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Pneumonia
Clinical Medicine Module 4
111
Medical
Graduate
06/24/2009

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Term
What is the leading cause of death in the us due to infections?
Definition
pneumonia
Term
What is the 6th leading cause of death in the us?
Definition
pneumonia
Term
(where the infection has invaded an area. it has filtrated into an area of tissue)
Definition
infiltrate
Term
(infection has filled an area of tissue)
Definition
consolidation
Term
A confused 62 year old gentleman with a hx of alcoholism, smoking and copd presents w/ a respiratory rate of 35/min, a blood pressure of 88/58, and a bun of 35. This pt has risk factors for what illness?
Definition
pneumonia: risk factors
Term
Within what time frame of admittance is pneumonia considered cap vs. nosocomial?
Definition
w/in 48 hrs of admission = cap
Term
Cystic fibrosis, copd, and smoking are risk factors for what illness?
Definition
pneumonia
Term
What are 4 organisms that cause typical pneumonia?
Definition
strep, pneumococcus, haemophils, staph
Term
What is the most common atypical bacteria? What are 2 other orgs that cause atypical pneumonia?
Definition
mycoplasma (prevalent)= most common. also legionella, chlamydia (both rare)
Term
The following organisms cause pneumonia in what population: s. pneumoniae, h. influenzae, mycoplasma?
Definition
young healthy adult
Term
The following organisms cause pneumonia in what population: s. pneumo, h. flu, s. aureus?
Definition
elderly
Term
The following organisms cause pneumonia in what population: h. flu, s. pneumoniae, anaerobes (wide mixture)?
Definition
debilitated (asthma, smoking, copd, alcoholism)
Term
The following organisms cause pneumonia in what population: p. aerugionsa, e.coli, s. aureus?
Definition
hospitalized (nosocomial)
Term
With what pathology would a pt likely present w/pneumonia due to the following organisms: k.pneumoniae, anaerobes, m.catharrhalis?
Definition
alcoholism
Term
With what pathology would a pt likely present w/pneumonia due to the following organisms: k. pneumoniae, h.flu, s.pneumoniae, ,s.aureus?
Definition
diabetes mellitus
Term
HIV pts present more frequently with which pneumonia: p.jiroveci (pcp) or s. pneumoniae?
Definition
s.pneumoniae
Term
With what pathology would a pt likely present w/pneumonia due to the following organisms: s.pneumoniae, h.flu?
Definition
sickle cell
Term
With what pathology would a pt likely present w/pneumonia due to the following organisms: s.pneumoniae, h.flu, m.catarrhalis?
Definition
chronic lung disease
Term
With what pathology would a pt likely present w/pneumonia due to the following organisms: s.pneumoniae, h.flu?
Definition
chronic renal failure
Term
With what pathology would a pt likely present w/pneumonia due to the following organisms: p.jiroveci, s.pneumo, h.flu, cryptococcus?
Definition
hiv/aids
Term
What is the most common cause of pneumonia?
Definition
s.pneumoniae
Term
What percent of individuals carry s.pneumoniae in their nasal passsages?
Definition
50%
Term
What may influence pneumonia-causing organism's ability to increase it's affinity in the tissue?
Definition
strong association w/viral illness
Term
What is the most common reason for nosocomial pneumonia?
Definition
aspiration
Term
Once aerosolized, pneumonia-causing organisms invade which cells?
Definition
type h alveolar cells and then multiplies
Term
What follows inflammation due to pneumonia-causing organisms in lungs?
Definition
inflammation occurs and thus consolidation
Term
What type of bacteria tend to deteriorate the tissue? What potential does this entail?
Definition
atypical bacteria have the ability to injure the cilia
Term
Which type of bacteria tend to be immune mediated and have the ability to spread across lung boundaries? What characteristic of this type of pneumonia is explained by this mechanism?
Definition
atypical pneumonia. this is why atypical pneumonia effects multiple lobes
Term
Why might pneumonia pts experience pain?
Definition
referred pain from consolidation
Term
Why might you inspect pneumonia pt's head/neck?
Definition
alcoholism: teeth decay? dehydration- are the mucous membranes moist? is the neck supple?
Term
Besides the most common reason of aspiration, what might cause pneumonia?
