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Physiology - Test II - Intro to Pulmonary Phys
All questions from Intro
15
Physiology
Graduate
03/15/2011

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Cards

Term
What happens to the shape of the diaphragm as it contracts?
Definition
It shortens and flattens, increasing the volume of the thorax.
Term
What substantial structure separates the two lungs?
Definition
The mediastinum
Term
How many "generations" or levels exist in the lungs?

In which levels does gas exchange take place?
Definition
23

The last four generations of airways; 20-23
Term
What is the approximate number of alveoli in the lungs?
Definition
8,000,000
Term
What is the approximate geometry of individual alveoli?
Definition
hexagonal
Term
What is the pproximate diameter of alveoli?
Definition
100mm
Term
Describe alveolar walls.
Definition
Essentially flat, basically a meshwork of capillaries.
Term
What are anastomoses?

What is their function?
Definition
Connections between bronchial and pulmonary capillaries

Usually little function in healthy adults; may open in pathological conditions, such as when blood flow is blocked to a portion of the lung
Term
What is the diffusion distance for gases to move from the alveolar space to erythrocytes?
Definition
0.2 - 0.5 microns
Term
Describe diffusion time for gases.
Definition
Very short, almost instantaneous
Term
What is the pathway from alveolus to erythrocyte in gas exchange?
Definition
Alveolar epithelium -> interstitial space -> endothelial cells -> plasma -> erythrocyte
Term
What is the pressure of the atmosphere at sea level?
Definition
760 mmHg
Term
What percentage of barometric pressure is exerted by O2 vs. N2 molecules?

What are their partial pressures?
Definition
21% O2
79% N2

PO2 = 0.21 * 760 = 160mmHg
PN2 = 0.79 * 760 = 600mmHg
Term
What is the conversion between mmHg and cm H20?
Definition
1 mmHg = 1.34 cm H20
Term
What is the partial pressure of water vapor at body temperature?
Definition
47 mmHg
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