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PN and EN
total parenteral nutrition and enteral nutrition and meds affected by it
57
Pharmacology
Graduate
08/09/2012

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Cards

Term
causes of under nutrition
Definition
starvation
impaired nutritional absorption
altered nutrition metabolism
Term
Marasmus
Definition
a form of protein-energy malnutrition mainly due to prolonged, severe caloric deficit.
look thin and malnourished
normal albumin/prealbumin
Term
kwashiorkor
Definition
a form of protein-energy malnutrition produced by sever protein deficiency.
belly sticks out
retarded growth, changes in skin and hair pigment, edema, immune deficiencies, pathologic changes in liver
Term
anorexia
Definition
loss of appetite, especially as a result of disease
Term
cachexia
Definition
weight loss, wasting o fmuscle, loss of appetite, weakness, loss of strength that can occur with chronic disease. (w/normal intake
Term
nutritional requirement depends on
Definition
age, gender, physical activity
current clinical status,
nutritonal status, organ fn/dysfn,
disease state
Term
visceral proteins
Definition
prealbumin, albumin, transferrin
Term
basal energy expenditure (BEE)
Definition
energy at rest
Term
total energy expenditure can be
Definition
estimated,calculated, or directly measure
Term
total enexpenditure
Definition
basal energy expenditure and energy used for physical activity combined
Term
estimation of energy expenditure in healthy adult, normal nutrition, min illness serverity
Definition
20-266 kcal/kg/day (using ABW)
Term
estimations of energy expenditure for illness, metabolic stress and BMI<30kg/m2
Definition
25-30 kcal/kg/day (uses ABW)
Term
estimation of energy expenditure for illness, metabolic stress and BMI> or equal to 30kg/m2
Definition
11-14 kcal/kg/day (use ABW)

22-25 kcal/kg/day (uses IBW)
Term
indirect calorimetry
Definition
measured way to get energy expenditure.
-usefull for critically ill or obese pts
-limitation is cost and not enough skilled personnel to use
-measure oxygen consumption and carbon dioxide production
Term
what alters the energy needs to pts
Definition
injury, infection, meds
Term
loop diuretics drug-nutrient interaction
Definition
hypOkalemia
hypOmagnesemia
Term
potassium sparing diuretics drug-nutrient interaction
Definition
hypERkalemia
Term
corticosteroid, cyclosporine drug-nutrient interaction
Definition
hypERglycemia
Term
propofol drug-nutrient interaction
Definition
hypERtriglyceridemia
Term
antibiotics drug-nutrient interaction
Definition
vitamin K deficiency
Term
cholestyramine drug-nutriend interaction
Definition
fat soluble vitamin deficiency
Term
oral nutrition
Definition
whole food by mouth
Term
enteral nutrition
Definition
nasogastric tube
nasoduodenal tube
nasojejunal tube
gastromy tube-into stomach
jejunostomy tube-into intestines
Term
enteral nutrition support
Definition
if gut works, use it
-length of stay decr
-return of cognitive fcn
-maintain gut integrity
Term
if risk of malnourishment, unsafe to swallow/poor oral intake, and non-functional GI tract then use
Definition
parenteral nutritional support
Term
parenteral nutrition
Definition
complete bypass of GI Tract
Term
general indications for PN
Definition
1- inability to absorb nutrients via enteral route
2- EN ia contraindicated or unlikely to provide adequate nutrition w/in 5-7 days
3- mod-severe malnourished cancer pts
4- pts w/eating disorder
Term
peripheral parenteral nutrition
Definition
peripheral vein
- mild-mod stressed pts w/o central access
-lower concen of macro/micro nutrients to prevent necrosis and phlebitis of vein
-lower risk of infection than tpn
Term
central PN
Definition
-large central vein
- pts req greater than 7-14 days in hosp or indefintely @home
- higly concen hypertonic solns
-higher risk of complications/infections than PPN or EN
Term
TPN lines
Definition
Tunnele central venous catheter
PICC: peripherally inserted central line
non-tunneled CVC
Term
PPN lines
Definition
femoral vein
midline peripheral catheter
peripheral catheter
Term
PN administration methods
Definition
continous and cyclic
Term
components of PN
Definition
AA, CHO, IVFE, sterile water
elctrolytes, minerals, vits, trace elements, other (meds)
Term
types of PN solutions
Definition
1- 2-in-1= CHO+AA w/ IVFE piggyback
2- 3-in-1=CHO+AA and IVFE in one bag
Term
1 mL IVFE equal
Definition
1.1 kcal 10% emulsion
2kcal 20% emulsion
3 kcal 30%emulsion
Term
30% IVFE not intended for
Definition
direct IV administration
Term
Egg allergy
Definition
fat emulsions made with egg phospholipids
Term
propofol (iv anesthetic) formulated in 10% intralipid so
Definition
need to adjust pt nutritional requirment due to high source of calories
Term
multivitamins should be in
Definition
all adult PN fomrulations
13 essential vitamins
Term
trace elements essential in PN
Definition
zinc
copper
chromium
manganese
Term
high doses of supplemental zinc and chromium needed for
Definition
pts w/ high output ostomies and diarrhea
Term
molybdenum and selenium not in PN for
Definition
pts with renal failure
Term
manganese and copper not in PN for
Definition
pts with cholestatic liver disease
Term
essentiel electrolytes
Definition
sodium, potassium
magnesium, calcium
phosphorus, acetate
Term
examples of meds compatible with PN soln
Definition
insulin
famotidine
ranitadine
Term
fats % of total calories
Definition
20-35%
Term
to minimize unstable tpn
Definition
aa >4%
cho >10%
ivfe >2%
Term
mechanical tpn complications
Definition
infusion pump/tubing fail
catheter related complications
Term
infectious complications of tpns
Definition
bacterial infections
fungal infections
Term
metabolic tpn complications
Definition
hyperglycemia
liver disease
refeeding syndrome
Term
refeeding syndrome
Definition
can be fatal
phosphate levels decrease
-to avoid start at low tpn rate
Term
EN protein needed daily
Definition
0.8-3 g/kg of protein EN
burns at high end 3g/kg/day
infection, trauma 2 g/kg/day
older 60 yrs 1g/kg/day
Term
metabolic complication for EN
Definition
hyperglycemia
refeeding syndrome
fluid electroyte imbalance
Term
mechanical complications EN
Definition
tube clog
tube displacement/inadvertent removal by pt
risk of entering tracheobronchial tree
Term
gastrointestinal en cmplications
Definition
n/v
ab distention, cramping
aspiration-pneumonia
diarrhea
constipation
Term
hypermetabolic pts protein needed for EN daily
Definition
3g/kg/day
25 kcal/kg/day-total calories
Term
renal disease or hepatic encephalopathy protein needs for en
Definition
lower protein start at 0.8 g/kg/day
no more than 1.5g/kg/day
except when start dialysis
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