Definition
colonization of bacteria in the nasopharynx and stomach
Term
Advanced age, malnutrition, altered level of consciousness, swallowing disorders, prolonged endotracheal intubation all are risk factors for what illness?
Definition
pneumonia
Term
What might present in a cardiac pe in a pt w/pneumonia?
Definition
hypotension leads to change in blood viscosity, leading to murmurs. (this can also occur w/anemia). also look for rate, rhythm
Term
A pt. presents w/ a fever of 101, cough w/o sputum, sweats, rigors, chills, aching muscles, headache, stomach ache, and chest pain. What might the pt have?
Definition
pneumonia
Term
Why examine a pneumonia pt's chest?
Definition
check for pathologies you might have missed
Term
What might you look for in a pneumonia pt's pe of lower extremity?
Definition
edema, distal pulses, profusion, adequate volume, clubbing, cyanosis
Term
What is the most important aspect of an exam on pneumonia pt?
Definition
*vital signs, vital signs, vital signs*
Term
What is the o2 sat level that causes concern?
Definition
below 92
Term
A pe on a pneumonia pt should inlude what 6 areas?
Definition
head and neck. cardiac. lung. abdominal. lower extremities. remember vital signs!
Term
what labs should be ordered for pneumonia?
Definition
sputum gram stain w/culture and sensitivity. are you going to wait to see what culture and sensitivity come back on? (no- tx empirically- get blood cultures before 4 hrs, then sart tx) blood cultures- (kids, some hospitals is standing protocol, co-morbity lending to sepsis). cbc, bmp, hfp, cd4 and viral loads, cardiac enzymes
Term
What are you looking for on cbc in pneumonia?
Definition
expected elevated wbc's 1st, bandemia- body is building up a defense quickly to pour out more wbc's to fight infection- left shift, anything that indicates an acute inflammatory infection. (hgb and hct to make sure pt hasn't become anemic) (or indication of another problem)
Term
What are you looking for on bmp in pneumonia?
Definition
electrolytes: adequate equilibration. most important: renal function, bun, creatinine- greater risk. if not, why? dehydration? renal insufficiency/failure in hx? glucose is important- how well is diabetes managed?
Term
What are you looking for on hepatic function panel in pneumonia?
Definition
make sure they're not having hepatic impairment if you give drug metabolized in liver (also co-moribities in liver)
Term
When would you order cardiac enzymes in pneumonia pt?
Definition
risk factor/history of heart disease. if pneumonia causes hypoxia, less o2 to heart, illness increases 02 demands- causes ischemia
Term
The following silhouette indicates which lobe/segment on a cxr: R diaphragm?
Definition
RLL/basal segment
Term
The following silhouette indicates which lobe/segment on a cxr: R heart margin?
Definition
RML/medial segments
Term
The following silhouette indicates which lobe/segment on a cxr: ascending aorta?
Definition
RUL/anterior segment
Term
The following silhouette indicates which lobe/segment on a cxr: aortic knob?
Definition
LUL/Posterior segment
Term
The following silhouette indicates which lobe/segment on a cxr: L heart margin?
Definition
lingula/inferior segment
Term
The following silhouette indicates which lobe/segment on a cxr: descending aorta?
Definition
LLL/superior and medial
Term
The following silhouette indicates which lobe/segment on a cxr: L diaphragm?
Definition
LLL/basal segments
Term
What type of pneumonia presents w/signs of bullous myringitis?
Definition
mycoplasma
Term
In what population and season does mycoplasma pneumonia occur?
Definition
young healthy adults, summer and fall mos
Term
How might lung sounds change as pneumonia progresses?
Definition
start w/early crackles, to rales (gurgly drowning quality) in some cases can cause wheeze and others
Term
What type of pneumonia might present w/similar sx to illnesses such as influenza or complications from influenza?
Definition
viral (differentiate based on h&p) (wbc- normal to slightly elevated. then you look at differential- neutrophils more than lymphocytes)
Term
Hemolytic anemia and rashes might indicate what type of pneumonia?
Definition
mycoplasma pneumonia
Term
Which of the following are useful for differentiating bacterial pneumonias: appearance, sx, hx?
Definition
come in a wide array of views and bacterial types. many appear similar. most have the same sx. hx is different!
