Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| how can staph adhere to traumatized endo |
|
Definition
| fibrinogen, fibronectin, thrombospondin, laminin, c iv |
|
|
Term
|
Definition
|
|
Term
| what does staph prot a do? |
|
Definition
| binds Fc, complement, antiphagocytic |
|
|
Term
|
Definition
| coag, lip, hyal, staphylokinase, nuc, catalase, clumping factor |
|
|
Term
|
Definition
| a, b, g, d, leuk (greeks) |
|
|
Term
|
Definition
| a, b, c1, c2, d, e, enterotoxin f |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| teichoic acid of coag neg staph |
|
Definition
|
|
Term
|
Definition
| naf, oxa, dicloxa / e,v + clinda / MRSA vanco, bactrim + rif/gent |
|
|
Term
| what abx is not for MRSA? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| what causes scarlet fever? |
|
Definition
| sequella of strep pharyngitis, caused by exotoxin |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| cardiac histo in rh fever? |
|
Definition
|
|
Term
| what is deposited in glomeruli in acute post-strep glomerulonephritis? |
|
Definition
|
|
Term
|
Definition
| PS, lipoteichoic, lysins, streptokinase, hyaluronidase, nuclease, c5a peptidase, M, SPE |
|
|
Term
| s. pyo: fxn of protein F? |
|
Definition
| bind fibronectin in epithelials |
|
|
Term
| s. pyo: fxn of M protein? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| group of strep agalactiae |
|
Definition
|
|
Term
|
Definition
| neonatal pneumo, wound, endocard |
|
|
Term
|
Definition
| cn + genta, emycin, clinda |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| what does entero do to bile |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| uti, wound, sep, endocarditis |
|
|
Term
| virulence factors of entero |
|
Definition
| agg, adhesins, cytolysin, pheromone, gelatinase |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| intrisic, intermediate resist |
|
|
Term
| what drugs don't work on entero? |
|
Definition
| ceph, bact, aminoglycosides |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| major VF for s. pneumoniae ? |
|
Definition
| capsule prevents C3b fxn in alt path |
|
|
Term
| what other capsules does s. pneumoniae cross react with |
|
Definition
|
|
Term
| s. pneumoniae: what does pneumolysin do? |
|
Definition
| damages ciliated cells, activates classical complement |
|
|
Term
| s. pneumoniae: what does phosphorylcholine do? |
|
Definition
|
|
Term
| s. pneumoniae: what does TA/PG do? |
|
Definition
| activates complement by alt path |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| what does optochin do to s. pneumo ? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| RF for s. pneumo pneumonia? |
|
Definition
| EtOH, DM, lung/renal dz, malig |
|
|
Term
| alveolar fluid thingy for s. pneumo |
|
Definition
|
|
Term
| 3 biggies for s. pneumo dx |
|
Definition
| optochin sens, a hemo, liquefied by bile |
|
|
Term
|
Definition
| PCN (some resist), ceph, emycin (other macs), fluoroquinolones(floxacin) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| cultural char of neisseria |
|
Definition
| Co2, chocolate agar, OXIDASE+ |
|
|
Term
| antigens of n. meningitidis |
|
Definition
|
|
Term
|
Definition
|
|
Term
| how does n. meningitidis get to the submucosa? |
|
Definition
| transverses cell in vesicle |
|
|
Term
|
Definition
| shock, hemm, purpura, destruction of adrenals |
|
|
Term
| abx for n. meningitidis ? |
|
Definition
| pcn, ceph, chloramphenicol |
|
|
Term
| prophylaxis for n. meningitidis ? |
|
Definition
|
|
Term
| antigens of n. gonnorhoaea ? |
|
Definition
|
|
Term
| n. gonnorhoaea : what does OMP I do? |
|
Definition
| pores, prevents PMN degran, fac invasion, resists complement |
|
|
Term
|
Definition
|
|
Term
| discuss genetic var of pili in n. gonnorhoaea |
|
Definition
| pilS to pilE, recomb with xformed DNA from other species |
|
|
Term
| discuss gen var of Opa in n. gonnorhoaea |
|
Definition
| 11 genes, switch on/off by frameshifting by varrying 5nt repeats |
|
|
Term
| discuss gen var of LOS in n. gonnorhoaea |
|
Definition
| can be sialated --> resist complement |
|
|
Term
| cultural char of n. gonnorhoaea |
|
Definition
| chocolate agar (fastidious) and enhanced co2 |
|
|
Term
| two ligands for n. gonnorhoaea attachment |
