Shared Flashcard Set

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Preventive Dentistry
Oral cancer chapter 7 from book
20
Dentistry
Undergraduate 3
09/23/2013

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Cards

Term
How long is the oral cancer patient at risk for developing osteoradionecrosis?
Definition
for a lifetime
Term
mucositis is a concern for patients who have what treatment types?
Definition
radiation therapy or chemotherapy
Term
the population most likely to die from oral cancer is?
Definition
african american males
Term
the most common area for intraoral squamous cell carcinoma to occur is ?
Definition
lateral borders of the tongue
Term
squamous cell carcinoma accounts for what % of oral and oropharyngeal cancers?
Definition
90%
Term
what are some possible signs of cancer?
Definition

mucosal ulcerations that are still present after 2 weeks

red or white patchy lesions

persistant pain

lumps or thickening of soft tissue

sore throat

painful chewing or swallowing

numbness

loss of teeth

change in voice

ear pain no hearing loss

trismus (difficulty opening mouth)

neck mass

Term
neoplasm
Definition
new growth
Term
proliferation
Definition
rapid growth exceeding normal growth patterns (a bunch of new cells)
Term
carcinomas
Definition
malignant neoplasms, cells look abnormal and act abnormal
Term
epithelial dysplasia
Definition
pre malignant changes in size, shape number, nuclei, increased mitosis (cell division)
Term
apoptosis
Definition
programmed cell death, removal of aging cells or damaged DNA from body
Term
what cell functions must be disrupted for cancer to occur?
Definition

-growth regulation

-apoptosis

-differentiation

-replicative senescence

-angiogenesis

-DNA repair

-tissue remodeling and migration

-immune evasion

Term
growth regulation
Definition
proliferation (bunch of new cells) beyond normal number expected in cell division
Term
differentiation
Definition
degree of alteration cells from their normal morphology
Term
replicative senescence
Definition
irreversible loss of cells ability to stop dividing
Term
angiogenesis
Definition
buildup of vascular tissue needed to sustain cancer growth
Term
DNA repair
Definition
a cell monitors and repairs DNA disruption before replication to avoid passing faulty DNA to new cells
Term
tissue remodeling and migration
Definition
ability to travel beyond normal borders of tissue
Term
immune evasion
Definition
breakdown in ability to monitor tissues for evidence of cancer
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