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Title: Placental pathology

Description: 5.1.07

Total Flash Cards: 14

Created: 05/01/2007 16:46:10

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Cards

Term
what is placenta previa?
Definition
placenta implants very low in the uterus, covering the internal os. The cervial dialation (at the time of labor) will cause severe bleeding and fetal/maternal death
Term
decidua?
Definition
endomentrium modified by progesterone (and able to be shed) and separates the placenta from the myometrium
Term
placenta accreta
Definition
endometrium is defective, (like at the site of a previous C-section)--placenta grows into muscle.
Term
ascending infection
Definition
most common route. results in amniotic fluid infection and cause chorioamnionitis as an inflammatory response. frequent cause of premature oset of labor. caused by bacteria and less commonly candida
Term
hematogenous
Definition
rare, results in villitis. caused by viruses, toxoplasmosis, symphylis,
Term
placental abruptio
Definition
rupture of retroplacental (decidual) blood vessel. related to materal hypertensino, may cause large retroperitoneal hemorrhage with spearation of placenta from blood supply and fetal death
Term
narrowing or thrombosis of retroplacental (decidual) blood vessels
Definition
causes ischemia and placental infarts. numberous placental infarts will comprimise the delivery of O2 and nutrients to the fetus, resulting in either fetal growth restriction or fetal death
Term
MZ
Definition
division of 1 fertilized ovum, and either monochrorionic or dichorionic
Term
DZ
Definition
fertilization of 2 ova, and dichorionic
Term
multiple preg complications
Definition
Preterm labor Malformations Twin-twin transfusion
Term
hydatidiform mole
Definition
Trophoblastic proliferation; Cystic swelling of chorionic villi; May precede choriocarcinoma
Term
parial mole
Definition
vv
Term
why do moles happen?
Definition
paternal DNA is more heavily methylated which is linked to abnormally prominent development of extraembryonal tissues (such as trophoblasts)
Term
what are the gross findings of moles?
Definition
graple-like swollen villi covered with proliferating trophoblast. and HCG levels are abnormally evelvated



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