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Population Genetics - Lecture 5-8
a
16
Biology
Undergraduate 3
01/17/2018

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Term
What would make a population structured?
Definition
Geographical distances, behavioural factors
Term
What effect does gene flow have on variation?
Definition
It homogenises it
Term
What is the island model?
Definition
One mainland, migration from mainland to islands
Term
What is the Deme model?
Definition
Multiple demes, migration between them
Term
If Demes were put together for analysis, what would you see, and what would this be due to?
Definition
Excess of homozygotes or deficiency of heterozygotes, Wahlund effect
Term
How can you tell the Wahlund effect apart from inbreeding?
Definition
Inbreeding should effect all loci equally, Wahlund will only effect some
Term
What is the direct method of measuring gene flow?
Definition
Following tagged individuals for estimates of migration
Term
What is the indirect method of measuring gene flow?
Definition
Use genetic markers and infer historic gene flow
Term
What is Fst?
Definition
The measure of allele frequence divergence between subpop inbreeding due to differentiation relative to total population
0=no differentiation
>0.2 = strong differentiation
Term
What is Fis?
Definition
Measure of departure from HW proportions within local subpops
0=none
positive=deficiency of heterozy
negative = excess of heterozygotes
Term
What is Fit?
Definition
measure of overall departure form HW prop in whole pop due to non-random mating within local pop (Fis) and allele freq divergence among subpops (Fst)
0 =no deviation
pos = deviation due to hetero deficient in TP
neg= due to excess of heteros in TP).
Term
How can you estimate Fst?
Definition
Fst = var(p)/mean of p (1-mean of p)
The mean reduction in heterozygosity (H) of subpop is relative to the total pop and due to genetic drift among subpops so: Fst = Ht-Hs/Ht
Term
How can heterozygote advantage maintain genetic variability?
Definition
If it becomes too common, less heterozygotes, loses advantage
Term
What are examples of frequency dependent selection where the rare morph has the advantage?
Definition
Batesian mimicry, Plant self incompatibility, predator/prey?
Term
What is an example of frequency dependent selection where the common morph has the advantage?
Definition
Poisonous butterflies - more common morph has advantage, predators more likely to have already encountered it
Term
What is an ESS?
Definition
A strategy that no previously rare strategy can invade
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