|
Definition
|
|
Term
| where do n. gonnorhoaea pili attach |
|
Definition
| ure, vag, fallo, sperm, neutros |
|
|
Term
| where do n. gonnorhoaea opa attach |
|
Definition
|
|
Term
| what does OMPI do in n. gonnorhoaea |
|
Definition
|
|
Term
| how does n. gonnorhoaea get to the prostate, epididymus, paracervical glands? |
|
Definition
|
|
Term
| how does n. gonnorhoaea get to fallopian tubes? |
|
Definition
|
|
Term
| 6 ways n. gonnorhoaea resist immunity |
|
Definition
| ant var, opa/pilli resist phag, neutrophil lactoferring binding, iga1 protease, LOS sialation, bind Ab to rmp |
|
|
Term
| sense of GS for n. gonnorhoaea |
|
Definition
|
|
Term
| special medium for n. gonnorhoaea |
|
Definition
|
|
Term
|
Definition
| ceftriaxone, cefixime, cipro, oflox, levoflox, gatiflox + azith or doxy |
|
|
Term
| 2 types of PCN resistance in n. gonnorhoaea |
|
Definition
| dec affinity for PBP, plamid conferring b-lactamase (PPNG) |
|
|
Term
|
Definition
|
|
Term
| what causes brazilian purpuritic fever? |
|
Definition
|
|
Term
|
Definition
| PS, pili, HMW1, HMW2, endotoxin |
|
|
Term
| major virulence factor for h.flu? |
|
Definition
|
|
Term
| culture requirements for h.flu? |
|
Definition
|
|
Term
| why can h.flu grow around sa? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| what are the major clinc char of h.flu b under 2 years of age? |
|
Definition
| meningitis, septicemia, cellulits |
|
|
Term
| what are the major clinc char of h.flu b 2-5 years of age? |
|
Definition
|
|
Term
| how do you prophylax h.flu households? |
|
Definition
|
|
Term
| what dz do unencapsulated h.flu cause? |
|
Definition
| sinusitis, OM, exacerbate bronchitis |
|
|
Term
| how does h.flu get across cells? |
|
Definition
|
|
Term
| conjunctivitis --> fever, p/p, shock |
|
Definition
|
|
Term
| what does type "b" h.flu refer to? |
|
Definition
|
|
Term
|
Definition
| amp, ceph, tet, macro, fluoro, bactrim |
|
|
Term
| resistance profile of h.flu? |
|
Definition
| 25-50% are ampR due to b-lactamase |
|
|
Term
| other haemophilus of conjunctivits? |
|
Definition
|
|
Term
| other haemophilus of endocard? |
|
Definition
|
|
Term
| other haemophilus of chancroid? |
|
Definition
|
|
Term
| which haemophilus grows in co2? |
|
Definition
| aphrophilus (think endocarditis) |
|
|
Term
|
Definition
|
|
Term
| what does B. parapertussis cause? |
|
Definition
|
|
Term
| adhesins of B. pertussis? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| binds to integrins on resp cells, bind CR3 along with pertactin |
|
|
Term
|
Definition
| macrophage receptor that promotes phag w/o resp burst |
|
|
Term
| what does Pertussis toxin A do? |
|
Definition
| ribosylates a ADP-Gprot to prevent inact, inc secretions and mucous, promote lymphocytosis |
|
|
Term
| what does Pertussis toxin B do? |
|
Definition
| binds resp cells and phags |
|
|
Term
| where is adenylate cyclase toxin? |
|
Definition
|
|
Term
| what does adenylate cylcase toxin do? |
|
Definition
| inc cAMP, dec chemotaxis and superoxide production B. pertussis |
|
|
Term
| where is tracheal cytotoxin? |
|
Definition
|
|
Term
| what does trachael cytotoxin do? |
|
Definition
| piece of pg causes extrusion of ciliated resp cells in B. pertussis |
|
|
Term
| where is dermonecrotic toxin? |
|
Definition
|
|
Term
| culture for B. pertussis? |
|
Definition
|
|
Term
|
Definition
| regulates Pt, ACT, Fha, pili, dermonecrotic tox |
|
|
Term
|
Definition
| S=sensor, A=DNA binder (B. pertussis) |
|
|
Term
| what characterizes the catarrhal stage of B. pertussis infection? |
|
Definition
| rhinorhea, fever, sneezing, anorexia |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| special stain for legionella? |
|
Definition
|
|
Term
| how do legionella get energy? |
|
Definition
|
|
Term
| catalase state of legionella? |
|
Definition
|
|
Term
| where do legionella replicate? |
|
Definition
|
|
Term
| how does legionella get into phags? |
|
Definition
|
|
Term
| how does legionella kill cells? |
|
Definition
|
|
Term
| what is required for legionella immunity? |
|
Definition
|
|
Term
| special media for legionella? |
|
Definition
|
|
Term
|
Definition
| macrolides, fluoroquinolones (floxacins) |
|
|
