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Physiology Exam 4- Lecture 10
Motor Control: Brainstem and Cerebral Cortex
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Physiology
Professional
11/13/2011

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Term
What are the two major functional groups of the brainstem descending pathways?
Definition
1. Medial systems (posture)

2. Lateral systems (fine dextrous movements)
Term
What are the two tracts in the medial system (the brainstem descending pathway)?
Definition
1. Vestibulospinal tract
2. Reticulospinal tract
Term
Describe the vestibulospinal tract (the brainstem descending pathway)
Definition
Originate in vestibular nuclei and project to spinal cord

-Uncrossed (ipsilateral)

-Mainly excites extensors and inhibits
flexors
Term
Describe the reticulospinal tract (the brainstem descending pathway)
Definition
-Originate in medullary and pontine reticular formation and project to spinal cord

-Mainly uncrossed

-Pontine reticulospinal tract mainly excites extensors and inhibits flexors, and medullary reticulospinal tract mainly excites flexors and inhibits extensors
Term
What are the two tracts in the lateral system (the brainstem descending pathway)?
Definition
1. Corticospinal tract
2. Rubrospinal tract
Term
Describe the corticospinal tract (the brainstem descending pathway)
Definition
-Originates in cerebral cortex
and projects to spinal cord

-Crossed (85%)

-Mainly excites flexors in distal limbs and digits, and inhibits extensors.
Term
Describe the rubrospinal tract (the brainstem descending pathway)
Definition
-Originates from red nucleus in midbrain and projects to spinal cord

-Crossed

-Mainly excites flexors in proximal limbs and hands, and inhibits extensors
Term
Define "motor cortex"
Definition
Any area that, when stimulated, produces some sort of movement
Term
What is the difference between the primary motor cortex and the premotor cortex?
Definition
The primary motor cortex produces focal movements under low intensity

Premotor cortex requires high intensity and moves groups of muscles
Term
Describe the frontal eye fields. Are they in the motor cortex?
Definition
Although considered to be motor cortex, do not connect with the primary motor cortex; instead, they project to regions controlling saccadic eye movements
Term
How is the primary cortex organized?
Definition
Stomatopically, with the leg on the medial surface and the face more inferior

Larger areas for fingers and mouth, for finer movements
Term
Is the primary motor cortex contralateral?
Definition
Yes, but it normally influences unilateral movements. The contralateral input is more of a "backup" control for distal limbs in the event of lesion.
Term
Define fractionated movements
Definition
The finely controlled, dexterous movements across a single joint, which permit the detailed coordinated movements of our fingers and hands.

Executed by the primary motor cortex
Term
What is the role of the supplementary motor cortex (aka medial premotor cortex)?
Definition
To coordinate bilateral movements on both sides of the body, adjust posture needed for a movement, and to mentally rehearse movements
Term
What is the role of the lateral premotor cortex?
Definition
Coordinating unilateral movements, performing correct movements related to the environment (ex. catching a ball), adjust posture as needed
Term
How are the supplementary motor cortex and lateral premotor cortex organized?
Definition
Stomatopically, but less so than the primary motor cortex
Term
What is the role of the cingulate motor cortex?
Definition
Not understood, but may have functions similar to the supplementary motor cortex or can be involved in showing emotion with the limbic system
Term
What is the role of the frontal eye field
Definition
To control voluntary conjugate saccadic eye movements (the fast eye movements)
Term
Describe stimulation/lesion results in the frontal eye field
Definition
Stimulation of the frontal eye field on one side causes saccadic eye movements toward the opposite side; a lesion produces eye deviation toward the side of the lesion.
Term
What two regions of the cortex do not ultimately project to alpha motor neurons, but do influence movements?
Definition
Somatosensory cortex, posterior parietal lobe
Term
What is the role of the somatosensory cortex in movement?
Definition
Receives somatosensory input and relays this information to the complementary motor region

Descending output influences sensory input; can modulate sensory input to a level appropriate for an occasion.
Term
What is the role of the posterior parietal lobe in movement?
Definition
Coordinates visual (spatial) information with movement (the dorsal "where" pathway)
Term
In the corticospinal tract, from where do the fibers originate?
Definition
30% primary motor cortex
30% premotor areas
40% somatosensory cortex
Term
Define lower motor neuron
Definition
Spinal motoneurons or nerves, or cranial nerve motor neurons
Term
Define upper motor neuron
Definition
Refers to corticospinal neurons or other descending neurons above
spinal cord
Term
What are signs of damage to lower motor neurons?
Definition
1. Decreased muscle tone
2. Muscle atrophy
3. Muscle fasciculations or fibrillations of single fibers
4. Absence of tendon reflexes
5. No Babinski sign
Term
What are signs of damage to upper motor neurons?
Definition
1. Decreased muscle tone (hypotonia) initially, becoming increased muscle tone (hypertonia, spasticity) with time
2. Rarely have muscle atrophy
3. Affects groups of muscles instead of a single muscle
4. Enhanced stretch reflexes (hyperreflexia)
5. Babinski sign present
Term
What is the Babinski sign?
Definition
Extensor plantar response

Normal response: stroke lateral aspect of foot with sharp object causes flexion of toes

Damage to pyramids (corticospinal tract): Big toe invariably extends, and other toes frequently fan out.
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