiratory reserve volume, and the expiratory reserve volume.
Term
What is the Residual Volume?
Definition
Extra volume of air left in lungs after forced strongest possible expiration
Term
What is the total lung capacity?
Definition
Sum of vital capacity and residual volume, ~6000-6500mL
Term
What is Henry's Law?
Definition
Henry's Lay states that the Solubility of a gas in a liquid depends on the partial pressure of the gas and its solubility coefficient (SC). A higher SC means it would be more soluble.
Term
Carbon Dioxide, CO2, is how many more times soluble in water than Oxygen, O2?
Definition
23x
Term
What is the carrier protein used to transport Oxygen in the blood?
Definition
Hemoglobin
Term
Which term is used to indicate the Hemoglobin has as many oxygens bound to it as it can carry?
Definition
Saturated. When Hemoglobin is saturated, it has the maximum of 4 oxygen molecules bound to it.
Term
Arterial blood is normally __% to ___% saturated
Definition
98% to 100& saturated
Term
Which device is used to determine the percent saturation of blood?
Definition
A Pulse Oximeter
Term
How do partial pressures work?
Definition
All of the pressures of each individual gas are summed to give the total pressure of a system.
Term
The partial pressures of nitrogen and oxygen are 0.8 and 0.2 atm, respectively, summing to 1 atm total. At 99 feet below the sea level, these partial pressures have increased to 3.2 and 0.8 atm, respectively, summing to what total pressure exerted on the body?
Definition
4 atmospheres.
Term
As a diver dives deeper beneath the sea, the partial pressure of nitrogen increases to levels that are no longer safe in the body. ________ ________ results when the increased levels of nitrogen dilute the oxygen levels in the body.
Definition
Nitrogen Narcosis
Term
What is nitrogen narcosis?
Definition
Nitrogen narcosis occurs when nitrogen dilutes the amount of oxygen in the body, as can happen with divers. Nitrogen narcosis affects the nervous system.
Term
What are symptoms of Nitrogen Narcosis?
Definition
Impaired judgment, loss of
short-term memory, slowed response time, and
sometimes euphoria
Term
What are "the bends"?
Definition
The bends come from too rapid of a depressurization. For example, when a diver surfaces too quickly after diving, the gases, specifically the nitrogen in the blood, expands too rapidly within the blood vessels, causing what is known as "the bends."
Term
What are symptoms of "the bends"?
Definition
fatigue, mild to
severe pain in the joints, rashes or itchy
patches, dizziness, nausea,
disorientation, numbness, mild to severe
paralysis, loss of vision or hearing,
unconsciousness, and even death.
Term
What is a Venturi Mask? What is it used for?
Definition
A Venturi Mask contains a valve that only allows oxygen in and carbon dioxide out. It provides an oxygen rich atmosphere for oxygen therapy.
Term
What is the purpose of a nebulizer?
Definition
A nebulizer is a device that breaks up large liquid drops into smaller ones and disperses
them in gas (air). It is used to carry liquids directly into the lungs.
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