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Prelim 1 Chapter CHF Three
Vocabulary
31
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Undergraduate 1
09/22/2012

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Term
chromosome
Definition
one of the 46 molecules of DNA (in 23 pairs) that each cell of the human body contains and that, together, contain all the genes. Other species have more or fewer chromosomes
Term
deoxyribonucleic acid (DNA)
Definition
The molecule that contains the chemical instructions for cells to manufacture various proteins
Term
gene
Definition
a section of a chromosome and teh basic unit for the trasmission of heredity, consisting of a string of chemicals that are instructions for the cell to manufacture certain proteins
Term
allele
Definition
any of the possible forms in which a gene for a particular trait can occur
Term
genome
Definition
the full set of genes that are the instructions to make an individual member of a certain species
Term
gamete
Definition
a reproductive cell; that is, a sperm or ovum that can produce a new individual if it combines with a gamete from the other sex to make a zygote
Term
zygote
Definition
the single cell formed from the fusing of two gametes, a sperm and an ovum
Term
genotype
Definition
an organism's entire genetic inheritance, or genetic potential
Term
23rd pair
Definition
the chromosome pair that, in humans, determines the zygote's (and hence the person's) sex. The other 22 pairs are autosomes, the same whether the 23rd pair is for a male or a female
Term
XX
Definition
female
Term
XY
Definition
male
Term
monozygotic (MZ) twins
Definition
twins originating from one zygote that splits apart early in development (identical twins)

triplets, quadruplets can occur as well
Term
dizygotic (DZ) twins
Definition
twins who are formed when two separate ova are fertilized by two separate sperm around the same time (fraternal twins)
Term
infertility
Definition
inability to conceive after at least a year of trying to do so via sexual intercourse
Term
assisted reproductive technology (ART)
Definition
general term for the techniques designed to help infertile couples conceive and then sustain a pregnancy
Term
in vitro fertilization (IVF)
Definition
Fertilization that takes place outside a woman's body (as in a glass laboratory dish). The procedure involves mixing sperm with ova that have been surgically removed from the woman's ovary. If the combination produces a zygote, it is inserted into the woman's uterus, where it may implant and develop into a baby
Term
phenotype
Definition
what one sees/genetic expression

personality, appearance
Term
polygenic
Definition
interaction of many genes
Term
multifactorial
Definition
interaction of several genetic and environmental variables
Term
Human Genome Project
Definition
An international effort to map the complete human genetic code. This effort was essentially completed in 2001, though analysis is ongoing
Term
additive gene
Definition
genes from each parent make active contribution to phenotype (skin color; height)
Term
dominant-recessive pattern
Definition
the interaction of a pair of alleles in such a way that the phenotype reveals the influence of one allele (the dominant gene) more than that of the other (the recessive gene)
Term
carrier
Definition
A person whose genotype includes a gene that is not expressed in the phenotype.
Term
X-linked
Definition
genes carried on the X chromosome
ex. If a boy inherits an X-linked recessive trait from his mother, he expressed that trait because the Y from his father has no counteracting gene. Girls are less likely to express them.
Term
heritability
Definition
a statistic that indicates what percentage of the variation in a particular trait within a particular population, in a particular context and era, can be traced to genes
Term
mosaicism
Definition
a condition in which an organism has a mixture of cells, some normal and some with an odd number of chromosomes or a series of missing genes
Term
Down syndrome
Definition
a condition in which a person has 47 chromosomes

three chromosomes at the 21st position

typically have distinctive characteristics, including unusual facial features, heart abnormalities, and language difficulties

also called trisomy-21
Term
fragile X syndrome
Definition
A genetic disorder in which part of the X chromosome seems to be attached to the rest of it by a very thin string of molecules. The cause is a single gene that has more than 200 repetitions of one triplet.
Term
genetic counseling
Definition
Consultation and testing by trained experts that enable individuals to learn about their genetic heritage, including harmful conditions that they might pass along to any children they may conceive.
Term
phenylketonuria (PKU)
Definition
A genetic disorder in which a child's body is unable to metabolize an amino acid called phenylalanine. The resulting buildup of phenylalanine in body fluids causes brain damage, progressive mental retardation, and other symptoms.
Term
clones
Definition
result from removing a cell from a living organism and creating a second genetically-identical organism from this cell
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