Term
| Indications for Beta Blockers |
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Definition
1. HTN
2. IHD/Angina
3. CHF
4. Migraine Headaches
5. Secondary prevention post MI |
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Term
| Contraindications for Beta Blockers |
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Definition
1. Cardiogenic Shock
2. Sinus Bradycardia
3. Do not initiate BB in decompensated CHF |
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Term
| Precautions for Beta Blockers |
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Definition
1. Asthma/Bronchospastic disease (unless non-specific agent, then it is a CI)
2. Diabetes Mellitus (masks hypoglycemia)
3. If need to DC, titrate off over 1-2 weeks (rebound HTN)
4. Titrate up slowly to avoid aggravating sx, taking off titrate down.
5. "Don't just stop taking beta blocker suddenly" |
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Term
| Class drug interactions with Beta Blockers |
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Definition
1. Verapamil (review effects 'AV block' 'decreased HR')
2. Clonidine
3. NSAIDs
know how to manage these interactions (if pt. is on both, figure out how to take which ones off) |
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Term
| Cardioselective beta-blockers |
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Definition
1.bisoprolol
2. atenolol
3. metoprolol |
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Term
| non-cardio-selective beta blockers |
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Definition
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Term
| Class ADR of Beta Blockers |
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Definition
1. decreased HR
2. beta blockade in pulmonary symptoms
3. cardioselectivity is lost at higher doses |
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Term
| Pt. counseling for beta blockers |
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Definition
1. do not stop medicine abruptly
2. may cause fatigue (lowered HR)
3. something else she said |
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Term
|
Definition
| Tenormin I: HTN (25-100mg daily), angina (50-200mg daily), acute MI Pharmacology: relatively cardioselective does not cross BBB (may help with depression effect of bb's) |
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Term
| atenolol w/ chlorthalidone |
|
Definition
Tenoretic I: HTN has diuretic CI: sulfonamide allergy
1 tab daily (50/25, 100/25) |
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|
Term
|
Definition
Lopressor I: HTN< post MI infaction, angina Pharmacology: relatively cardioselective, crosses BBB counseling: food can increase absorption of drug
50mg bid |
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Term
|
Definition
| Toprol XL I: HTN (50-100mg daily), angina pectoris (100mg qd), stable NHYA II or II HF (12.5-200mg daily) Pharmacology: relatively cardioselective, crosses BBB Pt. counseling: CHF - counsel pts. to monitor for increasing sx, (weight gain, SOB) take with foo to increase absorption, do not crush tabs |
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Term
|
Definition
Trandate/Normodyne HTN Pharmacology: Alpha 1 adrenergic blocker, non-selective beta blocker
200mg bid |
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Term
|
Definition
Zebeta I: HTN Pharmacol: relatively cardioselective effective but NOT approved for CHF
5mg daily |
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|
Term
|
Definition
Ziac
I: HTN
Pharm: combo product- relatively cardioselective, thiazide diuretic
CI: Sulfonamide allergy
Pt. counseling: take in AM, photosensitivity (from diuretic) |
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Term
|
Definition
Coreg
I: 1. HTN (start 6.25 BID)
2. CHF (start 3.125 BID)
Pharm: nonselective BB w/ alpha 1 block activity
Pt counseling: take with food to decrease orthostatic hypotension (reduces spike)
titrate q 2 weeks |
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Term
Which beta blocker would be best choice for a pt. with asthma?
1. atenolol
2. carvedilol
3. labetolol
4. propranolol |
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Definition
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|
Term
Which beta blocker would be the best choice for a patient with CHF and asthma?
1. atenolol
2. bisprolol
3. carvedilol
4. metoprolol |
|
Definition
| Answer: Metoprolol (would have to be XL) |
|
|
Term
Which beta blocker would you expect to cause least CNS side-effects?