Term
What aspect of exam is important when dx tb?
Definition
hx is important w/regard to any exposure, drug use, hiv+. also hx of fever, chills, weight loss (profound), night sweats are key! any positive ppd or prior use of inh or rifampin for tx
Term
Pt presents w/s/s of pneumonia and fevers, chills, weight loss of 10 lbs in the past 10 days, and night sweats. What type of pneumonia is likely?
Definition
tb
Term
What is a typical classical sign of tb? They won't tell you this- you have to ask.
Definition
night sweats are key!
Term
INH or Rifampin are used for tx of what illness?
Definition
TB
Term
What must you do w/pt admitted w/tb?
Definition
isolation
Term
What type of pneumonia has more apical infiltrates and *cavitary lesions*?
Definition
TB
Term
What type of pneumonia is found to be associated w/ hx of immunocompromised state, hx of geographic location (sw or ohio valley)? What are 3 examples?
Definition
fungal pneumonia- cryptococcus, coccidioides, histoplasma
Term
What percentage of fungal pnumonia clears w/o tx in young healthy adults? What is the mortality in the HIV population?
Definition
90%, 70% mortality-HIV
Term
What caused 182 cases of pneumonia and 29 deaths at a 1976 outbreak at the Philadelphia American Legion convention, and was found to be caused from the condensation of the air conditioners and also from contaminated water in institutions?
Definition
legionella pneumonia
Term
What is the tx of most cap in outpt setting?
Definition
most tx is empiric tx w/abx
Term
Outpt CAP tx w/abx involves coverage for what?
Definition
most common 2-3 pathogens: tx empirically- don't wait for test results
Term
Dose for CAP outpt abx depends on what?
Definition
age, renal function, co-morbid disease (cost)
Term
What sx should be tx w/pneumonia?
Definition
sx that are also the complaint of the pt (ask "what is the no. 1 thing that bothers you about the illness?")
Term
What should be rx for cough and sob w/pneumonia?
Definition
bronchodilators (albuterol)
Term
What should be rx for congestion in pneumonia pts?
Definition
nasal preparations
Term
What should be rx for cough/pain in pneumonia pts?
Definition
robitussin ac, tussionex
Term
What should be rx for *prevention* for elderly, renal and comorbid pts to prevent pneumonia?
Definition
pneumococcal vaccine
Term
What should be limited or eliminated with pneumonia pts?
Definition
limit or eliminate exposure to bcteria or infectious agents (tb, ac, contaminated h2o)
Term
What should be consulted when determining whether you admit a pneumonia pt?
Definition
Pneumonia Pt Outcomes Research Team (PORT): 19 clinical variables and determines if admission is necessary based on risk and mortality
Term
What could you rx for a pneumonia pt's cough?
Definition
anti-tussives (guifenasen, chlorpheramine, benzanoate (tessalon pearls))
Term
What are 3 other considerations beside PORT when deciding whether to admit a pneumonia pt?
Definition
compliance, social status, subjective look of pt
Term
What is the preferred and alternate abx tx for strep pneumoniae?
Definition
preferred: pcn g, amoxicillin. alt: macrolides, cephalosporins, doxycycline.
Term
board question: what ms should be taken w/post-splenectomy pt every year?
Definition
yearly pneumo vaccine
Term
What is the preferred and alternate abx tx for H. flu?
Definition
preferred: ceftriaxone, doxycycline, azithromycin, bactrim. alt: fluoroquinolone, clarithromycin
Term
What is the preferred and alternate abx tx for staph aureus?
Definition
preferred: pcn-resistant w or w/wo rifampin. for mrsa vancomycin w/ or w/o gentamycin, rifampin, linezolid. alt: cephalosporin, clindamcin, bactrim, fluroquinolone
Term
What is the preferred and alternate abx tx for klebsiella pneumonia?
Definition
3rd gen cephalosporin, add aminoglycoside for severe. alt: azitreonam umipenem, aminoglycoside, fluroquinolone.
Term
What is the preferred and alternate abx tx for e.coli?
Definition
3rd gen cephalosporin, add aminoglycoside for severe. alt: aztreonam, imipenem, aminoglycoside, fluroquinolone
Term
What is the preferred and alternate abx tx for pseudomonas aeroginosa?
