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PNB Quiz 3
RespII and Circ I
60
Biology
Undergraduate 4
06/29/2011

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Term
1) Partial Pressure
2) Solubility
3) Membrane Thickness
4) Surface area
5) Biconcave RBC shape for transport
Definition
Movement of gases across respiratory membrane affected by: (5)
Term
water vapor
Definition
Unlike atmospheric air, lung air is saturated with ______
Term
flow through
Definition
______ breathing is no mixing of incoming and outgoing air
Term
fish and birds
Definition
flow through breathing is seen in ______
Term
flow through breathing
Definition
Countercurrent exchange between water flowing across gills and blood (in gills) flowing in opposite direction
– Note O2 exchange not to equilibrium
Term
water breathers
Definition
Compared to mammals, ______ have much lower arterial + alveolar concentrations of CO2
Term
high solubility of CO2
Definition
water breathers have a much lower arterial + alveolar concentrations of CO2, due to _________ in water compared to air
Term
gain ; loss
Definition
Increasing ventilation in freshwater teleosts leads to water _____ and ionic (Na+) ______
Term
loss ; gain
Definition
Increasing ventilation in marine teleosts leads to a  water ____ and ionic _____
Term
surface area
Definition
More active species (which need more oxygen) rely on increased ________ to accommodate oxygen needs
Term
blood flow
Definition
Relatively inactive species (less oxygen need) increase ______ to the gills; and can tolerate the resulting change in ions
Term
high metabolisms
Definition
Air is much better medium for ventilation than water, but birds also have ______
Term
cross-current
Definition
unique to birds is the _______ gas exchange
Term
wings
Definition
skin breathing occurs in amphibians, aquatic reptiles, and in bats through their _____
Term
plasma ; hemoglobin
Definition
oxygen travels through the blood as it's dissolved in _____, and 98.5% of it is bound to ______
Term
polypeptide chains ; heme (Iron)
Definition
hemoglobin is composed of ________ and _______
Term
hemoglobin
Definition
seasons, aerobic activity, altitude, and stress/disease can all affect ______ levels in animals
Term
myoglobin
Definition
______ is composed of a monomer with one heme
Term
Type 1 (Red) skeletal ; cardiac
Definition
myoglobin stores oxygen in ______ and ______ muscle
Term
angiogenesis
Definition
knockout mice had far denser capillaries, when deals with the growth of new blood vessels from preexisting ones, known as _______
Term
pressure of oxygen (P02)
Definition
_____ is primary determinant of % Hb saturation
Term
loading
Definition
in the oxygen-hemoglobin dissociation curve, a shift to the left favors ______ of O2 onto hemoglobin
Term
release
Definition
in the oxygen-hemoglobin dissociation curve, a shift to the right favors ______ of O2 from hemoglobin
Term
greater
Definition
in a partially saturated hemoglobin molecule, the alveolar pressure is ______ than the blood pressure
Term
Bohr
Definition
the influence of acid/CO2 causing a shift right is known as the _____ effect
Term
root
Definition
the effect of acidosis on lowering blood oxygen content is known as the ______ effect
Term
swim bladder
Definition
bottom-dweller fish dont need this, and freshwater fish need this more than marine fish
Term
swim bladder
Definition
________ adjusts buoyancy by adjusting quantity of gas within
Term
lactic acid
Definition
In the swim bladder, the gas gland secretes _______, lowering pH of blood exiting
Term
carbonic anhydrase
Definition
Red blood cells use _______ enzyme to convert CO2 to HCO3+ in tissues; and back to CO2 in lungs
Term
fish
Definition
there are more HCO3- ions in (mammals/fish)
Term
medulla
Definition
the _____ is responsible for setting our respiratory rhythm
Term
DRG
Definition
The _______ receives input from chemoreceptors, lung receptors and baroreceptors
Term
DRG
Definition
The ______ sends out inspiratory neurons to VRG and PRC
Term
VRG
Definition
Former “expiratory
center”; contains rhythm+
generating Pre+Bötzinger
Complex and both I and E
neurons
Term
pacemakers
Definition
________ send excitatory output to other I neurons to produce inspiratory drive and inhibitory output to E neurons
Term
Pneumotaxic Center
Definition
In the PRC, the _______ “fine tunes” breathing rhythm and smooths out transitions from inspiration – expiration –inspiration…
Term
1) Rhythm
2) Activation
3) Ventilation
Definition
Brainstem Respiratory Control Centers Responsible For: (3)
Term
rate ; depth
Definition
Mammals increase ventilation by increasing ____and _____
of breathing
Term
CO2 and pH
Definition
_____ and ____ are by far the most important
regulatory chemicals
Term
decrease ; decrease ; increase
Definition
peripheral chemoreceptors are stimulated by a ______ in O2, ______ in pH, and _______ in CO2
Term
ventilation
Definition
the stimulation of chemoreceptors leads to increased _______
Term
pH
Definition
central chemoreceptors just sense _____
Term
erythrocytes (RBC)
Definition
small biconcave disks, Anuclear and lack organelles, mostly hemoglobin
Term
Erythropoeisis ; negative ; Erythropoietin
Definition
______ is the production of RBC, utilizing ______ feedback, and using the hormone __________
Term
platelet plug
Definition
Blood clotting starts with formation of a _______
Term
Thrombonin
Definition
cascade activates _______, which Catalyzes formation of loose Fibrin from inactive Fibrinogen
Term
Factor XIII
Definition
cascade activates _______, which is required to polymerize loose fibrin, in turn stabilizing it
Term
collagen
Definition
Damaged endothelium (lining blood vessel) exposes _______ to blood, which
is the primary stimulus for both platelet plug formation and coagulation
Term
closed
Definition
vertebrates have ______ circulatory systems
Term
ventricles
Definition
______ pump blood into arteries, away from the heart
Term
capillaries
Definition
exchange occurs across _______
Term
veins
Definition
______ return blood to the atria
Term
valves
Definition
______ ensure one way flow of blood in heart
Term
atria
Definition
the ______ receive blood
Term
greater
Definition
when pressure is _______ behind the valve, it opens
Term
striated

(and has a contraction mechanism)
Definition
like skeletal muscle, cardiac muscle is ______
Term
Bifurcations (forks);
anastomoses
– Intercalated Disks
• Desmosomes
• Gap Junctions
Action potential mechanism
– Excitation-contraction
Definition
unlike skeletal muscle, cardiac muscle has:
Term
ventricles
Definition
Proper sequence of excitation is crucial for proper sequence
of cardiac contraction (atria first THEN ________.
Term
contractile
Definition
Cardiac muscle action potential produced by _______ cells
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