1. Atenolol
2. Metoprolol
3. Propranolol |
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Definition
| Answer: atenolol (does not cross BBB) |
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|
Term
|
Definition
1. HTN
2. Diabetic Neuropathy
3. Reduction in future CV events
4. Reduction in cardiac events post MI
5. HF |
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Term
| ACE Inhibitor class precautions |
|
Definition
1. pregnancy (category D) (2nd or 3rd trimester)
2. pts. with impaired renal fx
- must use caution, low, initial dosing, and monitoring
3. pts. currently on aggressive diuretic therapy, NSAID therapy, and/or with CHF
-higher risk of acute renal failure upon initiation or dose increase |
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Term
| ACE Inhibitor Class Adverse Effects |
|
Definition
1. Cough
2. Dizziness
3. Orthostatic Effects
4. Hyperkalemia
5. Decreased CrCl
6. Rash (rare event) |
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Term
| ACE Inhibitor pt. consultation points |
|
Definition
1. Orthostatic counseling
2. Report facial swelling/difficulty breathing (angioedema)
3. Avoid potassium supplements unless directed
4. Avoid concomitant antacids within 1-2 hours |
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Term
| ACE Inhibitor class drug interactions |
|
Definition
1. Potassium supplements and sparing diuretics
2. NSAID therapy (decrease ACEI effect)
3. Alteration of Lithium levels |
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Term
| NSAIDs dilate or constrict afferent arterioles of glomerulus? |
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Definition
| constrict afferent. (blocking prostaglandin which dilates) |
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Term
| What two ACE's are more sensitive to interactions (antacids, foods, etc) and should be taken on an empty stomach |
|
Definition
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|
Term
|
Definition
Accupril I: HTN (Lower dosage when using diuretics) -adjunct in tx of CHF -requires adjustment for renal dysfx
20-80mg daily |
|
|
Term
|
Definition
Captopril
I: HTN
Dose: 25 mg TID
Counseling: take one hour before meals
ADR: taste disturbances
May be DOC for pt. who need to be on a shorter acting ACE |
|
|
Term
|
Definition
Lotensin
I: HTN
Dose: 10-80 mg/day |
|
|
Term
|
Definition
Lotensin HCT
I: HTN
- not indicated for initial therapy
Dose: 1 tab daily
CI: sulfonamide allergy |
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|
Term
|
Definition
Mavik
I: HTN
Dose: 2-4 mg/day |
|
|
Term
|
Definition
Monopril
I: CHF adjunct (10-40 mg/day)
-HTN (20-80 mg/day) |
|
|
Term
|
Definition
Univasc
I: HTN
Dose: (7.5-30 mg/day)
take on an empty stomach |
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|
Term
|
Definition
Vasotec
I: CHF (2.5-20 mg BID)
-HTN (10-40 mg daily)
IV form FDA indication: HTN |
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|
Term
|
Definition
Vaseretic
I: HTN
Dose: 1-2 tabs daily
Combo not indicated for initial tx of HTN |
|
|
Term
|
Definition
Zestril or Prinivil
IL CHF (5-40 mg daily) (target 20-40 qd)
-HTN (5-40 mg daily) |
|
|
Term
|
Definition
Zestoretic
I: HTN
Dose: 10/12.5 - 20/25 daily
CI: sulfonamide allergy
Counsel: take early in AM, photosensitivity
Combo not indicated for initial treatment of HTN |
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|
Term
|
Definition
Atacand
I: HTN
8-32 mg daily
adjust dose for moderate hepatic impairment |
|
|
Term
|
Definition
Avapro
I: HTN
Dose 150-300 mg daily |
|
|
Term
|
Definition
Avalide
HTN (150/12.5-300/12.5mg daily)
not indicated for initial treatment
Take in the morning |
|
|
Term
|
Definition
Cozaar
HTN/diabetic neuropathy
25-100mg daily
consider low doses in hepatic impairment and volume depleted pts |
|
|
Term
|
Definition
Hyzaar
HTN
50/12.5-100/25 daily
take in the morning |
|
|
Term
|
Definition
Diovan
HTN (80-320mg daily), CHF (40-160 mg bid) |
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|
Term
|
Definition
Diovan- HCT
HTN
1 tab daily |
|
|
Term
|
Definition
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|
Term
|
Definition
Benicar HCT
HTN
1 tab daily |
|
|
Term
|
Definition
Micardis
HTN
20-80mg daily |
|
|
Term
| azilsartan + chlorthalidone |
|
Definition
Edarbyclor
HTN
1 tab daily (40/12.5 & 40/25mg tabs) |
|
|
Term
|
Definition
Tekturna
HTN
150-300mg daily |
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