Definition
anti-pseudomonal beta lactram aminoglycoside. alt: cipro + aminoglycoside or anti-pseudomonal beta lactam
Term
What is the preferred and alternate abx tx for
Definition
Term
If a pt's o2 stats are less than 90 or they are hypotensive, should you consider admittance?
Definition
admit. period.
Term
What is the preferred and alternate abx tx for anaerobes?
Definition
clindamycin, beta-lactam/beta lactamase inhibitor, imapenem. alt: none
Term
What is the preferred and alternate abx tx for mycoplasma pneumoniae?
Definition
preferred: doxycycline, erythromycin. alt: clarithromycin, azithromycin or a fluroquinolone.
Term
What is the preferred and alternate abx tx for legionella spp?
Definition
preferred: macrolide w/ or w/o rifampin, a fluroquinolone. alt: doxycycline w/ or w/o rifampin, bactrim
Term
How do you determine when to d/c pt w/pneumonia?
Definition
stable vital signs for 24-hr period. pt can take oral abx. pt can maintain adequate hydration and nutrition. pt's mental status is nml. pt has no other active clinical or psychosocial prob's requiring hospitalization. (also consider if they need home health or nursing stay if they live alone)
Term
What is the preferred and alternate abx tx for chlamydia?
Definition
preferred: doxycycline. alt: erythromycin, clarithromycin, azithromycin or a fluroquinolone.
Term
What is the preferred and alternate abx tx for moraxella catahraralis?
Definition
2nd or 3rd gen cephalosporin fluroquinolone. alt: bactrim, amoxicillin-clavulanic, macrolide.
Term
What is the preferred and alternate abx tx for p. jiroveci?
Definition
bactrim or pentamidine predinsone. alt: dapsone and trimetroprim. clindamycin and primaquine. trimetraxate adn folinic acid.
Term
Why might you prescribe alt tx?
Definition
allergy. pregnancy. child.
Term
What might you consider with a pneumonia complication of endobronchial obstruction?
Definition
you must consider an underlying cause (ie carcinoma, aspirated foreign body, cystic fibrosis)
Term
When dealing w/pneumonia complications of endobronchial obstruction, some pts may need what to determine root cause?
Definition
flexible bronchoscopy or a rigid bronchoscopy to determine root cause of obstruction. you can also obtain samples of tissue and fluid if needed.
Term
Kid w/big consolidated pneumonias, ask what?
Definition
how long has he had cough? weeks: maybe aspirated foreign body. then take family hx: sweat chloride test? (cf)
Term
What is empyema?
Definition
consolidated mass of infection (pus) loculated in the lung parenchuma.
Term
What is tx for empyema?
Definition
tx most of the time is thoracotomy and/or chest drain
Term
When can pericarditis occur? What causes this?
Definition
can occur after an infection w/pneumococcal spp. caused by the pneumonococcus bacteria.
Term
How prevalent is pericarditis?
Definition
although rare, these infections are severe and life threatening.
Term
How quickly does empyema develop? What should you do if you suspect empyema?
Definition
slowly. do another cxr do assess progression.
Term
What may pts require for dx/tx of pericarditis?
Definition
pericardiocentesis for fluid analysis and proper tx
Term
White to clear gelatinous infiltrate: gorilla sneezed into pericardium around heart. What does this describe?
Definition
pericarditis
Term
Global ST seg elevation is present in what complication of pneumonia?
Definition
pericarditis
Term
What is pleural effusion?
Definition
fluid build up in the lung space
Term
What complication of pneumonia decreases your v/q (ventilation to profusion) ratio?
Definition
pleural effusion
Term
What is key to know underlying cause of plueral effusion? Which pneumonias cause this?
Definition
hx and recent illness known are key. all pneumonia's can cause a pleural effusion.
Term
If pleural effusion is quite large or pt is symptomatic (moderate to severe breathing difficulty), what might pt require? What are you analyzing for?
Definition
thoracentesis or thoracotom/scope. fluid can be analyzed for infection, neoplasms, cells.
Term
What are 4 complications of pneumonia?
Definition
pleural effusion. endobronchial obstruction. empyema. pericarditis.
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